Nannan Bian
Nannan Bian
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Xiaomeng Sun
Xiaomeng Sun
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Biao Zhou
Biao Zhou
Departments of General Surgery and Obesity and Metabolic Disease Center, China-Japan Friendship Hospital, Beijing, China
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Lin Zhang
Lin Zhang
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Qiu Wang
Qiu Wang
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Yu An
Yu An
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Xiaohui Li
Xiaohui Li
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Yinhui Li
Yinhui Li
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Jia Liu
Jia Liu
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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Hua Meng
Hua Meng
Departments of General Surgery and Obesity and Metabolic Disease Center, China-Japan Friendship Hospital, Beijing, China
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Guang Wang
Guang Wang
Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
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.1 kg and 0.1 cm, respectively. Venous blood samples were collected after overnight fasting for 10 to 12 h. Oral glucose tolerance test (OGTT), a 75 g oral glucose solution, was used to assess insulin sensitivity and insulin secretion function in the
Xianghe Chen
Xianghe Chen
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xinyu Zeng
Xinyu Zeng
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xiao Qiu
Xiao Qiu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Chi Liu
Chi Liu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Pengcheng Lu
Pengcheng Lu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Ziming Shen
Ziming Shen
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xiangxiang Zhou
Xiangxiang Zhou
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Kang Yang
Kang Yang
Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China
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) Fasting blood glucose. (C) Insulin levels. (D) Results of the OGTT. (E) Area under the curve of the OGTT. (F) Result of HOMA-IR. * P < 0.05, ** P < 0.01. AUC, are under the curve; OGTT, oral glucose tolerance test. Exercise improves the
Xiao-jun Zhou
Xiao-jun Zhou
Department of Endocrinology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China
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Lin Ding
Lin Ding
Department of Endocrinology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China
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Jia-xin Liu
Jia-xin Liu
Department of Endocrinology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China
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Le-qun Su
Le-qun Su
Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China
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Jian-jun Dong
Jian-jun Dong
Division of Endocrinology, Department of Medicine, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong, China
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Lin Liao
Lin Liao
Department of Endocrinology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China
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samples were obtained from the patients for laboratory tests after at least 8 h of overnight fasting. Oral glucose tolerance test (OGTT) with a 75 g glucose load was performed. Blood glucose from the fasting and 2-h postloading blood sampling was measured
Ling-Jun Li
Ling-Jun Li
Division of O&G, KK Women’s and Children’s Hospital, Singapore, Singapore
O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore
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O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore
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Izzuddin M Aris
Izzuddin M Aris
Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore, Singapore
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Lin Lin Su
Lin Lin Su
Department of O&G, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
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Yap Seng Chong
Yap Seng Chong
Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore, Singapore
Department of O&G, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
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Department of O&G, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
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Tien Yin Wong
Tien Yin Wong
O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore
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Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore
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Kok Hian Tan
Kok Hian Tan
Division of O&G, KK Women’s and Children’s Hospital, Singapore, Singapore
O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore
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O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore
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Jie Jin Wang
Jie Jin Wang
O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore
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glucose tolerance test (OGTT), glycated hemoglobin (HbA1C) and insulin level) and C-reactive protein (CRP). We applied Adults Treatment Panel (ATP) III 2000 to define postpartum MetS ( 21 ) when at least three of the four following components were met
Chenghao Piao
Chenghao Piao
Department of Radiology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China
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Xiaojie Wang
Xiaojie Wang
Department of Human Anatomy, Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China
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Shiqiao Peng
Shiqiao Peng
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province, People’s Republic of China
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Xinyu Guo
Xinyu Guo
Department of Obstetrics, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China
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Hui Zhao
Hui Zhao
Department of Laboratory Medicine, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China
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Li He
Li He
Department of Gastroenterology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China
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Yan Zeng
Yan Zeng
Department of Obstetrics, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China
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Fan Zhang
Fan Zhang
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province, People’s Republic of China
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Kewen Zhu
Kewen Zhu
Department of Human Anatomy, Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China
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Yiwei Wang
Yiwei Wang
Department of Human Anatomy, Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China
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homeostasis model assessment for insulin resistance (HOMA-IR) was calculated by the following equation: HOMA-IR = fasting glucose (mmol/L) × fasting insulin (µIU/mL)/22.5. Women from the study group during weeks 24–28 of pregnancy were given a 75-g OGTT. The
Mohammed S Albreiki
Mohammed S Albreiki
Department of Biochemistry and Physiology, Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK
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Benita Middleton
Benita Middleton
Department of Biochemistry and Physiology, Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK
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Shelagh M Hampton
Shelagh M Hampton
