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Xiaoxia Jia Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yaxin An Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yuechao Xu Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yuxian Yang Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Chang Liu Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Dong Zhao Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Jing Ke Center for Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Introduction Osteoporosis and related fractures commonly exist in patients with type 2 diabetes mellitus (T2DM), which results in a great economic and social burden in the aging society ( 1 ). It has been reported that diabetes mellitus was an

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0449
Volume/Issue:
Volume 10: Issue 10
Open access
Zhiyan Yu Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Yueyue Wu Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Rui Zhang Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Yue Li Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Shufei Zang Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Jun Liu Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai, China

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Introduction Osteoporosis is a systemic bone disease characterized by decrease in bone mass and damage to the microstructure of bone tissue, resulting in increased bone fragility and susceptibility to fracture ( 1 ). Pain due to osteoporosis

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Research Article
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Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-22-0174
Volume/Issue:
Volume 11: Issue 11
Open access
Irasema Mendieta Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

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Rosa Elvira Nuñez-Anita Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás Hidalgo, Morelia, Michoacán, Mexico

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Gilberto Pérez-Sánchez Departmento de Psicoimunología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico

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Lenin Pavón Departmento de Psicoimunología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico

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Alfredo Rodríguez-Cruz Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

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Guadalupe García-Alcocer Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

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Laura Cristina Berumen Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

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. Interleukin-6 induces neuroendocrine differentiation (NED) through suppression of RE-1 silencing transcription factor (REST) . Prostate 2014 74 1086 – 1094 . ( https://doi.org/10.1002/pros.22819 ) 10.1002/pros.22819 24819501 17 Deng X Elzey BD Poulson

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0145
Volume/Issue:
Volume 7: Issue 5
Open access
Rongpeng Gong Medical College, Qinghai University, Xining, People’s Republic of China

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Gang Luo College of Eco-Environmental Engineering, Qinghai University, Xining, People’s Republic of China

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Mingxiang Wang Medical College, Qinghai University, Xining, People’s Republic of China

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Lingbo Ma Medical College, Qinghai University, Xining, People’s Republic of China

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Shengnan Sun Medical College, Qinghai University, Xining, People’s Republic of China

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Xiaoxing Wei Medical College, Qinghai University, Xining, People’s Republic of China

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accelerate the synthesis of factors including leptin, angiotensinogen, tumor necrosis factor α, interleukin 6, plasminogen activator inhibitor 1, transforming growth factor B, adiponectin, adiponectin and resistin. These factors, at least in experimental

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0414
Volume/Issue:
Volume 10: Issue 11
Open access
Qing Zhou Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China

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Li Yong Zhang Department of Thyroid Surgery, Minimal Invasive Center, Fujian Medical University Union Hospital, Fuzhou, China

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Mei Feng Dai Department of Clinical Lab, Fujian Maternity and Child Health Hospital, Fuzhou, China

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Zhen Li Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China

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Chao Chun Zou Department of Endocrinology, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

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Hui Liu Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China

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Introduction Subclinical hypothyroidism has been defined as an elevated serum thyroid-stimulating hormone (TSH) with normal free thyroxine levels ( 1 ). Despite maintaining normal thyroid hormone levels, patients with subclinical

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Research Article
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Thyroid
DOI:
https://doi.org/10.1530/EC-23-0302
Volume/Issue:
Volume 13: Issue 8
Open access
Helle Keinicke Insulin and Device Trial Operations, Novo Nordisk A/S, Søborg, Denmark

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Gao Sun Pharmacology and Histopathology, Novo Nordisk A/S, China

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Caroline M Junker Mentzel Department of Experimental Animal Models, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark

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Merete Fredholm Department of Veterinary Clinical and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark

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Linu Mary John Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Birgitte Andersen Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Kirsten Raun Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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Marina Kjaergaard Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark

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(ER) chaperone 78-kDa glucose-regulated protein ( Hspa5 ), a key regulator of protective responses to the accumulation of misfolded proteins, was upregulated by FGF21 compared to both chow and control ( Fig. 5 ). Interleukin 1b ( Il1b ), macrophage

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0152
Volume/Issue:
Volume 9: Issue 8
Open access
Lars Peter Sørensen
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Tina Parkner Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Esben Søndergaard
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Bo Martin Bibby Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Holger Jon Møller Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Søren Nielsen
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Introduction Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes mellitus (T2DM), but the adverse metabolic consequences of obesity vary between individuals (1) . The mechanisms underlying obesity

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-14-0107
Volume/Issue:
Volume 4: Issue 1
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A Chinoy Royal Manchester Children’s Hospital, Manchester, UK

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M Skae Royal Manchester Children’s Hospital, Manchester, UK

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A Babiker King Abdullah Specialized Children’s Hospital, Riyadh, Saudi Arabia

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D Kendall Royal Preston Hospital, Preston, UK

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M Z Mughal Royal Manchester Children’s Hospital, Manchester, UK

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R Padidela Royal Manchester Children’s Hospital, Manchester, UK

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over-treatment. Inflammatory cytokines may also have a role in this phenomenon. Interleukin (IL)-1β and IL-6 are both pro-inflammatory cytokines whose levels have been shown to increase within hours of infection in crticially ill patients and are

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0234
Volume/Issue:
Volume 6: Issue 8
Open access
Dorte Glintborg Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Magda Lambaa Altinok Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Pernille Ravn Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark

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Kurt Bjerregaard Stage Department of Psychiatry, Odense University Hospital, Odense, Denmark

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Kurt Højlund Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Marianne Andersen Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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plasma cortisol, serum interleukin-1beta and interleukin-6 concentrations in patients with major depressive disorder . Psychiatry Research 2010 1 112 – 115 . ( https://doi.org/10.1016/j.psychres.2009.04.013 ) 19 Zobel AW

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DOI:
https://doi.org/10.1530/EC-18-0077
Volume/Issue:
Volume 7: Issue 3
Open access
Antonina Khoruzhenko Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium
Institute of Molecular Biology and Genetics, NAS of Ukraine, Kiev, Ukraine

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Françoise Miot Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium

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Claude Massart Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium

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Jacqueline Van Sande Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium

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Jacques Emile Dumont Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium

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Renaud Beauwens Laboratory of Physiology and Pharmacology, Université libre de Bruxelles, Brussels, Belgium

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Alain Boom Laboratoire d’Histologie, de Neuroanatomie et de Neuropathologie, Université libre de Bruxelles, Brussels, Belgium

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-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1β and interleukin-6 . Endocrinology 1998 139 3148 – 3156 . ( https://doi.org/10.1210/endo.139.7.6110 ) 15 Herzog V Miller F Membrane retrieval in epithelial cells

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Research Article
DOI:
https://doi.org/10.1530/EC-21-0169
Volume/Issue:
Volume 10: Issue 5
Open access