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Line K Johnson Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Kirsten B Holven Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Njord Nordstrand Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Jan R Mellembakken Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Tom Tanbo Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Jøran Hjelmesæth Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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was recommended (Collett Kostpluss, Axellus Oslo, Oslo, Norway). Additionally, participants could eat an unlimited amount of vegetables and one fruit per day. Estimated macronutrient intakes from fat, protein, total carbohydrate and fructose are shown

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0047
Volume/Issue:
Volume 4: Issue 3
Open access
Myrian Velasco Neuroscience Division, Department of Cognitive Neuroscience, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico

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Rosa Isela Ortiz-Huidobro Neuroscience Division, Department of Cognitive Neuroscience, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico

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Carlos Larqué Department of Embryology and Genetics, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

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Yuriko Itzel Sánchez-Zamora Neuroscience Division, Department of Cognitive Neuroscience, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico

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José Romo-Yáñez Department of Gynecological and Perinatal Endocrinology, Instituto Nacional de Perinatología ‘Isidro Espinosa de los Reyes’, Mexico City, Mexico

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Marcia Hiriart Neuroscience Division, Department of Cognitive Neuroscience, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico

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cycle, at 20–23°C and 40% of relative humidity. All animals were fed with standard rat chow (Lab Diet 5001) composed by 28.5% protein, 13.5% fat, and 58% carbohydrates. Tap water or 20% (w/v) sucrose solution was provided to the control group or to the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0288
Volume/Issue:
Volume 9: Issue 9
Open access
Jessica S Jarmasz Department of Physiology & Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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Yan Jin Department of Physiology & Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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Hana Vakili Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

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Peter A Cattini Department of Physiology & Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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libitum. Male 3–4 week old 171hGH/CS TG CD-1 mice were used since growth hormone levels are at their highest during puberty (onset at days 21–35) ( 28 ). Mice were randomly assigned to receive RCD (fat 14 kcal%, carbohydrate 60 kcal%, and protein 25 kcal

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0354
Volume/Issue:
Volume 9: Issue 12
Open access
Nannan Bian Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Xiaomeng Sun Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Biao Zhou Departments of General Surgery and Obesity and Metabolic Disease Center, China-Japan Friendship Hospital, Beijing, China

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Lin Zhang Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Qiu Wang Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Yu An Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Xiaohui Li Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Yinhui Li Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Jia Liu Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Hua Meng Departments of General Surgery and Obesity and Metabolic Disease Center, China-Japan Friendship Hospital, Beijing, China

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Guang Wang Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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the diet (carbohydrate vs lipids), but we did not control for the ratio of carbohydrate to lipid intake. Fourthly, we found that the elevated TSH may be beneficial to the improvement of FBG, FINS, adipo-IR and TSH after bariatric surgery in non

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0360
Volume/Issue:
Volume 10: Issue 10
Open access
Marie Oertel Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany

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Christian G Ziegler Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany
Department of Internal Medicine III, University Hospital Carl Gustav Carus Dresden, Dresden, Germany

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Michael Kohlhaas Comprehensive Heart Failure Center, Würzburg, Germany

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Alexander Nickel Comprehensive Heart Failure Center, Würzburg, Germany

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Simon Kloock Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany

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Christoph Maack Comprehensive Heart Failure Center, Würzburg, Germany

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Vasco Sequeira Comprehensive Heart Failure Center, Würzburg, Germany

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Martin Fassnacht Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany

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Ulrich Dischinger Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany
Comprehensive Heart Failure Center, Würzburg, Germany

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temperature of 22°C and a 12-h light/12-h darkness cycle. To induce obesity, the animals had free access to a HFD (D12451 HF diet from Ssniff, Germany, 4615 kcal/kg; 45 kJ% fat, 20 kJ% protein, 35 kJ% carbohydrates) for 8 weeks. Thereafter, animals (mean body

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0398
Volume/Issue:
Volume 13: Issue 3
Open access
Michael C Velarde Institute of Biology, College of Science, University of the Philippines Diliman, Quezon, Metro Manila, Philippines

