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Anna Olsson-Brown Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
The Clatterbridge Cancer Centre, Wirral, UK

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Rosemary Lord The Clatterbridge Cancer Centre, Wirral, UK

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Joseph Sacco The Clatterbridge Cancer Centre, Wirral, UK
Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK

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Jonathan Wagg Roche Innovation Center, Basel, Switzerland

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Mark Coles Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK

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Munir Pirmohamed Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK

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identified, and baseline TSH does not appear to predict the occurrence of thyroiditis ( 12 ). ICI treatment duration may be positively correlated with the occurrence of thyroiditis ( 15 ). The aim of our paper was to characterise the longitudinal clinical

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0473
Volume/Issue:
Volume 9: Issue 4
Open access
Danuta Gąsior-Perczak Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland

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Iwona Pałyga Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland

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Monika Szymonek Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland

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Artur Kowalik Department of Molecular Diagnostics, Holycross Cancer Centre, Kielce, Poland

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Agnieszka Walczyk Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland

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Janusz Kopczyński Department of Surgical Pathology, Holycross Cancer Centre, Kielce, Poland

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Katarzyna Lizis-Kolus Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland

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Anna Słuszniak Laboratory of Tumor Markers, Holycross Cancer Centre, Kielce, Poland

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Janusz Słuszniak Department of Surgical Oncology, Holycross Cancer Centre, Kielce, Poland

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Tomasz Łopatyński Department of Surgery, Oncology Center of Lublin Land, Lublin, Poland

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Ryszard Mężyk Cancer Epidemiology, Holycross Cancer Centre, Kielce, Poland

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Stanisław Góźdź Oncology Clinic, Holycross Cancer Centre, Kielce, Poland
The Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland

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Aldona Kowalska Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland
The Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland

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with a postoperative diagnosis of DTC underwent the first follow-up evaluation at 4–6 weeks after TT or L surgery. The procedures included a physical examination; neck ultrasound (US) and measurement of serum thyroid-stimulating hormone (TSH), Tg and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0135
Volume/Issue:
Volume 6: Issue 7
Open access
Caiyan Mo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Tao Tong Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Ying Guo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Zheng Li Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Liyong Zhong Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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stimulating hormone receptor antibodies (TRAb) to thyroid-stimulating hormone (TSH) receptors leads to unregulated thyroid hormone production independent of pituitary TSH, resulting in hyperthyroidism ( 3 ). GD can also present with eyelid retraction

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-23-0439
Volume/Issue:
Volume 13: Issue 4
Open access
Marek Niedziela Department of Pediatric Endocrinology and Rheumatology, Institute of Pediatrics, Karol Jonscher’s Clinical Hospital, Poznan University of Medical Sciences, Poznan, Poland

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common cause being their excessive tissue concentration. Graves’ disease (GD) is a form of autoimmune hyperthyroidism associated with the presence of autoantibodies stimulating the thyroid-stimulating hormone (TSH) receptor (TRAb). Epidemiology GD

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-21-0191
Volume/Issue:
Volume 10: Issue 11
Open access
Nadia Sawicka-Gutaj Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Ariadna Zybek-Kocik Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Michał Kloska Lehigh Valley Health Network, Department of Medicine, Lehigh Valley Hospital – Cedar Crest, Allentown, USA

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Paulina Ziółkowska Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Agata Czarnywojtek Department of Pharmacology, Poznan University of Medical Sciences, Poznan, Poland

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Jerzy Sowiński Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Dorota Mańkowska-Wierzbicka Department of Gastroenterology, Internal Medicine, Metabolic Diseases and Dietetics, Poznan University of Medical Sciences, Poznan, Poland

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Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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age ≥18 years old, the elevation of TSH with a decrease of free thyroxine, and the elevation of antithyroperoxidase antibodies with features of Hashimoto’s thyroiditis in ultrasound examination of the thyroid gland. Females with decreased TSH

