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Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands
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arterial hypotension ( 13 ). We aimed to examine whether male and female preterm infants differ in cortisol production and metabolism as assessed by glucocorticoid metabolite excretion in urine, as a possible explanation for the sex differences in
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The University of Liverpool, Brownlow Hill, Liverpool, UK
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screening. CTCAE grade 1–2. Other important considerations; hypophysitis and maintenance glucocorticoid therapy. Management of a life-threateningly unwell patient (CTCAE grade 3–4) Cortisol Features of acute cortisol
The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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retinal, renal and cardiovascular diseases ( 3 ). To achieve the goal of better blood glucose management, a comprehensive understanding of the potential pathological factors is urgently needed. The serum and glucocorticoid inducible kinase-1 (SGK1) is a
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Introduction Prednisolone is a synthetic glucocorticoid that has been used over the last few decades as pharmacotherapy in a plethora of diseases due to its potent antiinflammatory and immunosuppressive properties ( 1 ). Prednisolone is
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Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France
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Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
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was eventually positively diagnosed thanks to liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), which allowed the quantitation of endogenous steroid metabolites and the identification of exogenous glucocorticoid treatment on a
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-transformed concentrations of steroid metabolites (androgens, glucocorticoids and mineralocorticoids) in liver diseases (L1) and with non-liver disease features (L0) patients. Table 3 Ratio of steroid metabolites (enzyme activity): differences between patients
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quality in the offspring during early puberty ( 6 ). There is growing evidence that stressors during pregnancy can impair male reproductive function in offspring. However, the neuroendocrine mechanisms are unclear. Glucocorticoids (GCs) are major
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findings reported were assessed against SGPL1 variant, sex, age of endocrine disease presentation and ethnicity of patient. Specifically, cases (reports) were reviewed for details of adrenal disease, including absence/presence of glucocorticoid
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Division of Medicine, Akershus University Hospital, Lørenskog, Norway
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K.G. Jebsen-Center for Autoimmune Diseases, University of Bergen, Bergen, Norway
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K.G. Jebsen-Center for Autoimmune Diseases, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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sufficient glucocorticoid and mineralocorticoid replacement to suppress ACTH and adrenal androgen production without inducing glucocorticoid side effects ( 4 ). Monitoring of replacement therapy is difficult and lacks standardization in adults. Clinical
Inserm U1016-CNRS UMR8104, Paris, France
Hormonology Department, Cochin Hospital, Paris, France
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Radiology Department, Cochin Hospital, Paris, France
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INSERM, Physiopathologie et Pharmacotoxicologie Placentaire Humaine : Microbiote Pré & Post natal, Paris, France
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Hormonology Department, Cochin Hospital, Paris, France
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UR 7537 BioSTM, Paris, France
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April for UL or BL benign adrenocortical tumors and having a Synacthen® (ACTH 1-24) test during hospitalization in this context were included in our study. CAH, primary hyperaldosteronism and the recent use of exogenous glucocorticoids represented