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, 8 ), as well as thyroid hormones ( 9 ) in the human vocal fold. Furthermore, a few research papers hypothesize the voice changes in diabetes mellitus (DM) due to its microvascular complications. The multifaceted mechanism of possible voice changes
Department of Anatomy, Shanxi Medical University, Taiyuan, China
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Introduction Diabetes mellitus (DM) is a progressive and chronic metabolic disease with multiple etiologies. DM is characterized by defective glucose metabolism due to low levels or an absolute lack of insulin, which seriously threatens human
Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, People’s Republic of China
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Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, People’s Republic of China
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Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, People’s Republic of China
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Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan, People’s Republic of China
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osseointegration, which is critical for implanting, and increase the failure rate, type 2 diabetes mellitus (T2DM) is one of them ( 1 , 2 ). The pathological changes of T2DM, such as microangiopathy, immunity decline and collagen degradation, can reduce the
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-2) and 20 type 2 diabetes mellitus patients (group 3) who were made a diagnosis with breast cancer and applied to the Cumhuriyet University Medicine Faculty Oncology Policlinic were included in the study. It was not made restriction respect to the
Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Unit of Endocrinology, Diabetes Mellitus and Metabolism, ARETAIEION University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Introduction
To investigate whether synthetic (s) glucocorticoids (GCs) administered between the 24th and the 34th gestational weeks in pre-term labor might precipitate labor, studies on sGCs administration were reviewed. The physiology of endogenous glucocorticoid-related increase in fetal–maternal circulation and its association with labor, followed by a scoping review of studies on exogenous sGCs administered for fetal lung maturation and the timing of labor, were included.
Materials and methods
The methodology of systematic reviews was followed. MEDLINE, Cochrane Library, and Google Scholar databases were searched until October 2023, for original studies investigating the administration of sGCs in pregnancies risking pre-term labor. Duplicates were removed, and 1867 abstracts were excluded as irrelevant. Six controlled and four non-controlled studies were included. The index group consisted of 6001 subjects and 7691 controls in the former, while in the latter, the index group consisted of 2069 subjects.
Results
In three out of the six controlled studies, gestational age at labor was significantly lower in sGC-treated women than in controls, while in three studies, gestational age at labor was lower in sGC-treated women than in controls, with a trend toward statistical significance. In one study, gestational age at labor was significantly lower in controls than in sGC-treated women. In the non-controlled studies, the majority of women delivered less than 1 week from the day of sGC administration.
Conclusions
In this scoping review, studies lack homogeneity. However, in the controlled studies, a pattern of earlier labor emerges among sGC-treated pregnant women. The use of multiple courses of antenatal sGCs appears to be associated with precipitated labor. Their use should be carefully weighed. Carefully designed trials should examine this ongoing scientific query.
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prediabetes and new-onset diabetes. As a basic characteristic of type 2 diabetes mellitus (T2DM), insulin resistance plays an important role in the development and progression of arteriosclerosis. Insulin resistance is present in prediabetes, and populations
Chronic Disease Epidemiology Laboratory Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
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Introduction The worldwide rise in over-nutrition, sedentary life and obesity has resulted in a steep increase in the number of women who develop gestational diabetes mellitus (GDM) during pregnancy ( 1 ). Nearly 7% of pregnancies in the
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Introduction Gestational diabetes mellitus (GDM) is a condition of glucose intolerance usually occurring during the late stage of pregnancy due to decreased maternal insulin sensitivity and increased glucose production, and often recovers
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21 . ( https://doi.org/10.1016/j.cell.2016.10.043 ) 5 Hasain Z Mokhtar NM Kamaruddin NA Mohamed Ismail NA Razalli NH Gnanou JV Raja Ali RA Gut microbiota and gestational diabetes mellitus: a review of host-gut microbiota interactions
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Introduction According to recent statistics, 529 million people will have diabetes worldwide in 2021, and the global age-standardized total diabetes prevalence will be 6.1% ( 1 ). Type 2 diabetes mellitus (T2DM) is the most frequent form of
