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J Brossaud Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France

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V Pallet Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France

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J-B Corcuff Université de Bordeaux, Nutrition et Neurobiologie Intégrée, Bordeaux, France
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France

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adipocytes . Journal of Nutrition 2008 138 1004 – 1009 . 10.1093/jn/138.6.1004 95 Iacobazzi V Convertini P Infantino V Scarcia P Todisco S Palmieri F. Statins, fibrates and retinoic acid upregulate mitochondrial acylcarnitine

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Eva O Melin Department of Clinical Sciences, Endocrinology and Diabetes, Lund University, Lund, Sweden
Department of Research and Development, Växjö, Sweden
Primary Care, Växjö, Sweden

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Jonatan Dereke Department of Clinical Sciences Lund, Diabetes Research Laboratory, Lund University, Lund, Sweden

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Maria Thunander Department of Clinical Sciences, Endocrinology and Diabetes, Lund University, Lund, Sweden
Department of Research and Development, Växjö, Sweden
Department of Internal Medicine, Endocrinology and Diabetes, Central Hospital, Växjö, Sweden

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Magnus Hillman Department of Clinical Sciences Lund, Diabetes Research Laboratory, Lund University, Lund, Sweden

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and insulin resistance. Lipid-lowering drugs (LLD) were hydroxy-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors (statins) (C10AA). Indications for LLD were TC >4.5 mmol/L (>1.74 mg/dL) and/or LDL >2.5 mmol/L (>97 mg/dL) according to local

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Espen Nordheim Department of Transplantation Medicine, Section of Nephrology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Faculty of Medicine, University of Oslo, Oslo, Norway

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Trond Geir Jenssen Department of Transplantation Medicine, Section of Nephrology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Faculty of Medicine, University of Oslo, Oslo, Norway
Metabolic and Renal Research Group, Faculty of Health Sciences, UiT- The Arctic University of Norway, Tromsø

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diabetes A comprehensive care is recommended for the management of diabetes patients in the recent KDIGO clinical practice guidelines ( 21 ), including statins to all patients with diabetes and kidney disease regardless of cholesterol levels to prevent

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Jan Kvasnička 3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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Ondřej Petrák 3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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Tomáš Zelinka 3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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Judita Klímová 3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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Barbora Kološová 3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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Květoslav Novák Department of Urology, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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David Michalský 1st Department of Surgery, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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Jiří Widimský Jr 3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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Robert Holaj 3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic

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Angiotensin receptor blockers ( n (%)) 4 (17) 1 (4) NS α-blockers ( n (%)) 8 (33) 0 (0) <0.005 Central agonists ( n (%)) 2 (8) 0 (0) NS Aldosterone antagonists ( n (%)) 1 (4) 0 (0) NS Statins ( n (%)) 8

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Christian Trummer Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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Stefan Pilz Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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Verena Schwetz Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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Barbara Obermayer-Pietsch Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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Elisabeth Lerchbaum Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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cardiovascular risk 62 ± 11 years OR 2.47 (1.55–3.93) for men with 25(OH)D <25 nmol/L compared to >75 nmol/L ↑TT, ↑FAI ↓SHBG Age, BMI, wine consumption, smoking, beta-blocker use, statin use and diabetes Heijboer et al . ( 86 ) 183 men (101 men

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Qian Deng Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Yue Zhu Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Mengmeng Zhang Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Aihua Fei Department of Endocrinology, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China

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Jiaqi Liang Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Jinjin Zheng Graduate College of Anhui University of Chinese Medicine, Hefei, China

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Qingping Zhang College of Acupuncture-moxibustion and Tuina, Anhui University of Chinese Medicine, Hefei, China

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Tong Cheng Department of Geriatrics, Zhongshan Hospital, Fudan University, Shanghai, China

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Xia Ge Department of Endocrinology, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China

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statins and fibrates in the management of cardiovascular risk . Current Opinion in Lipidology 2009 20 505– 511 . ( https://doi.org/10.1097/MOL.0b013e328332e9ef ) 105 Xu N Wang Q Jiang S Wang Q Hu W Zhou S Zhao L Xie L Chen J Wellstein

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E T Aristizabal Prada Department of Internal Medicine IV, Campus Grosshadern, University-Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany

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C J Auernhammer Department of Internal Medicine IV, Campus Grosshadern, University-Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany

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well as several other drugs like phenformin, resveratrol, berberine, statins, epigallocatechin gallate and capsaicin, have been suggested to exert anti-tumoural effects by activation of AMPK and inhibition of mTOR ( 93 ). In the human NET cell lines

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