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Ayse Nurcan Cebeci Paediatric Endocrinology, Department of Friedrich-Alexander University Hospital, Erlangen, Germany

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Vera Schempp Paediatric Endocrinology, University Hospital, Bonn, Germany

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Katharina Förtsch Paediatric Endocrinology, University Hospital, Düsseldorf, Germany

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Bettina Gohlke Paediatric Endocrinology, University Hospital, Bonn, Germany

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Michaela Marx Paediatric Endocrinology, Department of Friedrich-Alexander University Hospital, Erlangen, Germany

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Helmuth-Guenther Dörr Paediatric Endocrinology, Department of Friedrich-Alexander University Hospital, Erlangen, Germany

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Joachim Woelfle Paediatric Endocrinology, Department of Friedrich-Alexander University Hospital, Erlangen, Germany

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, antithyroid drug; BR, block and replace; C, carbimazole; D, dose titration; f, female; m, male; LT4, levothyroxine; M, methimazole. The clinical characteristics of children with GD and DS in comparison with GD children without DS are shown in Tables

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-24-0032
Volume/Issue:
Volume 13: Issue 6
Open access
Irfan Vardarli Department of Medicine I, Klinikum Vest, Knappschaftskrankenhaus Recklinghausen, Academic Teaching Hospital, Ruhr-University Bochum, Recklinghausen, Germany

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Manuel Weber Department of Nuclear Medicine, University Hospital Essen, Essen, Germany

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Frank Weidemann Department of Medicine I, Klinikum Vest, Knappschaftskrankenhaus Recklinghausen, Academic Teaching Hospital, Ruhr-University Bochum, Recklinghausen, Germany

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Dagmar Führer Department of Endocrinology, Diabetes and Metabolism, Clinical Chemistry – Division of Laboratory Research; Endocrine Tumor Center at WTZ/Comprehensive Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

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Ken Herrmann Department of Nuclear Medicine, University Hospital Essen, Essen, Germany

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Rainer Görges Department of Nuclear Medicine, University Hospital Essen, Essen, Germany

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complications and the necessity for life-long levothyroxine supplementation. In iodine-deficient countries, bilateral goiter is common, require total thyroidectomy regardless of the level of serum calcitonin. In the latter scenario, the level of calcitonin may

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0030
Volume/Issue:
Volume 10: Issue 3
Open access
Agnieszka Adamska Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland

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Paulina Tomczuk-Bobik Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland

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Anna Beata Popławska-Kita Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland

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Katarzyna Siewko Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland

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Angelika Buczyńska Clinical Research Centre, Medical University of Bialystok, Białystok, Poland

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Piotr Szumowski Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland

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Łukasz Żukowski Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland

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Janusz Myśliwiec Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland

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Monika Zbucka-Krętowska Department of Gynecological Endocrinology and Adolescent Gynecology, Medical University of Bialystok, Białystok, Poland

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Marcin Adamski Faculty of Computer Science, Bialystok University of Technology, Białystok, Poland

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Adam Jacek Krętowski Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
Clinical Research Centre, Medical University of Bialystok, Białystok, Poland

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study. All women were treated with a single dose of RAI (100 mCi) for advanced PTC within 3 months after operation (from 30 to 90 days). All women were treated with levothyroxine immediately after surgery (dose 100–150 µg/day). Treatment with RAI was

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0187
Volume/Issue:
Volume 10: Issue 10
Open access
Giorgio Grani Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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Livia Lamartina Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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Vito Cantisani UOS Innovazioni Diagnostiche e Ultrasonografiche, Azienda Ospedaliera Universitaria Policlinico Umberto I, ‘Sapienza’ University of Rome, Rome, Italy

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Marianna Maranghi Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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Piernatale Lucia Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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Cosimo Durante Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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of a benign cytology report or the absence of suspicious sonographic features. Exclusion criteria were levothyroxine therapy during the study or in the 6 months preceding enrollment, history of surgical or nonsurgical thyroid interventions, history of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0336
Volume/Issue:
Volume 7: Issue 1
Open access
Laura van Iersel Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands

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Sarah C Clement Department of Pediatrics, Amsterdam University Medical Center, location VU University Medical Center, Amsterdam, The Netherlands

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Antoinette Y N Schouten-van Meeteren Department of Pediatric Oncology, Emma Children’s Hospital, Amsterdam University Medical Center, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands

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Annemieke M Boot Department of Pediatric Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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Hedi L Claahsen-van der Grinten Department of Pediatric Endocrinology, Amalia Children’s Hospital, Radboud University Medical Center, Nijmegen, The Netherlands

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Bernd Granzen Department of Pediatrics, Maastricht University Medical Center, Maastricht, The Netherlands

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K Sen Han Department of Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands

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Geert O Janssens Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands

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Erna M Michiels Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands

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A S Paul van Trotsenburg Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Center, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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W Peter Vandertop Neurosurgical Center Amsterdam, Amsterdam University Medical Center, location Academic Medical Center, University of Amsterdam and location VU University Medical Center, Amsterdam, The Netherlands

