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' thyroiditis, anti-thyroid autoantibodies as well as interleukin-6 (IL-6) levels. Table 1 Prevalence of thyroid hormone abnormalities in patients with COVID-19 and controls in recently published studies. Month Author Design n Population
Department of Endocrinology and Diabetes, Pakistan Kidney and Liver Institute and Research Centre, Knowledge City, Lahore, Pakistan
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requires clarification and confirmation. The assessment of additional markers indicative of endothelial function and systemic inflammation (endothelin-1, angiotensin II, ROS, TNF (TNF-a) or interleukin (IL)-1 or 6) were not performed as part of this study
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Introduction Smoking ( 1 ), low physical activity ( 2 ), obesity, insulin resistance and hyperglycemia ( 3 ) are independently associated with incident type 2 diabetes mellitus (T2DM). Insulin resistance is affected by metabolic risk factors
Department of Rheumatology and Clinical Immunology, Charité-University Medicine, Berlin, Germany
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Bone Research Program, ANZAC Research Institute, University of Sydney, Sydney, NSW, Australia
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Key Laboratory for Space Bioscience and Biotechnology, Institute of Special Environmental Biophysics, School of Life Sciences, Northwestern Polytechnical University, Shaanxi, China
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Concord Clinical School, The University of Sydney, Sydney, Australia
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Concord Clinical School, The University of Sydney, Sydney, Australia
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Concord Clinical School, The University of Sydney, Sydney, Australia
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Background Acute inflammation is typically associated with an activation of the hypothalamo-pituitary-adrenal (HPA) axis, which results in an increase in the level of glucocorticoids within the circulation ( 1 ). In situations where this
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and destructive action of interleukin 1 β (IL1B) in human osteoarthritic cartilage samples (9) and in rabbit articular chondrocytes (10) . Our group has reported that chronic arthritis decreases Pparα expression in liver and gastrocnemius, whereas
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Introduction Diabetes is a global health concern owing to its high prevalence and related health problems ( 1 ). Type 2 diabetes mellitus is caused by a combination of genetic and environmental factors and is also recognized as a chronic, low
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the inhibition of TGF-β1/connective tissue growth factor pathway mediated by interleukin 6 in the kidney of T2DM mice. Activation or inhibition of these signaling pathways reduced renal interstitial ECM deposition and improved renal interstitial
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infiltrated in adipose fat pads Macrophages infiltrated in distinct adipose fat pads are recognized to produce several interleukins that are able to cause insulin resistance ( 17 ). Adipose tissue macrophages (ATM) can assume two distinct phenotypes, the M1
CEB – Centro de Engenharia Biológica, Universidade do Minho, Braga, Portugal
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CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde & Instituto Universitário de Ciências da Saúde, Gandra, Portugal
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Driel M Hazes JMW van Leeuwen JPTM Lubberts E 1,25-Dihydroxyvitamin D3 modulates Th17 polarization and interleukin-22 expression by memory T cells from patients with early rheumatoid arthritis . Arthritis and Rheumatism 2010 62 132 – 142
Musculoskeletal Research Laboratory and Bone Quality and Health Assessment Centre, Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong
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Department of Endocrinology, The First Affiliated Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
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pachydermia. Accompanying abnormalities include sebaceous hyperplasia, hyperhidrosis, acro-osteolysis, and effusions and pain of large joints ( 1 , 2 ). Additional developmental anomalies, seen in a proportion of PHO patients, include patent ductus arteriosus