Sahar Hossam El Hini
Sahar Hossam El Hini
Diabetes and Endocrinology Unit, Department of Internal Medicine, Faculty of Medicine, Minia University, Minia, Egypt
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Yehia Zakaria Mahmoud
Yehia Zakaria Mahmoud
Department of Internal Medicine, Faculty of Medicine, Minia University, Minia, Egypt
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Ahmed Abdelfadel Saedii
Ahmed Abdelfadel Saedii
Department of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt
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Sayed Shehata Mahmoud
Sayed Shehata Mahmoud
Department of Cardiology, Faculty of Medicine, Minia University, Minia, Egypt
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Mohamed Ahmed Amin
Mohamed Ahmed Amin
Department of Radiology, Faculty of Medicine, Minia University, Minia, Egypt
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Shereen Riad Mahmoud
Shereen Riad Mahmoud
Diabetes and Endocrinology Unit, Department of Internal Medicine, Faculty of Medicine, Minia University, Minia, Egypt
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Ragaa Abdelshaheed Matta
Ragaa Abdelshaheed Matta
Diabetes and Endocrinology Unit, Department of Internal Medicine, Faculty of Medicine, Minia University, Minia, Egypt
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fasting plasma glucose (FPG), complete lipogram (total cholesterol and HDL-c, triglycerides, and calculated LDL-c) using standard laboratory methods. THs (TSH, freeT3 (FT3), and FT4) were assessed using Mini Vidas via enzyme-linked fluorescence immunoassay
Shi-en Fu
Shi-en Fu
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Rou-mei Wang
Rou-mei Wang
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Xing-huan Liang
Xing-huan Liang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jing Xian
Jing Xian
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jie Pan
Jie Pan
Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Xue-lan Chen
Xue-lan Chen
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Cheng-cheng Qiu
Cheng-cheng Qiu
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Zhi-ping Tang
Zhi-ping Tang
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Ying-fen Qin
Ying-fen Qin
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Hai-yan Yang
Hai-yan Yang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Li-li Huang
Li-li Huang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
Department of Endocrinology, The Affiliated Hospital of Guilin Medical University, Guilin, China
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Department of Endocrinology, The Affiliated Hospital of Guilin Medical University, Guilin, China
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Ya-qi Kuang
Ya-qi Kuang
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Yan Ma
Yan Ma
Department of Ultrasonic Diagnosis, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Zuo-jie Luo
Zuo-jie Luo
Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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min at 956 g . Serum thyroid hormone concentrations were assessed using the chemiluminescent immunoassay (TEGEN, TESMI i-200, Shanghai, China). For this assay, the limit of detection for free triiodothyronine (FT3) was 3.6–6.0 pmol/L, free
Yun Hu
Yun Hu
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
Department of Immunology, Nanjing Medical University, Jiangsu, China
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Department of Immunology, Nanjing Medical University, Jiangsu, China
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Na Li
Na Li
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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Peng Jiang
Peng Jiang
Department of Thyroid and Breast Surgery, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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Liang Cheng
Liang Cheng
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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Bo Ding
Bo Ding
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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Xiao-Mei Liu
Xiao-Mei Liu
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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Ke He
Ke He
Department of Endocrinology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Jiangsu, China
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Yun-Qing Zhu
Yun-Qing Zhu
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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Bing-li Liu
Bing-li Liu
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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Xin Cao
Xin Cao
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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Hong Zhou
Hong Zhou
Department of Immunology, Nanjing Medical University, Jiangsu, China
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Xiao-Ming Mao
Xiao-Ming Mao
Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
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time. Linear regression analysis showed that Tg level was negatively correlated with the inhibitory function of Tregs in the peripheral blood ( R = −0.398, P = 0.03, Fig. 1A ). This association remained significant when gender; age; TSH, FT3, FT4
Ya-Fen Hu
Ya-Fen Hu
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
Department of Endocrinology, The People’s Hospital of Daxing District, Beijing, China
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Department of Endocrinology, The People’s Hospital of Daxing District, Beijing, China
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Lin Hua
Lin Hua
Department of Mathematics, School of Biomedical Engineering, Capital Medical University, Beijing, China
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Xiu Tuo
Xiu Tuo
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Ting-Ting Shi
Ting-Ting Shi
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Yi-Lin Yang
Yi-Lin Yang
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Yun-Fu Liu
Yun-Fu Liu
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Zhong-Yu Yan
Zhong-Yu Yan
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Zhong Xin
Zhong Xin
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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blood was collected from the subjects after an overnight fast. The levels of serum T3, T4, FT3, FT4, and thyroid stimulating hormone (TSH) were assayed using ADVIA Centaur XP Immunoassay System (Siemens Diagnostics) and that of thyroperoxidase antibody
