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programming’ and they can cause epigenetic changes ( 10 ). Epigenetic changes ascribe to the change in the biochemical structure of DNA that ultimately alters gene expression. This includes DNA methylation, histone modification and non-coding RNA processes
Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
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maturation, and short stature . Pediatric Research 2020 88 117 – 124 . ( https://doi.org/10.1038/s41390-019-0690-3 ) 36 Romens SE McDonald J Svaren J Pollak SD Associations between early life stress and gene methylation in children . Child
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using the Holm criteria ( 4 ) combined with newly established methylation testing techniques for 15 q analysis ( 16 ). Until 2011, clinical, biochemical, pelvic ultrasound and surgical treatment details on PWS patients were collected on a rolling basis
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by altering gene methylation, by changing the configuration of histone cores around which chromatid chains are wound within the chromosomes, or by inducing changes in non-coding genetic RNA ( 34 ). Many mechanistic effects improve function or
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
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Saint Vincent’s Clinical School, UNSW Sydney, Sydney, Australia
SydPath, Saint Vincent’s Hospital, Sydney, Australia
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Gene & Stem Cell Therapy Program Centenary Institute, The University of Sydney, Camperdown, New South Wales, Australia
Faculty of Medicine & Health, The University of Sydney, Camperdown, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
School of Medicine, University of Wollongong, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Department of Head & Neck Surgery, Liverpool Hospital, Liverpool, New South Wales, Australia
Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
South West Sydney Clinical School, UNSW Sydney, Sydney, Australia
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expression is regulated by both DNA methylation and NF-kB during EMT signaling in non-small cell lung carcinoma . Oncoimmunology 2018 7 e1423170. ( https://doi.org/10.1080/2162402X.2017.1423170 ) 41 Funaki S Shintani Y Fukui E Yamamoto Y
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, which could improve diagnosis and treatment of PCOS patients. Polymorphic variants of genes have been garnered mainly by genome-wide analysis and epigenetic regulation such as DNA methylation and noncoding RNAs have been more recently linked with PCOS
Diagnósticos da América SA, Rio de Janeiro, Rio de Janeiro, Brazil
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Neuroendocrinology Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil
Endocrinology Unit, Hospital Federal de Bonsucesso, Rio de Janeiro, Rio de Janeiro, Brazil
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National Cancer Institute, Rio de Janeiro, Rio de Janeiro, Brazil
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Molecular Genetics Laboratory, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil
Neuroendocrinology Unit, Instituto Estadual do Cérebro Paulo Niemeyer, Rio de Janeiro, Rio de Janeiro, Brazil
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development of the pituitary tumor, such as downregulation of gene expression through promoter methylation ( 37 ) or via microRNAs ( 38 ). One of our important findings is that we have not identified somatic mutations in the tumor samples studied. This is in
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heterogeneity statistically demonstrated along with the effects. MI is the most abundant form of inositol in humans. It can turn into various derivatives through either epimerization, phosphorylation or methylation of its hydroxyl groups. The NAD
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EHESP-School of Public Health, Rennes, France
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Inserm (Institut National de la Santé et de la Recherche Médicale), Irset – Inserm, UMR 1085, Rennes, France
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–child pairs . Human Reproduction 2017 32 223 – 231 . ( https://doi.org/10.1093/humrep/dew285 ) 39 Labosky P Barlow D Hogan B. Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of
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Inawaka K Kawabe M Takahashi S Doi Y Tomigahara Y Tarui H Abe J Kawamura S Shirai T. Maternal exposure to anti-androgenic compounds, vinclozolin, flutamide and procymidone, has no effects on spermatogenesis and DNA methylation in male