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Huiyuan Zhai Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China

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Dongxu Wang Department of Geriatrics, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China

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Yong Wang Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China

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Hongwei Gu Central Laboratory, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China

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Juan Jv Department of Cardiology, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China

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Liangliang Yuan Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China

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Chao Wang Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China

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Leiyao Chen Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China

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International 2020 2020 4532482 . ( https://doi.org/10.1155/2020/4532482 ) 29 Li N Yin L Shang J Liang M Liu Z Yang H Qiang G Du G & Yang X . Kaempferol attenuates nonalcoholic fatty liver disease in type 2 diabetic mice via the Sirt1/AMPK

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Lars Peter Sørensen
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Tina Parkner Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Esben Søndergaard
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Bo Martin Bibby Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Holger Jon Møller Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Søren Nielsen
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VAT and SAT macrophage numbers between the groups. At the same time, the VAT macrophage number was positively associated with fasting glucose, insulin, TG, liver transaminases, and histopathological components of non-alcoholic fatty liver disease

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Chun-feng Lu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Xiao-qin Ge Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Yan Wang Department of Geriatrics, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Jian-bin Su Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Xue-qin Wang Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Dong-mei Zhang Clinical Medicine Research Center, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Feng Xu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Wang-shu Liu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Min Su Department of Endocrinology, Nantong Hospital of Traditional Chinese Medicine, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, China

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), non-alcoholic fatty liver disease (NAFLD) ( 31 ) and use of insulin ( 29 ) as potential risk factors for prolonged QTc interval in type 2 diabetic patients. In agreement with previous studies, the present study constructed univariate analysis and

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Jie Shi Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Zhen Yang Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Yixin Niu Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Weiwei Zhang Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Ning Lin Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Xiaoyong Li Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Hongmei Zhang Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Hongxia Gu Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Jie Wen Department of Endocrinology and Metabolism, Institute of Endocrinology and Diabetes, Huashan Hospital, Fudan University, Shanghai, China

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Guang Ning Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrinology and Metabolism, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Li Qin Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Qing Su Department of Endocrinology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

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C Liu G Niu Y Zhang W Lu S Li X Zhang H Ning G Fan J , et al . Plasma selenium levels and nonalcoholic fatty liver disease in Chinese adults: a cross-sectional analysis . Scientific Reports 2016 6 37288 . ( https://doi.org/10

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Esben S Lauritzen The Medical Research Laboratories, Institute of Clinical Research, Aarhus University, Aarhus C, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus C, Denmark

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Nikolaj Rittig The Medical Research Laboratories, Institute of Clinical Research, Aarhus University, Aarhus C, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus C, Denmark

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Ermina Bach The Medical Research Laboratories, Institute of Clinical Research, Aarhus University, Aarhus C, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus C, Denmark

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Niels Møller The Medical Research Laboratories, Institute of Clinical Research, Aarhus University, Aarhus C, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus C, Denmark

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Mette Bjerre The Medical Research Laboratories, Institute of Clinical Research, Aarhus University, Aarhus C, Denmark

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21 in obesity and nonalcoholic fatty liver disease . Gastroenterology 2010 139 456 – 463 . ( doi:10.1053/j.gastro.2010.04.054 ) 15 Zhang X Yeung DC Karpisek M Stejskal D Zhou ZG Liu F Wong RL Chow WS Tso AW

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Shane M Regnier Committee on Molecular Metabolism and Nutrition, Chicago, Illinois, USA
Pritzker School of Medicine, Chicago, Illinois, USA
University of Chicago, Chicago, Illinois, USA

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Andrew G Kirkley University of Chicago, Chicago, Illinois, USA
Committee on Molecular Pathogenesis and Molecular Medicine, Chicago, Illinois, USA

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Daniel Ruiz Committee on Molecular Metabolism and Nutrition, Chicago, Illinois, USA
University of Chicago, Chicago, Illinois, USA

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Wakanene Kamau University of Chicago, Chicago, Illinois, USA

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Qian Wu Wadsworth Center, New York Department of Health, Albany, New York, USA

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Kurunthachalam Kannan Wadsworth Center, New York Department of Health, Albany, New York, USA

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Robert M Sargis Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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approximately 50% projected to be obese by 2030 ( 2 ). Obesity is a major risk factor for the development of cardiovascular disease, obstructive sleep apnea and nonalcoholic fatty liver disease ( 3 , 4 ), and the societal expansion in fat mass is thought to

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Hong-Fa Yan College of Life and Health Sciences, Northeastern University, Shenyang, China

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Zhao-Yu Liu College of Life and Health Sciences, Northeastern University, Shenyang, China

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Zhi-Ang Guan College of Life and Health Sciences, Northeastern University, Shenyang, China

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Chuang Guo College of Life and Health Sciences, Northeastern University, Shenyang, China

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.2010) 17 Valenti L Fracanzani AL Dongiovanni P Bugianesi E Marchesini G Manzini P Vanni E Fargion S. Iron depletion by phlebotomy improves insulin resistance in patients with nonalcoholic fatty liver disease and hyperferritinemia: evidence from a case

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Qiankai Jin Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Guoqing Huang Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Xiaoqing Tian Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Yimeng Shu Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Ximisinuer Tusongtuoheti Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China

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Yushan Mao Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China

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-to-moderate alcohol consumption is associated with increased risk of type 2 diabetes in individuals with nonalcoholic fatty liver disease: a nine-year cohort study . American Journal of Gastroenterology 2020 115 876 – 884 . ( https://doi.org/10.14309/ajg

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Yael Sofer Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv-Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Nava Nevo Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel

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Michal Vechoropoulos Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv-Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Gabi Shefer Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv-Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Etty Osher Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv-Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Nathan Landis Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv-Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Karen Tordjman
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Geoffrey L Hammond Departments of Cellular & Physiological Sciences and Obstetrics & Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada

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Naftali Stern Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv-Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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.2337/dbib9-1788 ) 10.2337/dc09-1788 20368409 22 Jaruvongvanich V Sanguankeo A Riangwiwat T Upala S. Testosterone, sex hormone-binding globulin and nonalcoholic fatty liver disease: a systematic review and meta-analysis . Annals of

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Clemens Kamrath Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany

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Alexander Eckert German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany

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Birgit Rami-Merhar Department of Pediatrics and Adolescent Medicine, Medical University Vienna, Vienna, Austria

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Sebastian Kummer Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich Heine University, Medical Faculty, Duesseldorf, Germany

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Martin Wabitsch Center for Rare Endocrine Diseases, Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Centre, Ulm, Germany

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Katharina Laubner Division of Endocrinology and Diabetology, Department of Medicine II, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany

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Florian Kopp Forth Clinical Department of Medicine, Academic Teaching Hospital Augsburg, Augsburg, Germany

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Silvia Müther Center for Pediatric Diabetology, DRK-Kliniken-Berlin Westend, Berlin, Germany

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Steffen Mühldorfer Department for Gastroenterology, Endocrinology and Metabolic Diseases, Bayreuth University Hospital, Friedrich-Alexander University Erlangen-Nuremberg, Bayreuth, Germany

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Reinhard W Holl German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
Institute of Epidemiology and Medical Biometry, ZIBMT, Ulm University, Ulm, Germany

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lipodystrophy. LDs lead to insulin resistance and further complications such as diabetes mellitus, hypertriglyceridemia, nonalcoholic fatty liver disease (NAFLD), polycystic ovarian syndrome, and acanthosis nigricans. The prevalence of generalized

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