Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden.
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performance by androgens Testosterone and DHT are the two androgens that clearly bind to the androgen receptor and thereby exert anabolic activity ( Fig. 4 ). Although recent evidence indicates that 11-ketotestosterone and 11-ketodihydrotestosterone
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understanding of the pathology and accumulation of evidence in practice on hyperthyroidism, guidelines for the management of thyrotoxicosis and GD have been formulated or revised in China and abroad ( 1 , 6 , 7 ). In 2007, Chinese scholars formulated the first
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EHESP-School of Public Health, Rennes, France
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Inserm (Institut National de la Santé et de la Recherche Médicale), Irset – Inserm, UMR 1085, Rennes, France
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lifespan, inevitably leading to menopause and infertility. Disturbed establishment of the follicle pool during fetal development may therefore be damaging to fertility in the adult female (reviewed in 1 ). In this review, we discuss the evidence of the
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Department of Clinical Biochemistry, Imperial College Healthcare NHS Trust, London, UK
Department of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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Department of Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK
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until recently, and are often overlooked due to an appropriate fear of Addisonian crises. However, evidence of harm from a minor excess of cortisol is apparent from patients who have subclinical autonomous cortisol production with an associated increase
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Faculty of Life Sciences and Medicine, King’s College London, London, UK
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Faculty of Life Sciences and Medicine, King’s College London, London, UK
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growing evidence base to advocate genetic screening in all PPGL cases ( 10 ). In solitary low-risk PCC in the absence of family history, genetic testing is currently funded by NHS England when diagnosed in patients under 60 years of age or if
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Introduction There is now a large body of evidence – at least in rodents – that the actions of brown adipose tissue (BAT) or the browning of white adipose tissue (WAT) can protect against obesity and related complications ( 1 , 2 , 3 ). The
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the overall results. Moreover, there was no evidence of significant heterogeneity between subgroups with the use of meta-regression analyses. Table 2 Summary risk estimates of the associations between vitamin D level and prostate cancer
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providing evidence for clinical diagnosis and management. Methods and materials The study was approved by Sichuan University of West China Hospital GCP Center – a National Clinical Trials Agency. Written consent has been achieved from all patients
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Faculty of Life Sciences and Medicine, Kings College London, London, UK
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Department of Clinical Biochemistry, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK
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Neuroendocrine Tumour Unit, Kings Health Partners ENETS Centre of Excellence, Denmark Hill, London, UK
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Barts and the London School of Medicine, Centre for Endocrinology, William Harvey Institute, London, UK
Neuroendocrine Tumour Unit, Royal Free Hospital, London, UK
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Faculty of Life Sciences and Medicine, Kings College London, London, UK
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Faculty of Life Sciences and Medicine, School of Life Course Sciences, Obesity Immunometabolism and Diabetes Group, King’s College London, London, UK
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( 10 ). There is speculation that neuroendocrine cells are the origin of lung NENs, but as we do not yet have evidence of the events of early cell change into neoplasm, this cannot be claimed definitively ( 16 ). However, around 25% of lung carcinomas
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trial ( 13 ). Evidence also demonstrated that severe hypoglycemia was strongly associated with hospital mortality, which was considered as an interactive factor for mortality ( 3 , 14 , 15 ). With all those dubious results, we aimed to reassess the