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G Amiyangoda Department of Pharmacology, Faculty of Medicine, University of Peradeniya, Sri Lanka
Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka

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C N Antonypillai Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka

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S S C Gunatilake Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka

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T T Weerathunge Department of Community Medicine, Faculty of Medicine, University of Colombo, Sri Lanka

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D Ediriweera Health Data Science Unit, Faculty of Medicine, University of Kelaniya, Sri Lanka

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S G P D Kosgallana Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka

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R D P Jayawardana Department of Biochemistry, National Hospital, Kandy, Sri Lanka

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H A N D Thissera Department of Biochemistry, National Hospital, Kandy, Sri Lanka

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W J Emalka Faculty of medicine, University of Peradeniya, Sri Lanka

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H U Daraniyagala Faculty of medicine, University of Peradeniya, Sri Lanka

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). Free triiodothyronine (FT3) binds to the nuclear receptors in the cells to exert its biological action. Refractory hypothyroidism is defined as the requirement of higher doses of levothyroxine, typically 1.9–2.5 μg/kg/day, to maintain biochemical and

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Hana Vítková Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic

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Kateřina Anderlová Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic
Department of Gynaecology, Obstetrics and Neonatology, First Faculty of Medicine Charles University and General University Hospital in Prague, Prague, Czech Republic

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Jan Krátký Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic

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Radovan Bílek Institute of Endocrinology, Prague, Czech Republic

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Drahomíra Springer Institute of Clinical Biochemistry and Laboratory Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic

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Felix Votava Department of Children and Adolescents, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic

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Tomáš Brutvan Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic

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Adéla Krausová Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic

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Kristýna Žabková Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic

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Eliška Potluková University Center of Internal Medicine, Cantonal Hospital Baselland and University of Basel, Switzerland

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Jan Jiskra Third Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic

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’s HbA1c ( N =79) – – NS NS 58.072 (22.22) P  = 0.02 NS NS NS Data are expressed as a coefficient (standard error). crf, circumference; FT4, free thyroxine (pmol/L), FT3, free triiodothyronine (pmol/L); GDM, gestational

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Madalena von Hafe Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal

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João Sergio Neves Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal

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Catarina Vale Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal

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Marta Borges-Canha Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal
Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal

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Adelino Leite-Moreira Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal

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. ( https://doi.org/10.1155/2014/481482 ) 24683435 91 Jankauskiene E Orda P Barauskiene G Mickuviene N Brozaitiene J Vaskelyte JJ Bunevicius R . Relationship between left ventricular mechanics and low free triiodothyronine levels after myocardial

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Flavia Letícia Martins Peçanha Instituto de Bioquímica Médica Leopoldo de Meis, Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, Rio de Janeiro, Brazil

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Reinaldo Sousa dos Santos Instituto de Bioquímica Médica Leopoldo de Meis, Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, Rio de Janeiro, Brazil

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Wagner Seixas da-Silva Instituto de Bioquímica Médica Leopoldo de Meis, Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, Rio de Janeiro, Brazil

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triiodothyronine (total T 3 ) antibody coated tube ( 125 I RIA kit); and a free triiodothyronine (free T 3 ) antibody coated tube ( 125 I RIA kit) (MP Biomedicals, Santa Ana, CA, USA), following the manufacturer’s instructions. Cell culture The C2C12

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M Krause Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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H Frederiksen Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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K Sundberg Center of Fetal Medicine and Pregnancy, Department of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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F S Jørgensen Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark

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L N Jensen Center of Fetal Medicine and Pregnancy, Department of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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P Nørgaard Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark

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C Jørgensen Center of Fetal Medicine and Pregnancy, Department of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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P Ertberg Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark

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J H Petersen Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Section of Biostatistics, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark

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U Feldt-Rasmussen Department of Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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A Juul Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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K T Drzewiecki Department of Plastic Surgery, Breast Surgery and Burns Treatment, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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N E Skakkebaek Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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A M Andersson Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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exception of two samples, which were analyzed for thyroid hormones in March 2017. The thyroid hormones triiodothyronine (T 3 ), free triiodothyronine (fT 3 ), thyroxine (T 4 ) and free thyroxine (fT 4 ) were measured by competitive electrochemiluminescence

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Maria Stelmachowska-Banaś Department of Endocrinology, The Centre of Postgraduate Medical Education, Warsaw, Polska, Poland

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Izabella Czajka-Oraniec Department of Endocrinology, The Centre of Postgraduate Medical Education, Warsaw, Polska, Poland

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-stimulating hormone; fT3, free triiodothyronine; fT4, free thyroxine; GCSs, glucocorticoids; HbA1c, hemoglobin A1c; K, potassium; LH, luteinizing hormone; MRI, magnetic resonance imaging; Na, sodium; P, phosphorus; PTH, parathyroid hormone; SST, short Synacthen test

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