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M L M Barreto-Chaves, N Senger, M R Fevereiro, A C Parletta and A P C Takano

process, in order to identify possible novel therapeutic targets, is clear. In this context, this review will describe the basic aspects of TH action, focusing on the molecular and cellular mechanisms associated with cardiac hypertrophy, and the

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Adriano N Cury, Verônica T Meira, Osmar Monte, Marília Marone, Nilza M Scalissi, Cristiane Kochi, Luís E P Calliari and Carlos A Longui

a fixed dose for all patients, aiming to induce remission of the disease and achieve hypothyroidism or euthyroidism (12) . Patients and methods We reviewed the medical records of 65 patients who were followed between 1985 and 2005 with

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E T Aristizabal Prada and C J Auernhammer

. This review is focused on novel putative targeted therapies for well-differentiated NETs with G1/G2 grading of the GEP system ( 19 , 20 ). We review current preclinical and early clinical data on several putative novel targets and future challenges for

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Legh Wilkinson, Nicolette J D Verhoog and Ann Louw

development of further GC insensitivity. This review begins by briefly describing the types of GC resistance and then discusses reductions in the GRα pool in various pathological and psychological conditions, in terms of acquired GC resistance. Primary focus

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Xi Wang and Qi Yu

Hospital as part of a long-standing MAS natural history study. The study was approved by the Institutional Review Board of Peking Union Medical College Hospital (Number S-K445). Informed consent was obtained in accordance with the institutional guidelines

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Madalena von Hafe, João Sergio Neves, Catarina Vale, Marta Borges-Canha and Adelino Leite-Moreira

, an understanding of the role of THs in the cardiovascular system is imperative ( 1 ). The main goal of this manuscript is to review the central pathophysiological and clinical links between altered thyroid function and cardiovascular diseases

Open access

Giovanni Tulipano

( 12 ). The purpose of this review is to provide an overview of our current knowledge on the role played by AMPK in the regulation of neuroendocrine axes activity as a downstream mediator of metabolic signals, hormones and drugs affecting pituitary

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Majunath R Goroshi, Swati S Jadhav, Anurag R Lila, Rajeev Kasaliwal, Shruti Khare, Chaitanya G Yerawar, Priya Hira, Uday Phadke, Hina Shah, Vikram R Lele, Gaurav Malhotra, Tushar Bandgar and Nalini S Shah

reviewed retrospectively. Twelve patients diagnosed as EAS were included in the study (none of these patients had been a part of our previously published cohort) ( 17 ). The diagnosis of EAS was established after a stepwise evaluation as described

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Magaly Zappa, Olivia Hentic, Marie-Pierre Vullierme, Matthieu Lagadec, Maxime Ronot, Philippe Ruszniewski and Valérie Vilgrain

used imaging modality in oncology. Patients and methods Patient selection This was a retrospective study and a waiver was obtained from the institutional review board. From 2013 to 2014, all patients referred to our institution with a

Open access

Dirk Weismann, Andreas Schneider and Charlotte Höybye

published for the guidance on HN. The aim of the present review was to summarize the management of patients with HN in relation to everyday clinical practice with focus on the acute management. Pathophysiology HN, defined as a sNA <135 mmol/L, is