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Wentao Zhou The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China
Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Tiantao Kuang The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Xu Han Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Wenqi Chen Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Xuefeng Xu The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Wenhui Lou Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Dansong Wang The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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antitumor immune response. A low lymphocyte status usually means that the existing immune system may not exert antitumor effects completely. Tumor-infiltrating lymphocytes (TILs), recruited from circulating lymphocytes, have been found to be important tumor

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K Amrein Thyroid Endocrinology Osteoporosis Institute Dobnig, Graz, Austria
Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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A Papinutti Department of General Surgery, Medical University of Graz, Graz, Austria

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E Mathew Department of General Surgery, Medical University of Graz, Graz, Austria
Department of General Surgery, St. Elisabeth’s Hospital, Graz, Austria

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G Vila Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

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D Parekh Clinician Scientist in Critical Care, Birmingham, Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK

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a wide range of tissues including the innate and adaptive immune system ( 30 , 31 ). The specific nuclear vitamin D receptor (VDR) is widely expressed in many cell types and organs relevant to critically illness ( 32 ) and is known to regulate

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Yali Cheng Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Qiaoying Lv Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Bingying Xie Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Bingyi Yang Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Weiwei Shan Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Chengcheng Ning Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Bing Li Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Liying Xie Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Chao Gu Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Xuezhen Luo Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Xiaojun Chen Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China

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Qin Zhu Department of Pathology, Obstetrics and Gynecology, Hospital of Fudan University, Shanghai, China

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Granulocyte adhesion and diapedesis 4.36516E-08 – Complement system 1.94984E-07 – LXR/RXR activation 2.13796E-05 −1.134 Communication between innate and adaptive immune cells 3.54813E-05 – Acute phase response signaling

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Xuechao Jiang Scientific Research Center, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Pediatric Cardiology, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yonghui Wang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Xiaoying Li Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Leqi He Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Qian Yang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Wei Wang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Jun Liu Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Bingbing Zha Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Laird MR Chen C Sribnaia A Lo R Winsor GL Hancock RE Brinkman FS Lynn DJ. InnateDB: systems biology of innate immunity and beyond – recent updates and continuing curation . Nucleic Acids Research 2013 41 D1228 – D1233 . ( https

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Xiao-Shan Huang Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Ning Dai Zhejiang Chinese Medical University, Hangzhou, China

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Jian-Xia Xu Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Jun-Yi Xiang Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Xiao-Zhong Zheng Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Tian-Yu Ke Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Lin-Ying Ma Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Qi-Hao Shi Zhejiang Chinese Medical University, Hangzhou, China

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Shu-Feng Fan Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Obara-Moszynska M & Niedziela M . The role of the immune system and cytokines involved in the pathogenesis of autoimmune thyroid disease (AITD) . Endokrynologia Polska 2014 65 150 – 155 . ( https://doi.org/10.5603/EP.2014.0021 ) 20 Takasu N

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Nancy J Olsen Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA

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Ann L Benko Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA

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William J Kovacs Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA

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been that androgenic signaling in the immune system was generally suppressive (1, 2, 3) . Our prior studies in men with lupus supported the formulation that attenuated androgen signaling through long AR CAG repeats resulted in increased

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R A M Quax Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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J A M van Laar Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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R van Heerebeek Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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K Greiner Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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E Ben-Chetrit Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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M Stanford Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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G R Wallace Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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F Fortune Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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M Ghabra Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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M Soylu Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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J M W Hazes Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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S W J Lamberts Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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J H Kappen Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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P M van Hagen Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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J W Koper Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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R A Feelders Departments of Internal Medicine, Immunology, St John's Hospital, Department of Medicine, Department of Ophthalmology, Academic Unit of Ophthalmology, Department of Oral Medicine, University Hospital, Department of Ophthalmology, Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands

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GC resistance (31) . Diminished (counterbalancing) cellular effects of GC on the immune system could allow for the development of chronic (auto)-inflammatory processes as in BD. A point of future attention is that in this relatively small group of

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Fei Wu Department of Nuclear Medicine, Yancheng City No. 1 People’s Hospital, Yancheng, China
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Chaoming Mao Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Xiao Mou Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Chengcheng Xu Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Tingting Zheng Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Ling Bu Department of Clinical Medicine, Jiangsu Health Vocational College, Nanjing, China

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Xuan Luo Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Qingyan Lu Department of Laboratory Medicine, Xuzhou Central Hospital, Xuzhou, China

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Xuefeng Wang Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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, tissue homeostasis, development of the immune system, and other systemic effects ( 27 ). In addition to its dispensable roles in the development of T cells and the immune system, mounting evidence has recently suggested that this signaling pathway is

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Jana Ernst Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

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Urszula Grabiec Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

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Kathrin Falk Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

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Faramarz Dehghani Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

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Kristina Schaedlich Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

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Schwarzloh B Rose B Herder C Martin S Algenstaedt P . Immune-mediated activation of the endocannabinoid system in visceral adipose tissue in obesity . Hormone and Metabolic Research 2007 596 – 600 . ( https://doi.org/10.1055/s-2007

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Paolo G Arduino Department of Surgical Sciences, CIR-Dental School, University of Turin, Turin, Italy

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Dora Karimi Department of Surgical Sciences, CIR-Dental School, University of Turin, Turin, Italy

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Federico Tirone Private Practice, Cuneo, Italy

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Veronica Sciannameo Unit of Epidemiology, Regional Health Service ASL TO3, Grugliasco, Turin, Italy

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Fulvio Ricceri Unit of Epidemiology, Regional Health Service ASL TO3, Grugliasco, Turin, Italy

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Marco Cabras Department of Surgical Sciences, CIR-Dental School, University of Turin, Turin, Italy

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Alessio Gambino Department of Surgical Sciences, CIR-Dental School, University of Turin, Turin, Italy

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Davide Conrotto Department of Surgical Sciences, CIR-Dental School, University of Turin, Turin, Italy

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Stefano Salzano Private Practice, Cuneo, Italy

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Mario Carbone Department of Surgical Sciences, CIR-Dental School, University of Turin, Turin, Italy

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Roberto Broccoletti Department of Surgical Sciences, CIR-Dental School, University of Turin, Turin, Italy

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Introduction Oral lichen planus (OLP) is a common immune-mediated mucocutaneous disorder, usually described among females between the fifth and the sixth decades; the estimated worldwide prevalence is reported between 0.22 and 5%, with an

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