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Xingrong Tan Department of Endocrinology, 9th People’s Hospital of Chongqing, Beibei City, Chongqong, China

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Wenjing Hu Chongqing Prevention and Treatment Hospital for Occupational Diseases, Chongqing, China

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Shan Yang Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China

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Han Dai Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China

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Shangcheng Xu Chongqing Prevention and Treatment Hospital for Occupational Diseases, Chongqing, China

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Gangyi Yang Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China

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Ling Li Department of Endocrinology, 9th People’s Hospital of Chongqing, Beibei City, Chongqong, China

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Shiguo Tang Department of Endocrinology, 9th People’s Hospital of Chongqing, Beibei City, Chongqong, China

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Yi Wang Department of Endocrinology, 9th People’s Hospital of Chongqing, Beibei City, Chongqong, China

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.1155/2014/323407 ) 28 Choi YK Kim MK Bae KH Seo HA Jeong JY Lee WK Kim JG Lee IK Park KG Serum irisin levels in new-onset type 2 diabetes . Diabetes Research and Clinical Practice 2013 100 96 – 101 . ( https://doi.org/10.1016/j.diabres.2013

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Run-Qing Xiong Department of Ultrasonic Imaging, Xiamen Medical College Affiliated Second Hospital, Fujian, China

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Yan-Ping Li Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Fujian, China

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Lu-Ping Lin Department of Endocrinology, Xiamen Medical College Affiliated Second Hospital, Fujian, China

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Jeng-Yuan Yao Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Fujian, China

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Introduction Diabetes mellitus, particularly type 2 diabetes mellitus (T2DM), is a global health issue affecting millions of individuals worldwide, with its prevalence continually escalating ( 1 ). T2DM is associated with a multitude of

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Jairo Arturo Pinzón-Cortés Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia
School of Medicine, Universidad de los Andes, Bogotá, Colombia

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Angelina Perna-Chaux Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

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Nicolás Steven Rojas-Villamizar Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

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Angélica Díaz-Basabe Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

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Diana Carolina Polanía-Villanueva Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

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María Fernanda Jácome Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia

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Carlos Olimpo Mendivil School of Medicine, Universidad de los Andes, Bogotá, Colombia
Endocrinology Section, Hospital Universitario Fundación Santa Fe de Bogotá, Bogotá, Colombia

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Helena Groot Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia
School of Medicine, Universidad de los Andes, Bogotá, Colombia

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Valeriano López-Segura Biological Sciences Department, Laboratory of Human Genetics, Universidad de los Andes, Bogotá, Colombia
School of Medicine, Universidad de los Andes, Bogotá, Colombia

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diabetes was estimated at 381 million. Projections from the International Diabetes Federation predict that by the year 2030, most growth in new diabetes cases will come from developing countries, where a prevalence increase of 69% is expected ( 2 ). The

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Hauke Thomsen Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany
Center for Primary Health Care Research, Lund University, Malmö, Sweden
GeneWerk GmbH, Heidelberg, Germany

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Xinjun Li Center for Primary Health Care Research, Lund University, Malmö, Sweden

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Kristina Sundquist Center for Primary Health Care Research, Lund University, Malmö, Sweden
Departments of Family Medicine and Community Health, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Center for Community-based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Shimane, Japan

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Jan Sundquist Center for Primary Health Care Research, Lund University, Malmö, Sweden
Departments of Family Medicine and Community Health, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Center for Community-based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Shimane, Japan

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Asta Försti Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany
Center for Primary Health Care Research, Lund University, Malmö, Sweden
Hopp Children’s Cancer Center (KiTZ), Heidelberg, Germany
Division of Pediatric Neurooncology, German Cancer Research Centre (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany

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Kari Hemminki Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany
Center for Primary Health Care Research, Lund University, Malmö, Sweden
Division of Cancer Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany
Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic

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autoantibodies ( 4 , 5 ). AD is part of the rare juvenile APS-1, which is usually diagnosed before age 15 years and is caused by recessive mutations in the autoimmune regulatory gene (AIRE) ( 4 , 5 ). The more common adult-onset APS-2 is defined through co