Yue-Yue Wang
Yue-Yue Wang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Qian Wu
Qian Wu
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Lu Chen
Lu Chen
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Wen Chen
Wen Chen
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Tao Yang
Tao Yang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Xiao-Quan Xu
Xiao-Quan Xu
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Fei-Yun Wu
Fei-Yun Wu
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Hao Hu
Hao Hu
Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Huan-Huan Chen
Huan-Huan Chen
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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.637 Sex (F/M) 15/8 8/6 0.732 Smoking history 6/17 5/9 0.713 Disease duration (months) 4.2 ± 2.6 (1–12) 8.6 ± 5.5 (4–17) 0.003 a CAS 4.0 ± 0.8 (3–6) 3.9 ± 0.8 (3–5) 0.840 FT3 (pmol/L) 5.86 ± 2.76 (3
Luca Persani
Luca Persani
Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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Biagio Cangiano
Biagio Cangiano
Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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Marco Bonomi
Marco Bonomi
Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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in adults ( 1 , 36 ). Therefore, the FT4 determination, more than the TT4, which is influenced by the serum-binding protein variation ( 37 , 38 ) or the FT3, which might be low in some nonthyroidal illness or deiodinase defect rather than in CeH
Xingyao Tang
Xingyao Tang
Beijing Tongren Hospital, Capital Medical University
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Zhi-Hui Song
Zhi-Hui Song
Department of Pharmacy, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Dawei Wang
Dawei Wang
General Practice Department, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Jinkui Yang
Jinkui Yang
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Marly Augusto Cardoso
Marly Augusto Cardoso
Department of Nutrition, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil
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Jian-Bo Zhou
Jian-Bo Zhou
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Rafael Simó
Rafael Simó
Endocrinology and Nutrition Department, Hospital Universitari Vall d’Hebron, Diabetes and Metabolism Research Unit, Vall d’Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain
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Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain
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.2 nmol/L 0.3–4.0 Every 6 months of decreased TSH was associated with an increased risk of dementia by 16%, compared to individuals with normal TSH. 9 FT3, free triiodothyronine; FT4, free thyroxine; NOS, score of Newcastle–Ottawa Scale
Christin Krause
Christin Krause
Epigenetics & Metabolism, Medical Department I, University of Lübeck, Lübeck, Germany
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Martina Grohs
Martina Grohs
Epigenetics & Metabolism, Medical Department I, University of Lübeck, Lübeck, Germany
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Alexander T El Gammal
Alexander T El Gammal
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Stefan Wolter
Stefan Wolter
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Hendrik Lehnert
Hendrik Lehnert
Medical Department I, University of Lübeck, Lübeck, Germany
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Oliver Mann
Oliver Mann
Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Jens Mittag
Jens Mittag
Molecular Endocrinology, Medical Department I, University of Lübeck, Lübeck, Germany
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Henriette Kirchner
Henriette Kirchner
Epigenetics & Metabolism, Medical Department I, University of Lübeck, Lübeck, Germany
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,3′,5-triiodothyronine (fT3) and lower free thyroxine (fT4) levels has been described ( 7 ); however, the negative correlations of NAFLD with fT3 and fT4 in these euthyroid subjects suggest that the local hepatic levels of TH might be of even greater relevance for the
Qing Zhou
Qing Zhou
Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China
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Li Yong Zhang
Li Yong Zhang
Department of Thyroid Surgery, Minimal Invasive Center, Fujian Medical University Union Hospital, Fuzhou, China
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Mei Feng Dai
Mei Feng Dai
Department of Clinical Lab, Fujian Maternity and Child Health Hospital, Fuzhou, China
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Zhen Li
Zhen Li
Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China
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Chao Chun Zou
Chao Chun Zou
Department of Endocrinology, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China
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Hui Liu
Hui Liu
Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China
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, and TNF-α and interleukin-6 (IL-6) concentrations were measured using an ELISA kit (R&D Systems) according to the manufacturer’s instructions. For the in vivo experiment, serum TSH, FT3, and FT4 levels of mice were determined using an ELISA kit
Eng-Loon Tng
Eng-Loon Tng
Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore
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Yee Sian Tiong
Yee Sian Tiong
Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore
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Aye Thida Aung
Aye Thida Aung
Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore
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Nicole Ya Yuan Chong
Nicole Ya Yuan Chong
Department of Medicine, National University Hospital, Singapore
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Zhemin Wang
Zhemin Wang
Department of Medicine, National University Hospital, Singapore
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study in Hong Kong. Follow-up duration = 47 months (median) (IQR: 24 – 82).Hyperthyroidism was defined as elevated FT4 or FT3 and concomitant suppressed TSH. AF or atrial flutter was confirmed with standard 12-lead ECG. One hundred thirty
