Filter

Refine by collections

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 51 - 60 of 336 items for :

  • central obesity x
Clear All
Luca Persani Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

Search for other papers by Luca Persani in
Google Scholar
PubMed Close
,
Biagio Cangiano Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

Search for other papers by Biagio Cangiano in
Google Scholar
PubMed Close
, and
Marco Bonomi Division of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

Search for other papers by Marco Bonomi in
Google Scholar
PubMed Close

Introduction Central hypothyroidism (CeH) is a rare and heterogenous hypothyroid condition resulting from an insufficient stimulation of an otherwise normal thyroid gland by the hypophyseal thyrotropin hormone (TSH). This loss of central

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0515
Volume/Issue:
Volume 8: Issue 2
Open access
Carla Scaroni Dipartimento di Medicina, U.O.C. Endocrinologia, Università di Padova, Padova, Italy

Search for other papers by Carla Scaroni in
Google Scholar
PubMed Close
,
Nora M Albiger Dipartimento di Medicina, U.O.C. Endocrinologia, Università di Padova, Padova, Italy

Search for other papers by Nora M Albiger in
Google Scholar
PubMed Close
,
Serena Palmieri Department of Clinical Sciences and Community Health, University of Milan, Fondazione IRCCS Cà Granda-Ospedale Maggiore Policlinico, Milan, Italy

Search for other papers by Serena Palmieri in
Google Scholar
PubMed Close
,
Davide Iacuaniello Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Napoli, Italy

Search for other papers by Davide Iacuaniello in
Google Scholar
PubMed Close
,
Chiara Graziadio Department of Experimental Medicine, University La Sapienza, Rome, Italy

Search for other papers by Chiara Graziadio in
Google Scholar
PubMed Close
,
Luca Damiani Department of Medical Sciences, Endocrinology and Internal Medicine Section, University of Ferrara, Ferrara, Italy

Search for other papers by Luca Damiani in
Google Scholar
PubMed Close
,
Marialuisa Zilio Dipartimento di Medicina, U.O.C. Endocrinologia, Università di Padova, Padova, Italy

Search for other papers by Marialuisa Zilio in
Google Scholar
PubMed Close
,
Antonio Stigliano Department of Clinical and Molecular Medicine, Sant’Andrea Hospital, University La Sapienza, Rome, Italy

Search for other papers by Antonio Stigliano in
Google Scholar
PubMed Close
,
Annamaria Colao Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Napoli, Italy

Search for other papers by Annamaria Colao in
Google Scholar
PubMed Close
,
Rosario Pivonello Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Napoli, Italy

Search for other papers by Rosario Pivonello in
Google Scholar
PubMed Close
, and
the Altogether to Beat Cushing’s Syndrome (ABC) study group
Search for other papers by the Altogether to Beat Cushing’s Syndrome (ABC) study group in
Google Scholar
PubMed Close

of the organism to survival ( 1 ). Some common endocrine diseases including obesity, polycystic ovary syndrome (PCOS), poorly controlled diabetes mellitus (DM), chronic alcoholism, and psychiatric disorders may also coincide with HPA axis activation

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-19-0435
Volume/Issue:
Volume 9: Issue 1
Open access
Jana Ernst Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

Search for other papers by Jana Ernst in
Google Scholar
PubMed Close
,
Urszula Grabiec Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

Search for other papers by Urszula Grabiec in
Google Scholar
PubMed Close
,
Kathrin Falk Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

Search for other papers by Kathrin Falk in
Google Scholar
PubMed Close
,
Faramarz Dehghani Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

Search for other papers by Faramarz Dehghani in
Google Scholar
PubMed Close
, and
Kristina Schaedlich Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany

Search for other papers by Kristina Schaedlich in
Google Scholar
PubMed Close

Y Geng Y Zhang Q Huang G Ma Q , et al . DEHP induces obesity and hypothyroidism through both central and peripheral pathways in C3H/He mice . Obesity 2016 368 – 378 . ( https://doi.org/10.1002/oby.21359 ) 16 Schmidt JS Schaedlich

