Hong Tang
Hong Tang
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Xiaomei Jiang
Xiaomei Jiang
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Yu Hua
Yu Hua
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Heyue Li
Heyue Li
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Chunlan Zhu
Chunlan Zhu
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Xiaobai Hao
Xiaobai Hao
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Minhui Yi
Minhui Yi
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Linxia Li
Linxia Li
Departments of Gynaecology and Obstetrics Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
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-resistant hyperinsulinism and androgen alter the function of granulosa cells (GCs) ( 6 , 7 ). GCs play a key role in the maturation and ovulation of oocytes. Recently, studies have reported that oxidative stress and oxidative stress-induced cell death in GCs are associated
Sarah J Hall
Sarah J Hall
Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia
Bushfire and Natural Hazards Cooperative Research Centre, East Melbourne, Victoria, Australia
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Bushfire and Natural Hazards Cooperative Research Centre, East Melbourne, Victoria, Australia
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Brad Aisbett
Brad Aisbett
Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia
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Samuel J Robertson
Samuel J Robertson
Institute of Sport, Exercise & Active Living (ISEAL), Victoria University, Footscray, Victoria, Australia
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Sally A Ferguson
Sally A Ferguson
Appleton Institute, School of Health, Medical and Applied Sciences, Central Queensland University, Adelaide, South Australia, Australia
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Anne I Turner
Anne I Turner
Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia
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in higher subjective stress levels than when not on-call ( 1 , 12 , 13 , 14 , 15 , 16 ). Despite this, few studies have investigated the physiological stress response to operating on-call from home ( 1 , 17 , SJ Hall, AI Turner, SA Ferguson, SJ
Qian Deng
Qian Deng
Graduate College of Anhui University of Chinese Medicine, Hefei, China
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Yue Zhu
Yue Zhu
Graduate College of Anhui University of Chinese Medicine, Hefei, China
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Mengmeng Zhang
Mengmeng Zhang
Graduate College of Anhui University of Chinese Medicine, Hefei, China
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Aihua Fei
Aihua Fei
Department of Endocrinology, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China
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Jiaqi Liang
Jiaqi Liang
Graduate College of Anhui University of Chinese Medicine, Hefei, China
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Jinjin Zheng
Jinjin Zheng
Graduate College of Anhui University of Chinese Medicine, Hefei, China
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Qingping Zhang
Qingping Zhang
College of Acupuncture-moxibustion and Tuina, Anhui University of Chinese Medicine, Hefei, China
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Tong Cheng
Tong Cheng
Department of Geriatrics, Zhongshan Hospital, Fudan University, Shanghai, China
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Xia Ge
Xia Ge
Department of Endocrinology, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China
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ferroptosis ( 10 , 11 , 12 ). Hyperglycemia leads to the overproduction of reactive oxygen species (ROS) and subsequently enhances oxidative stress. The increased HG and lipid ROS production, which were closely associated with pancreatic islet beta cell
Tsung-Hui Wu
Tsung-Hui Wu
Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Guan-Yu Su
Guan-Yu Su
Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Tsung-Yun Liu
Tsung-Yun Liu
Institute of Food Safety and Health Risk Assessment, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan
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Hsiang-Tsui Wang
Hsiang-Tsui Wang
Institute of Food Safety and Health Risk Assessment, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan
Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
PhD Program in Toxicology, Kaohsiung Medical University, Kaohsiung, Taiwan
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Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
PhD Program in Toxicology, Kaohsiung Medical University, Kaohsiung, Taiwan
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Chii-Min Hwu
Chii-Min Hwu
Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Faculty of Medicine, National Yang Ming Chiao Tung University School of Medicine, Taipei, Taiwan
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Faculty of Medicine, National Yang Ming Chiao Tung University School of Medicine, Taipei, Taiwan
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effects through various mechanisms, including DNA and protein adduction, disruption of mitochondria and endoplasmic reticulum, cell membrane damage, oxidative stress, and inflammation and immune dysfunction ( 8 ). Due to an abundance of polyunsaturated
Salma R Ali
Salma R Ali
Developmental Endocrinology Research Group, Royal Hospital for Children, University of Glasgow, Glasgow, UK
Office for Rare Conditions, University of Glasgow, Glasgow, UK
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Office for Rare Conditions, University of Glasgow, Glasgow, UK
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Melissa Gardner
Melissa Gardner
Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA
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Yiqiao Xin
Yiqiao Xin
Health Economics and Health Technology Assessment, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
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Stuart O’Toole
Stuart O’Toole
Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK
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Martyn Flett
Martyn Flett
Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK
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Boma Lee
Boma Lee
Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK
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Mairi Steven
Mairi Steven
Department of Paediatric Surgery, Royal Hospital for Children, Glasgow, UK
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David E Sandberg
David E Sandberg
Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA
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S Faisal Ahmed
S Faisal Ahmed
Developmental Endocrinology Research Group, Royal Hospital for Children, University of Glasgow, Glasgow, UK
Office for Rare Conditions, University of Glasgow, Glasgow, UK
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Office for Rare Conditions, University of Glasgow, Glasgow, UK
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associated with adverse psychosocial and psychosexual outcomes ( 2 , 3 , 4 , 5 , 6 ). Studies have shown that a subset of parents of children with such conditions can experience high levels of depression, anxiety, and stress related to concerns regarding
