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Luca Persani Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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Biagio Cangiano Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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Marco Bonomi Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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hormones including TSH, septo-optic dysplasia and ectopic posterior pituitary   FGF8 600483 AR KS and nCHH, variable associations with defects of other pituitary hormones including TSH, holoprosencephaly and corpus callosum agenesia   FOXA

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0515
Volume/Issue:
Volume 8: Issue 2
Open access
Wouter W de Herder Section of Endocrinology, Department of Internal Medicine, Erasmus MC, 's Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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somatostatin (72, 73, 74, 75, 76, 77) . In addition to hormonal structure function investigation, Guillemin addressed the subjects of activins, inhibins and fibroblast growth factor (FGF). Guillemin was awarded numerous honours and prizes including the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-14-0070
Volume/Issue:
Volume 3: Issue 3
Open access
Athanasios Zervas Endocrine Unit, Athens Medical Centre, Athens, Greece

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George Chrousos Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, University Research Institute of Maternal and Child Health and Precision Medicine, and UNESCO Chair on Adolescent Health Care, National and Kapodistrian University of Athens, Athens, Greece
National and Kapodistrian University of Athens Medical School, ‘Aghia Sophia’ Children’s Hospital, Athens, Greece

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Sarantis Livadas Endocrine Unit, Athens Medical Centre, Athens, Greece

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regulation of GnRH secretion. Mutations in many genes can cause HH, and some of these genes are also implicated in CPHD (among them, CHD7, PROKR2, WDR11, FGFR1, and FGF8). In humans, a differentiating diagnosis between PROP1 and POU1F1 patients can be the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0615
Volume/Issue:
Volume 10: Issue 5
Open access
Barbara J Boucher Blizard Institute, Barts & The London school of Medicine & Dentistry, Queen Mary University of London, London, UK

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autocrine and paracrine functions. Renal calcitriol production is regulated by factors including parathyroid hormone, FGF23 (fibroblast growth factor 23), serum phosphate and prolactin. In other target tissues, all of which express both the activating

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0274
Volume/Issue:
Volume 9: Issue 9
Open access
Kinnaree Sorapipatcharoen Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Thipwimol Tim-Aroon Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Pat Mahachoklertwattana Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Wasun Chantratita Center for Medical Genomics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Nareenart Iemwimangsa Center for Medical Genomics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Insee Sensorn Center for Medical Genomics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Bhakbhoom Panthan Center for Medical Genomics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Poramate Jiaranai Center for Medical Genomics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Saisuda Noojarern Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Patcharin Khlairit Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Sarunyu Pongratanakul Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Chittiwat Suprasongsin Research Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Manassawee Korwutthikulrangsri Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Chutintorn Sriphrapradang Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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Preamrudee Poomthavorn Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

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hyperthyroxinemia AD ALMS1 606844 Alstrom syndrome AR DIO1 147892 Asymptomatic hyperthyroxinemia AD DIO2 601413 Asymptomatic hyperthyroxinemia ND FGF8 600483 Hypogonadotropic hypogonadism with or without anosmia AD

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0411
Volume/Issue:
Volume 9: Issue 11
Open access
Tatiana V Novoselova Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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Peter J King Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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Leonardo Guasti Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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Louise A Metherell Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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Adrian J L Clark Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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Li F Chan Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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. Determining the reason for this dissociation between high SHH and Gli1 which is unchanged as well as the co-ordination with other factors involved with capsule thickness such as FGF signalling will be investigated in the future ( Fig. 1 ). Figure 1 Model

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-19-0190
Volume/Issue:
Volume 8: Issue 7
Open access
Earn H Gan Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK
Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Wendy Robson Urology Unit, Freeman Hospital, Newcastle upon Tyne, UK

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Peter Murphy Urology Unit, Freeman Hospital, Newcastle upon Tyne, UK

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Robert Pickard Urology Unit, Freeman Hospital, Newcastle upon Tyne, UK
Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK

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Simon Pearce Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK
Endocrine Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Rachel Oldershaw Department of Musculoskeletal Biology, Institute of Ageing and Chronic disease, University of Liverpool, Liverpool, UK

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culture flask at 37°C, under an atmospheric oxygen tension of 20% and 5% CO 2 . The remaining half of the cell suspension was seeded in a MSC growth promotion medium (MGPM; alpha modified Eagle’s medium (aMEM), 10% (vol/vol) FBS, 5 ng/mL FGF2 (Sigma)), at