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0548
Volume/Issue:
Volume 9: Issue 2
Open access
Thorben Hoffmann Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany

Search for other papers by Thorben Hoffmann in
Google Scholar
PubMed Close
,
Yousef Ashraf Tawfik Morcos Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany
Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

Search for other papers by Yousef Ashraf Tawfik Morcos in
Google Scholar
PubMed Close
,
Ruth Janoschek Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany

Search for other papers by Ruth Janoschek in
Google Scholar
PubMed Close
,
Eva-Maria Turnwald Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany

Search for other papers by Eva-Maria Turnwald in
Google Scholar
PubMed Close
,
Antje Gerken Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany
Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany

Search for other papers by Antje Gerken in
Google Scholar
PubMed Close
,
Annette Müller Center for Pediatric Pathology at the University Hospital Cologne, Cologne, Germany

Search for other papers by Annette Müller in
Google Scholar
PubMed Close
,
Gerhard Sengle Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany
Center for Biochemistry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany
Cologne Center for Musculoskeletal Biomechanics (CCMB), Cologne, Germany

Search for other papers by Gerhard Sengle in
Google Scholar
PubMed Close
,
Jörg Dötsch Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany

Search for other papers by Jörg Dötsch in
Google Scholar
PubMed Close
,
Sarah Appel Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany

Search for other papers by Sarah Appel in
Google Scholar
PubMed Close
, and
Eva Hucklenbruch-Rother Department of Pediatrics, and Adolescent Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany

Search for other papers by Eva Hucklenbruch-Rother in
Google Scholar
PubMed Close

hypothalamus, where it stimulates appetite-modulating neurons in the arcuate ( 2 ). Clinical studies showed that circulating asprosin levels positively correlated with obesity and type 2 diabetes ( 3 , 4 ). Pre-clinical studies addressing the therapeutic

Article Type:
Research Article
Collections:
Bone and Mineral Metabolism
DOI:
https://doi.org/10.1530/EC-22-0069
Volume/Issue:
Volume 11: Issue 3
Open access
Gaëtan Prévost Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France
Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France

Search for other papers by Gaëtan Prévost in
Google Scholar
PubMed Close
,
Marie Picot Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

Search for other papers by Marie Picot in
Google Scholar
PubMed Close
,
Marie-Anne Le Solliec Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

Search for other papers by Marie-Anne Le Solliec in
Google Scholar
PubMed Close
,
Arnaud Arabo Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

Search for other papers by Arnaud Arabo in
Google Scholar
PubMed Close
,
Hind Berrahmoune Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France
Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France

Search for other papers by Hind Berrahmoune in
Google Scholar
PubMed Close
,
Mouna El Mehdi Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

Search for other papers by Mouna El Mehdi in
Google Scholar
PubMed Close
,
Saloua Cherifi Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

Search for other papers by Saloua Cherifi in
Google Scholar
PubMed Close
,
Alexandre Benani Center for Taste and Feeding Behaviour, CNRS (UMR6265), INRA (UMR1324), Université de Bourgogne-Franche Comté, Dijon , France

Search for other papers by Alexandre Benani in
Google Scholar
PubMed Close
,
Emmanuelle Nédélec Center for Taste and Feeding Behaviour, CNRS (UMR6265), INRA (UMR1324), Université de Bourgogne-Franche Comté, Dijon , France

Search for other papers by Emmanuelle Nédélec in
Google Scholar
PubMed Close
,
Françoise Gobet Department of Anatomopathophysiology, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France

Search for other papers by Françoise Gobet in
Google Scholar
PubMed Close
,
Valéry Brunel Department of Biochemistry, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France

Search for other papers by Valéry Brunel in
Google Scholar
PubMed Close
,
Jérôme Leprince Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

Search for other papers by Jérôme Leprince in
Google Scholar
PubMed Close
,
Hervé Lefebvre Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France
Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France

Search for other papers by Hervé Lefebvre in
Google Scholar
PubMed Close
,
Youssef Anouar Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

