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Selma Flora Nordqvist Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark

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Victor Brun Boesen Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark

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Åse Krogh Rasmussen Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark

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Ulla Feldt-Rasmussen Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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Laszlo Hegedüs Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Steen Joop Bonnema Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Per Karkov Cramon Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark

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Torquil Watt Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Department of Internal Medicine, Herlev Gentofte Hospital, Copenhagen, Denmark

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Mogens Groenvold Department of Public Health, University of Copenhagen, Copenhagen, Denmark
Department of Palliative Medicine, Bispebjerg Hospital, Copenhagen, Denmark

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Jakob Bue Bjorner Department of Public Health, University of Copenhagen, Copenhagen, Denmark
National Research Centre for the Working Environment, Copenhagen, Denmark
QualityMetric Incorporated, LLC, Johnston, Rhode Island, USA

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their overall quality of life, after having responded to each of the corresponding ThyPRO scales. The Global Rating of Change questions were: ‘Compared to the last time you answered this questionnaire, do you feel that your [relevant issue, e

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0026
Volume/Issue:
Volume 10: Issue 3
Open access
Irfan Vardarli Department of Medicine I, Klinikum Vest, Knappschaftskrankenhaus Recklinghausen, Academic Teaching Hospital, Ruhr-University Bochum, Recklinghausen, Germany

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Manuel Weber Department of Nuclear Medicine, University Hospital Essen, Essen, Germany

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Frank Weidemann Department of Medicine I, Klinikum Vest, Knappschaftskrankenhaus Recklinghausen, Academic Teaching Hospital, Ruhr-University Bochum, Recklinghausen, Germany

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Dagmar Führer Department of Endocrinology, Diabetes and Metabolism, Clinical Chemistry – Division of Laboratory Research; Endocrine Tumor Center at WTZ/Comprehensive Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

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Ken Herrmann Department of Nuclear Medicine, University Hospital Essen, Essen, Germany

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Rainer Görges Department of Nuclear Medicine, University Hospital Essen, Essen, Germany

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Matias J Proenca H Bugalho MJ Calcitonin screening in nodular thyroid disease: is there a definitive answer? European Thyroid Journal 2019 8 79 – 82 . ( https://doi.org/10.1159/000494834 ) 50 Mian C Perrino M Colombo C Cavedon E

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0030
Volume/Issue:
Volume 10: Issue 3
Open access
Ali Abbara Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

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Sophie Clarke Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

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Pei Chia Eng Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK

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James Milburn Imperial College Healthcare NHS Trust, London, UK

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Devavrata Joshi Imperial College Healthcare NHS Trust, London, UK

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Alexander N Comninos Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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Rozana Ramli Imperial College Healthcare NHS Trust, London, UK

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Amrish Mehta Imperial College Healthcare NHS Trust, London, UK

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Brynmor Jones Imperial College Healthcare NHS Trust, London, UK

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Florian Wernig Imperial College Healthcare NHS Trust, London, UK

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Ramesh Nair Imperial College Healthcare NHS Trust, London, UK

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Nigel Mendoza Imperial College Healthcare NHS Trust, London, UK

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Amir H Sam Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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Emma Hatfield Imperial College Healthcare NHS Trust, London, UK

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Karim Meeran Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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Waljit S Dhillo Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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Niamh M Martin Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK

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diagnosis and management. We support the need for a prospective randomised clinical trial to try to better answer the question as to when surgery or conservative management is most appropriate. As apoplexy is such a rare condition, this will only be possible

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0255
Volume/Issue:
Volume 7: Issue 10
Open access
Emmi Naskali Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

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Katja Dettmer Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

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Peter J Oefner Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

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Pedro A B Pereira Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland

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Kai Krohn Clinical Research Institute HUCH Ltd, Biomedicum Helsinki 1, Helsinki, Finland

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Petri Auvinen Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland

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Annamari Ranki Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

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Nicolas Kluger Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

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70.3%). One questionnaire was anonymous and one patient answered only the GI-related questions. Assay of autoantibodies Serum circulating Aabs against recombinant AADC (Biosite, Täby, Sweden), TPH-1 (Sino Biological Inc., Beijing, China) and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0513
Volume/Issue:
Volume 8: Issue 1
Open access
Kaisu Luiro Department of Obstetrics and Gynecology, Reproductive Medicine Unit, Helsinki University Hospital and University of Helsinki, Helsinki, Finland

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Kristiina Aittomäki Department of Medical Genetics, Helsinki University Hospital, Helsinki, Finland

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Pekka Jousilahti Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland

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Juha S Tapanainen Department of Obstetrics and Gynecology, Reproductive Medicine Unit, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
Department of Obstetrics and Gynecology, University of Oulu and Oulu University Hospital, Medical Research Center, PEDEGO Research Unit, Oulu, Finland