Department of Biochemistry and Physiology, Centre for Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK
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exogenous melatonin prior to an oral glucose tolerance test (OGTT) in the morning and evening and resulted in raised insulin and glucose responses compared to placebo ( 17 ). This study conflicts with our results; however, this may be due to differences
Jukka Koffert
Jukka Koffert
Department of Gastroenterology, Turunmaa Hospital, Turku, Finland
Turku PET Centre, University of Turku, Turku, Finland
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Turku PET Centre, University of Turku, Turku, Finland
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Henri Honka
Henri Honka
Turku PET Centre, University of Turku, Turku, Finland
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Jarmo Teuho
Jarmo Teuho
Department of Gastroenterology, Turunmaa Hospital, Turku, Finland
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Saila Kauhanen
Saila Kauhanen
Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland
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Saija Hurme
Saija Hurme
Institute of Biostatistics, University of Turku, Turku, Finland
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Riitta Parkkola
Riitta Parkkola
Turku PET Centre, University of Turku, Turku, Finland
Department of Radiology, University of Turku and Turku University Hospital, Turku, Finland
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Department of Radiology, University of Turku and Turku University Hospital, Turku, Finland
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Vesa Oikonen
Vesa Oikonen
Turku PET Centre, University of Turku, Turku, Finland
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Andrea Mari
Andrea Mari
Institute of Neuroscience, National Research Council, Padua, Italy
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Andreas Lindqvist
Andreas Lindqvist
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Nils Wierup
Nils Wierup
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Leif Groop
Leif Groop
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Pirjo Nuutila
Pirjo Nuutila
Turku PET Centre, University of Turku, Turku, Finland
Department of Endocrinology, Turku University Hospital, Turku, Finland
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Department of Endocrinology, Turku University Hospital, Turku, Finland
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measured changes in splanchnic BF and BV after a mixed-meal test, GIP infusion, and GLP-1 infusion ( Supplementary Fig. 1 , see section on supplementary data given at the end of this article). Prior to PET-studies a routine 75-g 2-h OGTT was performed to
R Solomon-Zemler
R Solomon-Zemler
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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L Basel-Vanagaite
L Basel-Vanagaite
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
Felsenstein Medical Research Center, Petach Tikva, Israel
Pediatric Genetics, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
Felsenstein Medical Research Center, Petach Tikva, Israel
Pediatric Genetics, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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D Steier
D Steier
Day Hospitalization Department, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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S Yakar
S Yakar
David B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, New York, USA
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E Mel
E Mel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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M Phillip
M Phillip
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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L Bazak
L Bazak
Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
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D Bercovich
D Bercovich
Tel-Hai College, Tel-Hai, Israel
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H Werner
H Werner
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Shalom and VardaYoran Institute for Human Genome Research, Tel Aviv University, Tel Aviv, Israel
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Shalom and VardaYoran Institute for Human Genome Research, Tel Aviv University, Tel Aviv, Israel
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L de Vries
L de Vries
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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/mL) IGF-1 (ng/mL) HbA1c % (mmol/L) Normal range 0.3–2.4 153–322 4.2–5.7 OGTT at 32 years 0′ 87 0.56 75 5.1 (32) 1 h 129 2.19 382 2 h 105 >2.32 451 3 h 89 2
A J Varewijck
A J Varewijck
Erasmus MC, Department of Internal Medicine, Division of Endocrinology, 's-Gravendijkwal 230, Room D-443, 3015 CE Rotterdam, The Netherlands
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A J van der Lely
A J van der Lely
Erasmus MC, Department of Internal Medicine, Division of Endocrinology, 's-Gravendijkwal 230, Room D-443, 3015 CE Rotterdam, The Netherlands
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S J C M M Neggers
S J C M M Neggers
Erasmus MC, Department of Internal Medicine, Division of Endocrinology, 's-Gravendijkwal 230, Room D-443, 3015 CE Rotterdam, The Netherlands
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S W J Lamberts
S W J Lamberts
Erasmus MC, Department of Internal Medicine, Division of Endocrinology, 's-Gravendijkwal 230, Room D-443, 3015 CE Rotterdam, The Netherlands
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L J Hofland
L J Hofland
Erasmus MC, Department of Internal Medicine, Division of Endocrinology, 's-Gravendijkwal 230, Room D-443, 3015 CE Rotterdam, The Netherlands
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J A M J L Janssen
J A M J L Janssen
Erasmus MC, Department of Internal Medicine, Division of Endocrinology, 's-Gravendijkwal 230, Room D-443, 3015 CE Rotterdam, The Netherlands
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patients, with active acromegaly, were enrolled. Diagnosis of active acromegaly was based on clinical presentation, unsuppressed GH levels during an oral glucose tolerance test (OGTT), and elevated age-matched total IGF1 levels (and radiological detection
Rui Zhang
Rui Zhang
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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Xinmei Huang
Xinmei Huang
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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Yue Li
Yue Li
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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Zhiyan Yu
Zhiyan Yu
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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Yueyue Wu
Yueyue Wu
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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Bingbing Zha
Bingbing Zha
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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Heyuan Ding
Heyuan Ding
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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Shufei Zang
Shufei Zang
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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Jun Liu
Jun Liu
Department of Endocrinology, Shanghai Fifth People’s Hospital affiliated to Fudan University, Minhang District, Shanghai, People’s Republic of China
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participants provided informed consent. Diabetes was confirmed by OGTT (oral glucose tolerance test) based on the diagnostic criteria recommended by the American Diabetes Association, 1997: (i) typical symptoms of diabetes (polydipsia, polyuria, polyphagia, and