Search for other papers by Youssef Anouar in
Google Scholar
PubMed Close
, and
Nicolas Chartrel Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

Search for other papers by Nicolas Chartrel in
Google Scholar
PubMed Close

therapeutic targets for the treatment of diabetes and obesity ( 7 , 8 ). 26RFa (also referred to as QRFP) is a hypothalamic neuropeptide discovered concurrently by us and others ( 9 , 10 , 11 ). Subsequently, 26RFa has been characterized in all the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0247
Volume/Issue:
Volume 8: Issue 7
Open access
Alessandra Gambineri Endocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, Italy

Search for other papers by Alessandra Gambineri in
Google Scholar
PubMed Close
and
Carla Pelusi Endocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, Italy

Search for other papers by Carla Pelusi in
Google Scholar
PubMed Close

and decrease energy expenditure, whereas they have the opposite effect in males. This central sexual dimorphic effect of androgens probably contributes to abdominal obesity, insulin resistance and T2DM in hyperandrogenic and hypogonadic conditions in

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0450
Volume/Issue:
Volume 8: Issue 1
Open access
Laura Chioma Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

Search for other papers by Laura Chioma in
Google Scholar
PubMed Close
,
Carla Bizzarri Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

Search for other papers by Carla Bizzarri in
Google Scholar
PubMed Close
,
Martina Verzani Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

Search for other papers by Martina Verzani in
Google Scholar
PubMed Close
,
Daniela Fava Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy

Search for other papers by Daniela Fava in
Google Scholar
PubMed Close
,
Mariacarolina Salerno Paediatric Endocrinology Unit, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy

Search for other papers by Mariacarolina Salerno in
Google Scholar
PubMed Close
,
Donatella Capalbo Paediatric Endocrinology Unit, Department of Mother and Child, University Hospital Federico II, Naples, Italy

Search for other papers by Donatella Capalbo in
Google Scholar
PubMed Close
,
Chiara Guzzetti Paediatric Endocrine Unit, Paediatric Hospital Microcitemico ‘A. Cao’, AO Brotzu, Cagliari, Italy

Search for other papers by Chiara Guzzetti in
Google Scholar
PubMed Close
,
Laura Penta Pediatric Clinic, Department of Medicine and Surgery, University of Perugia, Perugia, Italy

Search for other papers by Laura Penta in
Google Scholar
PubMed Close
,
Luigi Di Luigi Endocrinology Unit, Department of Movement, Human and Health Sciences, University of Rome ‘Foro Italico’, Rome, Italy

Search for other papers by Luigi Di Luigi in
Google Scholar
PubMed Close
,
Natascia di Iorgi Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy

Search for other papers by Natascia di Iorgi in
Google Scholar
PubMed Close
,
Mohamad Maghnie Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy

Search for other papers by Mohamad Maghnie in
Google Scholar
PubMed Close
,
Sandro Loche Paediatric Endocrine Unit, Paediatric Hospital Microcitemico ‘A. Cao’, AO Brotzu, Cagliari, Italy

Search for other papers by Sandro Loche in
Google Scholar
PubMed Close
, and
Marco Cappa Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

Search for other papers by Marco Cappa in
Google Scholar
PubMed Close

Fernandois D Velasco I Rodriguez-Vazquez E Roa J Vazquez MJ Ruiz-Pino F Rubio M Pineda R Central ceramide signaling mediates obesity-induced precocious puberty . Cell Metabolism 2020 32 951 .e8 – 966.e8 . ( https://doi.org/10.1016/j.cmet.2020

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-21-0650
Volume/Issue:
Volume 11: Issue 2
Open access
Teodoro Durá-Travé Department of Pediatrics, School of Medicine, University of Navarra, Pamplona, Spain
Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain
Navarra Institute for Health Research (IdisNA), Pamplona, Spain

Search for other papers by Teodoro Durá-Travé in
Google Scholar
PubMed Close
,
Fidel Gallinas-Victoriano Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain

