Search for other papers by Manjeetkaur Sehemby in
Google Scholar
PubMed
Search for other papers by Prachi Bansal in
Google Scholar
PubMed
Search for other papers by Vijaya Sarathi in
Google Scholar
PubMed
Search for other papers by Ashwini Kolhe in
Google Scholar
PubMed
Search for other papers by Kanchan Kothari in
Google Scholar
PubMed
Search for other papers by Swati Jadhav-Ramteke in
Google Scholar
PubMed
Search for other papers by Anurag R Lila in
Google Scholar
PubMed
Search for other papers by Tushar Bandgar in
Google Scholar
PubMed
Search for other papers by Nalini S Shah in
Google Scholar
PubMed
uterine bleeding ( 2 ). Hyperandrogenic (HA) manifestations include menstrual abnormalities, hirsutism and varying degrees of virilization (temporal balding, deepening of voice, decreased breast size, increased muscle mass, loss of female body contours
Search for other papers by Anello Marcello Poma in
Google Scholar
PubMed
Search for other papers by Riccardo Giannini in
Google Scholar
PubMed
Search for other papers by Paolo Piaggi in
Google Scholar
PubMed
Search for other papers by Clara Ugolini in
Google Scholar
PubMed
Search for other papers by Gabriele Materazzi in
Google Scholar
PubMed
Search for other papers by Paolo Miccoli in
Google Scholar
PubMed
Search for other papers by Paolo Vitti in
Google Scholar
PubMed
Search for other papers by Fulvio Basolo in
Google Scholar
PubMed
cancer models. TIMP1 protein is primarily an inhibitor of secreted and anchored metalloproteinases ( 38 ); however, its upregulation has been reported in several cancers, including melanoma, glioblastoma and breast cancer, in which it was also associated
Search for other papers by Enrique Pedernera in
Google Scholar
PubMed
Search for other papers by Flavia Morales-Vásquez in
Google Scholar
PubMed
Search for other papers by María J Gómora in
Google Scholar
PubMed
Search for other papers by Miguel A Almaraz in
Google Scholar
PubMed
Universidad La Salle, Posgrado de la Facultad de Ciencias Químicas, Ciudad de México, México
Search for other papers by Esteban Mena in
Google Scholar
PubMed
Search for other papers by Delia Pérez-Montiel in
Google Scholar
PubMed
Search for other papers by Elizabeth Rendon in
Google Scholar
PubMed
Search for other papers by Horacio López-Basave in
Google Scholar
PubMed
Search for other papers by Juan Maldonado-Cubas in
Google Scholar
PubMed
Search for other papers by Carmen Méndez in
Google Scholar
PubMed
expression profile in each type of ovarian tumor ( 4 ). Evidence proves the expression of enzymes in several types of tumors involved in the metabolism of steroid hormones. Moreover, their presence in breast and prostate cancer has been extensively explored
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
Search for other papers by Amalie Carlsson in
Google Scholar
PubMed
The Child and Youth Clinic, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Kaspar Sørensen in
Google Scholar
PubMed
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
Search for other papers by Anna-Maria Andersson in
Google Scholar
PubMed
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
Search for other papers by Hanne Frederiksen in
Google Scholar
PubMed
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark
Search for other papers by Anders Juul in
Google Scholar
PubMed
analyses with sex and pubertal stage (3 groups: pre-pubertal, breast/genital stage 2–3 and breast/genital stage 4–5) included as fixed variable and age as continuous variable. No significant interactions were found between sex and puberty in any of the
Search for other papers by Yanfei Chen in
Google Scholar
PubMed
Search for other papers by Mei Li in
Google Scholar
PubMed
Search for other papers by Binrong Liao in
Google Scholar
PubMed
Search for other papers by Jingzi Zhong in
Google Scholar
PubMed
Search for other papers by Dan Lan in
Google Scholar
PubMed
precocious puberty (2015) ( 1 ): (1) breast development before 8 years of age; (2) accelerated linear growth rate (≥6 cm/year); (3) progressive bone age (BA) 1 year more than chronological age (CA); (4) the peak level of luteinizing hormone (LH) (PLH) after
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Felix Haglund in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Gustaf Rosin in
Google Scholar
PubMed
Search for other papers by Inga-Lena Nilsson in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by C Christofer Juhlin in
Google Scholar
PubMed
Search for other papers by Ylva Pernow in
Google Scholar
PubMed
Search for other papers by Sophie Norenstedt in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Andrii Dinets in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Catharina Larsson in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Johan Hartman in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Anders Höög in
Google Scholar
