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Postgraduate Program in Nutritional Sciences, Department of Nutrition, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil
University Centre of João Pessoa (UNIPE), João Pessoa, Paraíba, Brazil
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Postgraduate Program in Cognitive Neuroscience and Behavior, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil
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Department of Biorregulation, Health Sciences Institute, Federal University of Bahia, Bahia, Brazil
Postgraduate Program in Medicine and Health, Medical School of Medicine, Federal University of Bahia, Salvador, Bahia, Brazil
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associated with insulin resistance, worse metabolic health, and systemic inflammation; many authors have discussed that fat distribution itself would be a better marker of worse outcomes in COVID-19, and research helps to corroborate that hypothesis ( 26
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weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial . Gut 2019 68 83 – 93 . ( https://doi.org/10.1136/gutjnl-2017-314786 ) 9 Larsen N Vogensen FK van den Berg FW Nielsen DS
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develop type 2 diabetes mellitus 10 years after GDM ( 2 , 3 , 4 , 5 ). Women with GDM typically have different levels of insulin resistance and possible chronic low-grade inflammation, which trigger vascular injury and dysfunction and subsequent
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glucose clearance. It is responsible for the majority of glucose uptake in the postprandial state and is also considered as the primary driver of systemic insulin resistance ( 6 , 7 ). Due to its crucial role in systemic glycometabolism, skeletal muscle
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Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
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Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA
Harvard Medical School, Boston, Massachusetts, USA
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effect on sclerostin may vary with the duration of glucocorticoid therapy. For example, the initiation of glucocorticoid therapy (30–60 mg/day of prednisolone) in patients with systemic autoimmune diseases led to significant increases in serum sclerostin
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visceral adiposity, and systemic chronic inflammation. On the one hand, ER stress upregulates inflammatory gene expression and increases pro-inflammatory cytokine production. On the other hand, as a key mediator of ER stress that leads to insulin resistance
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of Laboratory Physicians 2016 8 101 – 105 . ( https://doi.org/10.4103/0974-2727.180790 ) 19 Romano M Guagnano MT Pacini G Vigneri S Falco A Marinopiccoli M Manigrasso MR Basili S Davi G . Association of inflammation markers
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bovines, and represents a general marker of neuroendocrine tumors (NETs) (5) . Exon VII encodes for the dysglycemic hormone pancreastatin (PST: hCgA 250 – 301 ), the catecholamine release-inhibitory and antihypertensive peptide catestatin, a 20 amino acid
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Wellcome–MRC Institute of Metabolic Science, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK
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inhibition. The uninhibited AngII may then play a role in the pathogenesis of observed hypertension ( 6 ), inflammation, immunothrombosis and possible fibrosis in COVID-19. Whilst elevated serum cortisol has been identified as a marker of poor prognosis in
Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
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Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
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Department of Ophthalmology, Skåne University Hospital, Malmö, Sweden
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Department of Diabetes & Endocrinology, Skåne University Hospital, Malmö, Sweden
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inflammation both by recruiting mononuclear cells to the site of inflammation and by systemically elevating the numbers of B- and T-lymphocyte populations; these results explain the severe state of GO in smokers and may in part explain the association of