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R Perchard, L Magee, A Whatmore, F Ivison, P Murray, A Stevens, M Z Mughal, S Ehtisham, J Campbell, S Ainsworth, M Marshall, M Bone, I Doughty and P E Clayton

seasonality was eliminated with a vitamin D-fortified diet ( 16 ). In a systematic review and meta-analysis conducted by Zipitis and coworkers ( 17 ), the risk of T1D was significantly reduced in individuals who had received cholecalciferol in early infancy

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M A Webb, H Mani, S J Robertson, H L Waller, D R Webb, C L Edwardson, D H Bodicoat, T Yates, K Khunti and M J Davies

that PA reduces expression of CD14+ and CD16 positive monocytes cells which are potent producers of inflammatory cytokines ( 29 ). Whilst a plethora of reports have shown an increased risk of CVD and T2DM with PCOS, meta-analysis has not detected an

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Enrique Soto-Pedre, Paul J Newey, John S Bevan and Graham P Leese

of overall cancer or breast cancer. The prospective Nurses’ Health Study (NHS and NHSII) and a meta-analysis of 7 observational studies reported an increased risk of breast cancer of borderline significance, with the latter showing a relative risk of

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Xiao-jun Zhou, Lin Ding, Jia-xin Liu, Le-qun Su, Jian-jun Dong and Lin Liao

between Asians and non-Asians: a systematic review and meta-analysis . Diabetologia 2013 56 696 – 708 . ( ) 23344728 10.1007/s00125-012-2827-3 12 Sjostrand M Wei C Cook W Johnsson K Pollack PS Stahre C

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Xiujuan Su, Yan Zhao, Zhijuan Cao, Yingying Yang, Tony Duan and Jing Hua

hypothyroxinaemia, but this observation was imprecise due to sparse data (two cases in the IMH group). A meta-analysis that included 15 studies showed that IMH had no association with preterm delivery, which agrees with our study ( 29 ). No association was

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N Bergmann, F Gyntelberg and J Faber

Introduction The metabolic syndrome (MES) is a cluster of risk factors including male adiposity, dyslipidemia, reduced glucose tolerance and hypertension. MES is highly prevalent and increasing in most parts of the world (1) . A meta-analysis has

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Alessandro Brancatella and Claudio Marcocci

cells. Numerous studies have proven the utility of TSH suppressive therapy in patients with DTC. A meta-analysis of 10 studies from the 1970s to the 1990s showed that TSH suppressive therapy was useful in decreasing mortality and morbidity associated

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Martine Cohen-Solal, Thomas Funck-Brentano and Pablo Ureña Torres

absence of CKD. In a meta-analysis of 13 studies ( 25 ), only one study mentioned the presence of vertebral fracture in relation to dialysis, finding no association between risk of fracture and BMD. The 2017 KDIGO (Kidney Dialysis Improving Global Outcomes

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Changjiao Yan, Meiling Huang, Xin Li, Ting Wang and Rui Ling

rate of 38.3% in patients between 1990 and 2012 ( 15 ). In 2007, Electron et al . reported the prevalence of BRAF V600E was 46.4% ( 16 ). In 2012, Kurtulmus et al . showed BRAF V600E mutation rate of 39.45% in PTCs ( 17 ). The meta-analysis showed

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Christian Trummer, Stefan Pilz, Verena Schwetz, Barbara Obermayer-Pietsch and Elisabeth Lerchbaum

no treatment effect on pregnancy outcomes, the endometrial thickness was significantly higher in the vitamin D when compared to the placebo group. Meta-analyses A recent meta-analysis ( 63 ) including 16 studies involving 315 participants on