PubMed
breast, where loss of ERB1 is thought to be associated with a poorer prognosis (19, 20) . Results from several studies have indicated a functional association between oestrogen signalling and parathyroid functionality in vitro , with effects on PTH
Structural and Functional Biology Program, Universidade Federal de São Paulo, São Paulo, Brazil
Search for other papers by Erika Urbano Lima in
Google Scholar
PubMed
Structural and Functional Biology Program, Universidade Federal de São Paulo, São Paulo, Brazil
Search for other papers by Ileana G S Rubio in
Google Scholar
PubMed
Post-graduate Program in Interactive Processes of Organs and Systems, Health & Science Institute, Federal University of Bahia, Salvador, Brazil
Search for other papers by Joaquim Custodio Da Silva in
Google Scholar
PubMed
Search for other papers by Ana Luiza Galrão in
Google Scholar
PubMed
Post-graduate Program in Interactive Processes of Organs and Systems, Health & Science Institute, Federal University of Bahia, Salvador, Brazil
Search for other papers by Danielle Pêssoa in
Google Scholar
PubMed
Search for other papers by Taise Cerqueira Oliveira in
Google Scholar
PubMed
Post-graduate Program in Interactive Processes of Organs and Systems, Health & Science Institute, Federal University of Bahia, Salvador, Brazil
Search for other papers by Fabiane Carrijo in
Google Scholar
PubMed
Search for other papers by Igor Silva Campos in
Google Scholar
PubMed
Department of Anatomic Pathology & Legal Medicine, Bahia Federal Medical School, Federal University of Bahia, Salvador, Brazil
Search for other papers by Luciano Fonseca Espinheira in
Google Scholar
PubMed
Search for other papers by Luiz Jose Sampaio in
Google Scholar
PubMed
Search for other papers by Claudio Rogerio Lima in
Google Scholar
PubMed
Division of Genetics, Department of Morphology and Genetics, Genetic Basis of Thyroid Tumors Laboratory, Paulista School of Medicine, Universidade Federal de São Paulo, São Paulo, Brazil
Search for other papers by Janete Maria Cerutti in
Google Scholar
PubMed
Post-graduate Program in Interactive Processes of Organs and Systems, Health & Science Institute, Federal University of Bahia, Salvador, Brazil
Search for other papers by Helton Estrela Ramos in
Google Scholar
PubMed
.2) promoter harbors CpG islands including the first exon and intron ( 13 ). Its epigenetic control has been correlated with tumorigenesis and worse prognosis in uterine, breast, esophageal, gastric, pancreatic and colorectal cancers ( 10 , 11 , 12 , 13
Search for other papers by Stavroula Stavrou in
Google Scholar
PubMed
Search for other papers by Michael Gratz in
Google Scholar
PubMed
Search for other papers by Eileen Tremmel in
Google Scholar
PubMed
Search for other papers by Christina Kuhn in
Google Scholar
PubMed
Search for other papers by Simone Hofmann in
Google Scholar
PubMed
Search for other papers by Helene Heidegger in
Google Scholar
PubMed
Search for other papers by Mina Peryanova in
Google Scholar
PubMed
Search for other papers by Kerstin Hermelink in
Google Scholar
PubMed
Search for other papers by Stefan Hutter in
Google Scholar
PubMed
Search for other papers by Bettina Toth in
Google Scholar
PubMed
Search for other papers by Doris Mayr in
Google Scholar
PubMed
Search for other papers by Sven Mahner in
Google Scholar
PubMed
Search for other papers by Udo Jeschke in
Google Scholar
PubMed
Search for other papers by Aurelia Vattai in
Google Scholar
PubMed
, we analysed the regulation of TAAR1 in breast cancer tissue of primary breast cancer patients and identified that TAAR1 seems to be an independent predictor for breast cancer survival ( 23 ). TAAR1 overexpression (IRS ≥ 6) was associated with a
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Search for other papers by Fernando Aprile-Garcia in
Google Scholar
PubMed
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Search for other papers by María Antunica-Noguerol in
Google Scholar
PubMed
Search for other papers by Maia Ludmila Budziñski in
Google Scholar
PubMed
Search for other papers by Ana C Liberman in
Google Scholar
PubMed
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Search for other papers by Eduardo Arzt in
Google Scholar
PubMed
through different mechanisms depending on cell context. PARP1 induces the transcriptional activity of ligand-activated ER in the breast cancer cells by recluting transcriptional coactivators to ER target genes. PARP1 modulates AR–chromatin interaction in
Search for other papers by Sondra O’Callaghan in
Google Scholar
PubMed
Search for other papers by Hanford Yau in
Google Scholar
PubMed
effect on survival; this has been observed over time ( 4 , 6 ). Despite advances in therapeutics, survival after diagnosis of MAH has not changed over the decades. In the 1980s, patients with bone metastases from breast cancer were observed to survive