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Mikaela Erlinda M Bucu Department of Obstetrics and Gynecology, College of Medicine, University of the Philippines Manila, Metro Manila, Philippines

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Maria Antonia E Habana Department of Obstetrics and Gynecology, College of Medicine, University of the Philippines Manila, Metro Manila, Philippines

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sources of carbohydrates and tend to eat more nuts, legumes, and fishes than other ethnicities ( 49 ). Asians also eat more vegetables and strong spices as part of their diet. Likewise, Asians in the United States have the highest intake of rice and fishes

Article Type:
Review Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-23-0169
Volume/Issue:
Volume 12: Issue 11
Open access
Maria Houborg Petersen Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark

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Jacob Volmer Stidsen Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark

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Martin Eisemann de Almeida Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark
Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark

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Emil Kleis Wentorf Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark

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Kurt Jensen Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark

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Niels Ørtenblad Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark

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Kurt Højlund Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark

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–euglycemic clamp, respectively, the Botnia clamp is a suggested alternative ( 24 , 29 ). The IVGTT has shown reproducibility ( 24 , 43 ), and has been suggested as the most precise method to determine first-phase insulin secretion in response to a carbohydrate

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0558
Volume/Issue:
Volume 13: Issue 5
Open access
R Perchard Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK

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L Magee Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK

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A Whatmore Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK

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F Ivison Department of Biochemistry, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK

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P Murray Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK
Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Central Manchester Foundation Hospitals NHS Trust, Manchester, UK

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A Stevens Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK

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M Z Mughal Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Central Manchester Foundation Hospitals NHS Trust, Manchester, UK

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S Ehtisham Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Central Manchester Foundation Hospitals NHS Trust, Manchester, UK

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J Campbell Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Central Manchester Foundation Hospitals NHS Trust, Manchester, UK

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S Ainsworth Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Central Manchester Foundation Hospitals NHS Trust, Manchester, UK

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M Marshall Department of Biochemistry, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK

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M Bone Department of General Paediatrics, Royal Manchester Children’s Hospital, Central Manchester Foundation Hospitals NHS Trust, Manchester, UK

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I Doughty Department of General Paediatrics, Royal Manchester Children’s Hospital, Central Manchester Foundation Hospitals NHS Trust, Manchester, UK

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P E Clayton Division of Developmental Biology & Medicine, School of Medical Sciences, Faculty of Biology, Medicine & Health, University of Manchester, Manchester, UK
Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Central Manchester Foundation Hospitals NHS Trust, Manchester, UK

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impact of puberty. However, total daily insulin dose was not available for 25 participants where diabetes control was centred on carbohydrate counting. This limited our analysis and the ability of our models to control for this. A further study limitation

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0045
Volume/Issue:
Volume 6: Issue 4
Open access
Esben Thyssen Vestergaard Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark

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Morten B Krag Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark

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Morten M Poulsen Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark

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Steen B Pedersen Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark

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Niels Moller Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark

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Jens Otto Lunde Jorgensen Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark

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Niels Jessen Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark

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periods were separated by a 1- to 3-week washout period. Participants were prior to the study instructed by a clinical dietician to consume a weight-stable diet containing 50–60% carbohydrates, maximum 30% fat, and protein at 10–15% of total energy intake

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-13-0019
Volume/Issue:
Volume 2: Issue 2
Open access
Ursula M M Costa Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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Carla R P Oliveira Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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Roberto Salvatori Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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José A S Barreto-Filho Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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Viviane C Campos Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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Francielle T Oliveira Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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Ivina E S Rocha Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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Joselina L M Oliveira Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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Wersley A Silva Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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Manuel H Aguiar-Oliveira Division of Cardiology, Division of Endocrinology, Division of Endocrinology, Federal University of Sergipe, Aracaju, SE 49060-100, Brazil

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. Both GHD and controls reside in the same area, which is becoming progressively more urbanized. While we have recently reported that GHD subjects consume in percentage more proteins, less carbohydrates and equal amount of lipids in comparison with the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0118
Volume/Issue:
Volume 5: Issue 1
Open access