Laura Chioma
Laura Chioma
Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
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Carla Bizzarri
Carla Bizzarri
Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
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Martina Verzani
Martina Verzani
Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
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Daniela Fava
Daniela Fava
Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Mariacarolina Salerno
Mariacarolina Salerno
Paediatric Endocrinology Unit, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
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Donatella Capalbo
Donatella Capalbo
Paediatric Endocrinology Unit, Department of Mother and Child, University Hospital Federico II, Naples, Italy
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Chiara Guzzetti
Chiara Guzzetti
Paediatric Endocrine Unit, Paediatric Hospital Microcitemico ‘A. Cao’, AO Brotzu, Cagliari, Italy
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Laura Penta
Laura Penta
Pediatric Clinic, Department of Medicine and Surgery, University of Perugia, Perugia, Italy
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Luigi Di Luigi
Luigi Di Luigi
Endocrinology Unit, Department of Movement, Human and Health Sciences, University of Rome ‘Foro Italico’, Rome, Italy
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Natascia di Iorgi
Natascia di Iorgi
Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Mohamad Maghnie
Mohamad Maghnie
Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Sandro Loche
Sandro Loche
Paediatric Endocrine Unit, Paediatric Hospital Microcitemico ‘A. Cao’, AO Brotzu, Cagliari, Italy
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Marco Cappa
Marco Cappa
Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
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during lockdown, while daily physical activity decreased with a concomitant increase of sedentary behavior ( 20 ). Finally, an increase of stress-related symptoms has been observed in children and adolescents throughout the pandemic ( 21 , 22 ). This
Maria Angela D'amico
Maria Angela D'amico
Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy
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Barbara Ghinassi
Barbara Ghinassi
Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy
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Pascal Izzicupo
Pascal Izzicupo
Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy
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Lamberto Manzoli
Lamberto Manzoli
Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy
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A Di Baldassarre
A Di Baldassarre
Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy
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protective effect against oxidative stress. Serpinin's influence on cardiac activity has recently been reported (7) . Figure 1 (A) Scheme of exonic regions of CgA and derived peptides. The human CgA gene is organized in eight exons and seven introns. The
Xuhua Mao
Xuhua Mao
Department of Clinical Laboratory, Yixing People’s Hospital, Yixing, Wuxi, Jiangsu, China
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Hucheng Chen
Hucheng Chen
Department of Nuclear Medicine, Nanjing Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu, China
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Junmin Tang
Junmin Tang
Department of Clinical Laboratory, Yixing People’s Hospital, Yixing, Wuxi, Jiangsu, China
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Liangliang Wang
Liangliang Wang
Department of Neurology, Yixing People’s Hospital Affiliated to Jiangsu University, Yixing, Wuxi, Jiangsu, China
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Tingting Shu
Tingting Shu
Department of Central Laboratory, Jiangsu Province Official Hospital, Nanjing, Jiangsu, China
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). The restricted expression of Pdx-1 induced by gluco-toxicity decreases its DNA-binding activity to insulin promoters ( 6 , 7 , 8 ). The oxidative stress signaling pathway is thought to play an important role in the mechanism by which gluco
Jelena Stankovic
Jelena Stankovic
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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Kurt Kristensen
Kurt Kristensen
Steno Diabetes Center Aarhus (SDCA), Aarhus University Hospital, Aarhus, Denmark
Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark
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Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark
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Niels Birkebæk
Niels Birkebæk
Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark
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Jens Otto Lunde Jørgensen
Jens Otto Lunde Jørgensen
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
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Esben Søndergaard
Esben Søndergaard
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus (SDCA), Aarhus University Hospital, Aarhus, Denmark
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Steno Diabetes Center Aarhus (SDCA), Aarhus University Hospital, Aarhus, Denmark
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parallel with AVP to osmotic, hemodynamic, and unspecific stress-related stimuli such as nausea ( 5 ). In contrast to AVP, copeptin is easy to assay and measurement of copeptin has been recommended for the differential diagnosis of PPS ( 1 ). Arginine
Britt J van Keulen
Britt J van Keulen
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Michelle Romijn
Michelle Romijn
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Bibian van der Voorn
Bibian van der Voorn
Department of Pediatric Endocrinology, Sophia Kinderziekenhuis, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Marita de Waard
Marita de Waard
Emma Children’s Hospital, Amsterdam University Medical Centers, locations AMC and VUmc, Amsterdam, The Netherlands
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Michaela F Hartmann
Michaela F Hartmann
Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University, Giessen, Germany
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Johannes B van Goudoever
Johannes B van Goudoever
Emma Children’s Hospital, Amsterdam University Medical Centers, locations AMC and VUmc, Amsterdam, The Netherlands
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Stefan A Wudy
Stefan A Wudy
Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University, Giessen, Germany
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Joost Rotteveel
Joost Rotteveel
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
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Martijn J J Finken
Martijn J J Finken
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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essential for blood pressure maintenance ( 7 ) and has been presumed to play a role in the dampening of the immune response ( 8 ). During their first weeks of life, many preterm infants fail to mount an adequate cortisol response for the degree of stress or