Search for other papers by Fidel Gallinas-Victoriano in
Google Scholar
PubMed Close
,
María Malumbres-Chacon Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain

Search for other papers by María Malumbres-Chacon in
Google Scholar
PubMed Close
,
Lotfi Ahmed-Mohamed Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain

Search for other papers by Lotfi Ahmed-Mohamed in
Google Scholar
PubMed Close
,
María Jesús Chueca -Guindulain Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain
Navarra Institute for Health Research (IdisNA), Pamplona, Spain

Search for other papers by María Jesús Chueca -Guindulain in
Google Scholar
PubMed Close
, and
Sara Berrade-Zubiri Department of Pediatrics, Navarra Hospital Complex, Pamplona, Spain
Navarra Institute for Health Research (IdisNA), Pamplona, Spain

Search for other papers by Sara Berrade-Zubiri in
Google Scholar
PubMed Close

Introduction Central precocious puberty (CPP) is defined as the premature activation of the hypothalamic–pituitary–gonadal axis (HPG) with the onset of breast development before 8 years of age in girls and an increase in testicular size in

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0651
Volume/Issue:
Volume 10: Issue 2
Open access
Hong-Fa Yan College of Life and Health Sciences, Northeastern University, Shenyang, China

Search for other papers by Hong-Fa Yan in
Google Scholar
PubMed Close
,
Zhao-Yu Liu College of Life and Health Sciences, Northeastern University, Shenyang, China

Search for other papers by Zhao-Yu Liu in
Google Scholar
PubMed Close
,
Zhi-Ang Guan College of Life and Health Sciences, Northeastern University, Shenyang, China

Search for other papers by Zhi-Ang Guan in
Google Scholar
PubMed Close
, and
Chuang Guo College of Life and Health Sciences, Northeastern University, Shenyang, China

Search for other papers by Chuang Guo in
Google Scholar
PubMed Close

associated oxidative stress are linked to the development of obesity-associated metabolic disturbances, including T2DM ( 5 ), metabolic syndrome ( 6 ), central adiposity and cardiovascular disease ( 7 ). Iron has been shown to be accumulated in the liver and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0054
Volume/Issue:
Volume 7: Issue 4
Open access
Marie Oertel Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany

Search for other papers by Marie Oertel in
Google Scholar
PubMed Close
,
Christian G Ziegler Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany
Department of Internal Medicine III, University Hospital Carl Gustav Carus Dresden, Dresden, Germany

Search for other papers by Christian G Ziegler in
Google Scholar
PubMed Close
,
Michael Kohlhaas Comprehensive Heart Failure Center, Würzburg, Germany

Search for other papers by Michael Kohlhaas in
Google Scholar
PubMed Close
,
Alexander Nickel Comprehensive Heart Failure Center, Würzburg, Germany

Search for other papers by Alexander Nickel in
Google Scholar
PubMed Close
,
Simon Kloock Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany

Search for other papers by Simon Kloock in
Google Scholar
PubMed Close
,
Christoph Maack Comprehensive Heart Failure Center, Würzburg, Germany

Search for other papers by Christoph Maack in
Google Scholar
PubMed Close
,
Vasco Sequeira Comprehensive Heart Failure Center, Würzburg, Germany

Search for other papers by Vasco Sequeira in
Google Scholar
PubMed Close
,
Martin Fassnacht Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany

Search for other papers by Martin Fassnacht in
Google Scholar
PubMed Close
, and
Ulrich Dischinger Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital, University of Würzburg, Würzburg, Germany
Comprehensive Heart Failure Center, Würzburg, Germany

Search for other papers by Ulrich Dischinger in
Google Scholar
PubMed Close

Introduction The prevalence of obesity has almost tripled since 1975, with almost two-thirds of the U.S. population having excess body weight ( 1 , 2 ). The obesity pandemic is particularly devastating in the western hemisphere, with high and

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0398
Volume/Issue:
Volume 13: Issue 3
Open access