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Dannis G van Vuurden Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Pediatric Oncology/Hematology, Amsterdam University Medical Center, location VU University Medical Center, Amsterdam, The Netherlands

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Hubert N Caron Department of Pediatric Oncology, Emma Children’s Hospital, Amsterdam University Medical Center, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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Leontien C M Kremer Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Pediatrics, Emma Children’s Hospital, Amsterdam University Medical Center, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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Hanneke M van Santen Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands

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they are maintained within the reference range ( 6 ). For this reason, adults with ≥ 20% reductions in FT4 concentrations may be presumed to have mild central hypothyroidism and may be replaced with levothyroxine therapy (LT4), although high

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0311
Volume/Issue:
Volume 7: Issue 12
Open access
Maria Giannakou Endocrine Unit, Department Med Therapeutics, Alexandra Hospital, School of Medicine, National Kapodistrian University, Athens, Greece

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Katerina Saltiki Endocrine Unit, Department Med Therapeutics, Alexandra Hospital, School of Medicine, National Kapodistrian University, Athens, Greece
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece

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Emily Mantzou Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece

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Eleni Loukari Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece

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Georgios Philippou Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece

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Konstantinos Terzidis Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece

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Charalampos Stavrianos Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece

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Miltiades Kyprianou Endocrine Unit, Department Med Therapeutics, Alexandra Hospital, School of Medicine, National Kapodistrian University, Athens, Greece

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Theodora Psaltopoulou Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National Kapodistrian University, Athens, Greece

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Kalliopi Karatzi Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, Greece

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Maria Alevizaki Endocrine Unit, Department Med Therapeutics, Alexandra Hospital, School of Medicine, National Kapodistrian University, Athens, Greece
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece

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Altay M Yilmaz FM Topcuoglu C Yilmaz N Berker D Guler S. The impact of levothyroxine sodium treatment on oxidative stress in Hashimoto’s thyroiditis . European Journal of Endocrinology 2016 174 727 – 734 . ( https://doi.org/10.1530/EJE-15

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0272
Volume/Issue:
Volume 7: Issue 9
Open access
Xiujuan Su Department of Women & Children’s Health Care, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China

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Yan Zhao Department of Women & Children’s Health Care, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China

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Zhijuan Cao Department of Women & Children’s Health Care, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China

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Yingying Yang Department of Women & Children’s Health Care, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China

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Tony Duan Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China

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Jing Hua Department of Women & Children’s Health Care, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China

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universal World Health Organization (WHO) recommended range. Second, none of the women with isolated hypothyroxinaemia was prescribed levothyroxine in our institution, so bias regarding the treatment for hypothyroxinaemia could be excluded. Third, the large

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0088
Volume/Issue:
Volume 8: Issue 4
Open access
Yongping Liu Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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Shuo Wang Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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Qingling Guo Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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Yongze Li Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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Jing Qin Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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Na Zhao Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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Yushu Li Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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Zhongyan Shan Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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Weiping Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, China Medical University, Shenyang, People’s Republic of China

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them had taken levothyroxine. All participants provided written informed consent prior to enrolment. The study was approved by the Ethics Institutional Review Board of China Medical University prior to initiating subject recruitment. After 8 h of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0132
Volume/Issue:
Volume 6: Issue 8
Open access
Xingyao Tang Beijing Tongren Hospital, Capital Medical University

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Zhi-Hui Song Department of Pharmacy, Beijing Tongren Hospital, Capital Medical University, Beijing, China

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Dawei Wang General Practice Department, Beijing Tongren Hospital, Capital Medical University, Beijing, China

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Jinkui Yang Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China

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Marly Augusto Cardoso Department of Nutrition, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil

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Jian-Bo Zhou Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China

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Rafael Simó Endocrinology and Nutrition Department, Hospital Universitari Vall d’Hebron, Diabetes and Metabolism Research Unit, Vall d’Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain

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Failure 2018 11 e005266. ( https://doi.org/10.1161/CIRCHEARTFAILURE.118.005266 ) 39 Wändell P Carlsson AC Li X Sundquist J Sundquist K Levothyroxine treatment and incident dementia in adults with atrial fibrillation . Aging Clinical and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0047
Volume/Issue:
Volume 10: Issue 4
Open access
Thera P Links Division of Endocrinology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

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Trynke van der Boom Division of Endocrinology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

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Wouter T Zandee Division of Endocrinology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

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Joop D Lefrandt Division of Vascular Medicine, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands

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G Cardiac effects of long term thyrotropin-suppressive therapy with levothyroxine . Journal of Clinical Endocrinology and Metabolism 1993 77 334 – 338 . ( https://doi.org/10.1210/jcem.77.2.8345037 ) 22 Smit JW Eustatia-Rutten CF Corssmit

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0539
Volume/Issue:
Volume 10: Issue 1
Open access