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: desire, arousal, lubrication, orgasm, satisfaction and pain. Each domain is scored on a scale of 0–5, with higher scores indicating better function. One subject declined answering the FSFI. The mean FSFI score was 17.5/36 (range 1.5–32.8). Of the FSHRO

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0244
Volume/Issue:
Volume 8: Issue 10
Open access
Cornelia Then Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munich, Germany
Clinical Cooperation Group Diabetes, LMU München and Helmholtz Zentrum München, Munich, Germany

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Holger Then Freie Waldorfschule Augsburg, Augsburg, Germany

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Andreas Lechner Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munich, Germany
Clinical Cooperation Group Diabetes, LMU München and Helmholtz Zentrum München, Munich, Germany
German Center for Diabetes Research (DZD), München-Neuherberg, Germany

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Cornelia Huth German Center for Diabetes Research (DZD), München-Neuherberg, Germany
Institute of Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health (GmbH), Neuherberg, Germany

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Christa Meisinger Independent Research Group Clinical Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health (GmbH), Neuherberg, Germany
Chair of Epidemiology at UNIKAT Augsburg, Ludwig-Maximilians-Universität München, Munich, Germany

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Margit Heier Institute of Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health (GmbH), Neuherberg, Germany
KORA Study Center, University Hospital Augsburg, Augsburg, Germany

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Annette Peters German Center for Diabetes Research (DZD), München-Neuherberg, Germany
Institute of Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health (GmbH), Neuherberg, Germany
DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany

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Wolfgang Koenig DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany
Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany
Deutsches Herzzentrum München, Technische Universität München, Munich, Germany

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Wolfgang Rathmann Institute of Biometrics and Epidemiology, German Diabetes Center, Leibniz Institute at Heinrich Heine University Düsseldorf, Düsseldorf, Germany

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Christian Herder German Center for Diabetes Research (DZD), München-Neuherberg, Germany
Institute of Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

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Michael Roden German Center for Diabetes Research (DZD), München-Neuherberg, Germany
Institute of Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

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Jürgen Scherberich Klinikum München-Harlaching, Teaching Hospital of the Ludwig-Maximilians-Universität, Munich, Germany

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Jochen Seissler Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munich, Germany
Clinical Cooperation Group Diabetes, LMU München and Helmholtz Zentrum München, Munich, Germany

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separate questions concerning leisure time sport activity in winter and in summer (cycling included). Possible answers were (1) >2 h, (2) 1–2 h, (3) <1 h and (4) none per week. Participants who had a total score <5, obtained by summing the numbers (1

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0352
Volume/Issue:
Volume 8: Issue 10
Open access
Marieke Stientje Velema Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Aline de Nooijer Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Ad R M M Hermus Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Henri J L M Timmers Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Jacques W M Lenders Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands
Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technical University Dresden, Dresden, Germany

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Olga Husson Division of Clinical Studies, Institute of Cancer Research, London, UK

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Jaap Deinum Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands
Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technical University Dresden, Dresden, Germany

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with the other scales was lower than the correlation with the corresponding scale. When both criteria were met, we concluded that there was scaling fulfillment ( 20 ). For the summed (scale) scores, all answers of the items contributing to the scale

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0026
Volume/Issue:
Volume 8: Issue 4
Open access
Lukas Engler Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Christian Adolf Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Daniel A Heinrich Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Anna-Katharine Brem Max-Planck-Institute of Psychiatry, Munich, Germany
Division of Interventional Cognitive Neurology, Department of Neurology, Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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Anna Riester Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Anna Franke Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Felix Beuschlein Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Martin Reincke Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Axel Steiger Max-Planck-Institute of Psychiatry, Munich, Germany

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Heike Künzel Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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significance. Questionnaires that were incompletely answered or had missing values were excluded from further analysis. Results Basic clinical data All patients displayed elevated 24-h mean blood pressure (BP) values for both systolic and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0043
Volume/Issue:
Volume 8: Issue 4
Open access
M P Schuijt Department of Laboratory Medicine, Slingeland Hospital, Doetinchem, The Netherlands
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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C G J Sweep Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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R van der Steen Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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A J Olthaar Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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N M M L Stikkelbroeck Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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H A Ross Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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A E van Herwaarden Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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groups to calculate free testosterone by the formula of Vermeulen et al. ( 13 ) and by Ross et al. ( 21 ) and to investigate whether or not calculation of free testosterone yields results differing from those obtained by ED-LC-MS/MS. This will answer

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0110
Volume/Issue:
Volume 8: Issue 6
Open access
Göran Oleröd Department of Clinical Chemistry and Transfusion Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Lillemor Mattsson Hultén Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden

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Ola Hammarsten Department of Clinical Chemistry and Transfusion Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Eva Klingberg Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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stated that they were in full physical health and answered questionnaires regarding medication, smoking habits, physical activity, sunbed use and sun holidays during the previous month. A sun holiday was defined as a journey to a location south of the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0078
Volume/Issue:
Volume 6: Issue 2
Open access