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0067
Volume/Issue:
Volume 7: Issue 5
Open access
Qiu-ming Yao Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Bin Wang Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Xiao-fei An Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Jin-an Zhang Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China

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Liumei Ding Department of Clinical Laboratory, Jinshan Hospital of Fudan University, Shanghai, China

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. Long-term complications of diabetes mellitus . New England Journal of Medicine 1993 328 1676 – 1685 . ( https://doi.org/10.1056/NEJM199306103282306 ) 10.1056/NEJM199306103282306 3 Gasser E Moutos CP Downes M Evans RM . FGF1 – a new weapon to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0253
Volume/Issue:
Volume 7: Issue 1
Open access
Laurent Maïmoun Département de Médecine Nucléaire, Hôpital Lapeyronie, Centre Hospitalier Régional Universitaire (CHU) Montpellier, Montpellier, France
PhyMedExp, Université de Montpellier, INSERM, CNRS, Montpellier, France

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Denis Mariano-Goulart Département de Médecine Nucléaire, Hôpital Lapeyronie, Centre Hospitalier Régional Universitaire (CHU) Montpellier, Montpellier, France
PhyMedExp, Université de Montpellier, INSERM, CNRS, Montpellier, France

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Helena Huguet Unité de Recherche Clinique et Epidémiologie, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France

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Eric Renard Departement d’Endocrinologie, Diabète, Nutrition, Hôpital Lapeyronie, CHRU Montpellier, Montpellier, France
CIC INSERM 1411, Hôpital Gui de Chauliac, CHU Montpellier, Montpellier Cedex 5, France
Institut de Génomique Fonctionnelle, CNRS UMR 5203/INSERM U661/Université Montpellier, Montpellier, France

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Patrick Lefebvre Departement d’Endocrinologie, Diabète, Nutrition, Hôpital Lapeyronie, CHRU Montpellier, Montpellier, France

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Marie-Christine Picot Unité de Recherche Clinique et Epidémiologie, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France
CIC INSERM 1411, Hôpital Gui de Chauliac, CHU Montpellier, Montpellier Cedex 5, France

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Anne-Marie Dupuy Département de Biochimie, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France

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Jean-Paul Cristol PhyMedExp, Université de Montpellier, INSERM, CNRS, Montpellier, France
Département de Biochimie, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France

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Philippe Courtet Institut de Génomique Fonctionnelle, CNRS, INSERM Université Montpellier, Montpellier, France
Département d’Urgence et Post-Urgence Psychiatrique, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France

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Vincent Boudousq Département de Médecine Nucléaire, Hôpital Carémeau, CHU Nîmes, Nîmes, France

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Antoine Avignon Département Endocrinologie, Nutrition, Diabète, Equipe Nutrition, Diabète, CHU Montpellier, Montpellier, France

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Sébastien Guillaume Institut de Génomique Fonctionnelle, CNRS, INSERM Université Montpellier, Montpellier, France
Département d’Urgence et Post-Urgence Psychiatrique, Hôpital Lapeyronie, CHU Montpellier, Montpellier, France

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Ariane Sultan PhyMedExp, Université de Montpellier, INSERM, CNRS, Montpellier, France
Département Endocrinologie, Nutrition, Diabète, Equipe Nutrition, Diabète, CHU Montpellier, Montpellier, France

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JD Smith S Brychta RJ Wang J Idelson C Perron RM Werner CD Phan GQ Kammula US Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans . Cell Metabolism 2014 19 302 – 309 . ( https://doi.org/10.1016/j

Article Type:
Research Article
Collections:
Bone and Mineral Metabolism
DOI:
https://doi.org/10.1530/EC-21-0488
Volume/Issue:
Volume 11: Issue 5
Open access
Katrine M Lauritsen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark

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Jens Hohwü Voigt Steno Diabetes Center Aarhus, Aarhus, Denmark

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Steen Bønløkke Pedersen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Troels K Hansen Steno Diabetes Center Aarhus, Aarhus, Denmark

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Niels Møller Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Niels Jessen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Biomedicine, Aarhus University, Aarhus, Denmark

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Lars C Gormsen Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark

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Esben Søndergaard Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark

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Osataphan S Macchi C Singhal G Chimene-Weiss J Sales V Kozuka C Dreyfuss JM Pan H Tangcharoenpaisan Y Morningstar J SGLT2 inhibition reprograms systemic metabolism via FGF21-dependent and -independent mechanisms . JCI Insight 2019 4 e

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-21-0558
Volume/Issue:
Volume 11: Issue 4
Open access