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Thozhukat Sathyapalan Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, UK

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Anne-Marie Coady Department of Obstetric Ultrasound, Hull and East Yorkshire Women’s and Children’s Hospital, Hull, UK

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Eric S Kilpatrick Department of Clinical Biochemistry, Sidra Medical and Research Center, Doha, Qatar

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Stephen L Atkin Department of Medicine, Weill Cornell Medical College, Doha, Qatar

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-analysis . Diabetes Care 2009 32 1924 – 1929 . ( doi:10.2337/dbib9-0738 ) 19794004 10.2337/dc09-0738 5 Waters DD Ho JE DeMicco DA Breazna A Arsenault BJ Wun CC Kastelein JJ Colhoun H Barter P. Predictors of new-onset

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Yusaku Mori Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Department of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Shinagawa, Tokyo, Japan

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Eunhyoung Ko Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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Rudolf Furrer Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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Linda C Qu Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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Stuart C Wiber Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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I George Fantus Departments of Medicine and Physiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada
Division of Endocrinology and Metabolism, Leadership Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada

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Mario Thevis Center for Preventive Doping Research and Institute of Biochemistry, German Sport University Cologne, Cologne, Germany

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Alan Medline Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada
Department of Pathology, Humber River Regional Hospital, Toronto, Ontario, Canada

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Adria Giacca Departments of Physiology and Medicine, Institute of Medical Science, Banting and Best Diabetes Centre, University of Toronto, Toronto, Ontario, Canada

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Introduction Insulin treatment is life saving for type 1 diabetes and essential for achieving glycaemic control and thus preventing complications in type 2 diabetes. However, insulin has mitotic properties in addition to its well

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Riying Liang Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China
Department of Ultrasound, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China

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Meijun Wang Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Chang Fu Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Hua Liang Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Hongrong Deng Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Ying Tan Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Fen Xu Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Mengyin Cai Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Investigators. Liraglutide and renal outcomes in Type 2 diabetes. New England Journal of Medicine 2017 377 . ( https://doi.org/10.1056/NEJMoa1616011 ) 13 Muskiet MHA Tonneijck L Smits MM van Baar MJB Kramer MHH Hoorn EJ Joles JA

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Li Qian Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

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Yuxiao Zhu Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

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Yan Luo Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

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Mu Zhang Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

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Liping Yu Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA

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Yu Liu Department of Endocrinology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

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Tao Yang Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

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Introduction Type 1 diabetes mellitus (T1DM) is well-defined as one of the most common and lifelong autoimmune diseases characterized by pancreatic β-cell destruction ( 1 , 2 ). Several autoantibodies, such as glutamic acid decarboxylase

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Lei Lei Department of Nephrology, The Second Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, China

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Yi-Hua Bai Department of Nephrology, The Second Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, China

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Hong-Ying Jiang Department of Nephrology, The Second Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, China

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Ting He Department of Nephrology, The Second Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, China

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Meng Li Department of Nephrology, The Second Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, China

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Jia-Ping Wang Department of Radiology, The Second Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, China

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diabetes (T2D) has rapidly increased over the recent decades, and T2D has become a leading public health challenge ( 5 ). Therefore, it is urgent to explore new therapeutic methods for T2D. Moreover, recent research reported that m6A content was decreased

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Chenghao Piao Department of Radiology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China

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Xiaojie Wang Department of Human Anatomy, Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China

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Shiqiao Peng Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province, People’s Republic of China

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Xinyu Guo Department of Obstetrics, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China

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Hui Zhao Department of Laboratory Medicine, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China

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Li He Department of Gastroenterology, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China

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Yan Zeng Department of Obstetrics, The Second Affiliated Hospital of Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China

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Fan Zhang Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, Shenyang City, Liaoning Province, People’s Republic of China

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Kewen Zhu Department of Human Anatomy, Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China

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Yiwei Wang Department of Human Anatomy, Shenyang Medical College, Shenyang City, Liaoning Province, People’s Republic of China

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intolerance of diverse severity with onset or first validation during pregnancy ( 2 ). It is one of the most common gestational complications and affects approximately 25% of all pregnant women. GDM is of high risk for mothers and new-borns and results in an

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