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0059
Volume/Issue:
Volume 10: Issue 4
Open access
Qiankai Jin Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Guoqing Huang Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Xiaoqing Tian Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Yimeng Shu Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Ximisinuer Tusongtuoheti Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Yushan Mao Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China

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between THs and MetS in the euthyroid population is still controversial. A survey of 20,053 euthyroid Korean adults found that neither serum thyroid stimulating hormone (TSH) nor free thyroxine (FT4) was significantly associated with MetS ( 6 ). Mehran et

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-22-0424
Volume/Issue:
Volume 12: Issue 5
Open access
Elena Izkhakov Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel

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Joseph Meyerovitch Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Community Division, Clalit Health Services, Tel Aviv, Israel
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petah Tikva, Israel

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Micha Barchana School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel

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Yacov Shacham Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Department of Cardiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

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Naftali Stern Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Lital Keinan-Boker School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel
National Cancer Registry, Israel Center for Disease Control, Ministry of Health, Israel, Ramat Gan, Israel

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generally consists of thyroidectomy, radioiodine ablation and treatment with levothyroxine at dosages aimed to achieve suppression of the thyroid-stimulating hormone (TSH). However, lower TSH levels in TC survivors were found to be associated with a higher

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0038
Volume/Issue:
Volume 8: Issue 4
Open access
Beibei Zhu School of Public Health, Anhui Medical University, Hefei, Anhui, China
Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China

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Yan Han School of Public Health, Anhui Medical University, Hefei, Anhui, China
Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China

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Fen Deng School of Public Health, Anhui Medical University, Hefei, Anhui, China
Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China

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Kun Huang School of Public Health, Anhui Medical University, Hefei, Anhui, China
Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China

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Shuangqin Yan Ma’anshan Maternal and Child Health Care Center, Ma’anshan, Anhui, China

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Jiahu Hao School of Public Health, Anhui Medical University, Hefei, Anhui, China
Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China

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Peng Zhu School of Public Health, Anhui Medical University, Hefei, Anhui, China
Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China

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Fangbiao Tao School of Public Health, Anhui Medical University, Hefei, Anhui, China
Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People’s Republic of China, Hefei, Anhui, China
NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China
Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, Anhui, China

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glucose abnormality have been well established. However, previous studies mainly focused on thyroid-stimulating hormone (TSH), fT4 and T4. T3 has long been overlooked, even though T3 plays a significant role in glucose regulation ( 11 ). In recent years, T

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0088
Volume/Issue:
Volume 10: Issue 7
Open access
Izabelle Lövgren Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK

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Azadeh Abravan Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK

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Abigail Bryce-Atkinson Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK

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Marcel van Herk Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK
Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK

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2 Summary of key hormones of the hypothalamic–pituitary (HP) axis, their functions, and the known consequences of their absence. (A) Thyroid-stimulating hormone (TSH) released from the pituitary gland stimulates triiodothyronine release (T 3

Article Type:
Review Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0298
Volume/Issue:
Volume 11: Issue 12
Open access
H A Booij Department of Neurology, Medisch Spectrum Twente, Enschede, the Netherlands

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W D C Gaykema Roessingh Rehabilitation Center, Enschede, the Netherlands

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K A J Kuijpers Roessingh Rehabilitation Center, Enschede, the Netherlands

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M J M Pouwels Department of Endocrinology, Medisch Spectrum Twente, Enschede, the Netherlands

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H M den Hertog Department of Neurology, Medisch Spectrum Twente, Enschede, the Netherlands

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.87 19–209 days, mean 62 ± 8 Any degree 19, GH 11.9, LH/FSH 7.1, ACTH 2.4, TSH 0 Not assessed Bondanelli, 2010 ( 7 ) Prospective cohort 56 Mean NIHSS 10.75 ± 0.55 1–3 months and 12–15 months 1–3 months: any degree 35.7, GH 30.3, LH

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0147
Volume/Issue:
Volume 7: Issue 6
Open access