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skin metabolism but also through associated complications such as vasculopathies, neuropathies or immunological impairment and ensuing skin infections. Especially the hyperglycaemia-induced, non-enzymatic glycation of cell structures plays a decisive
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at least 80 nmol/L to normalise their insulin resistance ( 37 ). Also, in prediabetes with early hyperglycaemia, it took achieved 25(OH)D values of 100 nmol/L in the D2d trial for insulin resistance to be reduced ( 38 ), though 25(OH)D values of 25
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hyperglycaemia: report of a WHO/IDF Consultation , 2006 . 19 Eades CE France EF Evans JMM . Prevalence of impaired glucose regulation in Europe: a meta-analysis . European Journal of Public Health 2016 26 699 – 706 . ( https://doi.org/10.1093/eurpub
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Introduction Adult growth hormone deficiency (AGHD) is associated with increased visceral adiposity, insulin resistance, dyslipidaemia and hyperglycaemia ( 1 ). AGHD may persist from childhood or be acquired in adulthood as a result of
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Care 2010 33 676 – 682 . ( https://doi.org/10.2337/dc09-1848 ) 22 WHO . Diagnostic Criteria and Classification of Hyperglycaemia First Detected in Pregnancy . Geneva : World Health Organization , 2013 . 23 Ellingsgaard H Hauselmann I Schuler
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Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland
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-00194 ). 160 Luo P Dematteo A Wang Z Zhu L Wang A Kim HS Pozzi A Stafford JM Luther JM Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice . Diabetologia 2013 56 901 – 910 . ( https
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cholesterol, QRisk3 score, and liver stiffness measurements ( 65 ). Optimisation of cardiometabolic risk Cardiometabolic interventions in NAFLD are founded on the central hypothesis that reversal of insulin resistance and hyperglycaemia alleviates
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ovary syndrome phenotype . Journal of Obstetrics and Gynaecology Research 2016 42 837 – 843 . ( https://doi.org/10.1111/jog.12985 ) 10.1111/jog.12985 17 Laakso M Kuusisto J. Insulin resistance and hyperglycaemia in cardiovascular disease
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Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
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Department of Renal Medicine, St George Hospital, Sydney, NSW, Australia
Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia
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diabetes, where inadequate insulin treatment fails to suppress both ketogenesis and blood glucose levels (leading to hyperglycaemia and profound dehydration). Euglycemic ketoacidosis has been a very rare occurrence in RCTs. For example, in the DAPA