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Klaus W Fagerstedt Department of Pathology, University of Helsinki, Helsinki, Finland

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Tom Böhling Department of Pathology, University of Helsinki, Helsinki, Finland
HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland

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Harri Sihto Department of Pathology, University of Helsinki, Helsinki, Finland

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Tarja Salonen HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland

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Fang Zhao Department of Pathology, University of Helsinki, Helsinki, Finland

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Mia Kero Department of Pathology, University of Helsinki, Helsinki, Finland
HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland

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Leif C Andersson Department of Pathology, University of Helsinki, Helsinki, Finland

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Johanna Arola Department of Pathology, University of Helsinki, Helsinki, Finland
HUH Diagnostic Center and Helsinki University Hospital, Helsinki, Finland

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(A and B) Native GNEN-1 cells on the growth surface. The cells grow in clusters adherent to each other and the growth surface. The cells have dendritic-like sprouts from the soma. Clear nucleoli are seen. (C) GNEN-1 cells stained immunohistochemically

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Eric Seidel Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nephrology and Medical Intensive Care, BCRT – Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany
Berlin Institute of Health (BIH), Berlin, Germany
Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany

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Gudrun Walenda Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany

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Clemens Messerschmidt Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany

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Benedikt Obermayer Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany

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Mirko Peitzsch Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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Paal Wallace Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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Rohini Bahethi Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany

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Taekyeong Yoo Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea

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Murim Choi Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea

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Petra Schrade Charité – Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Vegetative Anatomie, Berlin, Germany

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Sebastian Bachmann Charité – Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Vegetative Anatomie, Berlin, Germany

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Gerhard Liebisch Institute of Clinical Chemistry and Laboratory Medicine, Regensburg University Hospital, Regensburg, Germany

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Graeme Eisenhofer Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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Dieter Beule Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany
Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany

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Ute I Scholl Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nephrology and Medical Intensive Care, BCRT – Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany
Berlin Institute of Health (BIH), Berlin, Germany
Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany

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doublings; cPD) is indicated. During long-term treatment, cells initially died, but the population recovered after approximately 30 days. (B) IC 50 of mitotane in 12 clones derived from long-term treated HAC-15 cells vs 6 control clones measured by MTT

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Tao Gao Department of General Practice, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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Rui Liu Department of Oncology. The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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Chunli Li Institute of Life Sciences, Chongqing Medical University, Chongqing, China

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Xinglin Chu Department of General Practice, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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Qiao Guo Department of General Practice, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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Dazhi Ke Department of General Practice, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China

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triglycerides were significantly increased compared to the control group in knockdown liver cells. In addition, it has been found that the activation of farnesoid X receptor leads to upregulation of gene expression encoding fetuin-B ( 8 ). Zhu and other scholars

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Weiwei Liang Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Yilin Zhang Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China

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Yan Guo Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Pengyuan Zhang Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Jiewen Jin Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Hongyu Guan Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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Yanbing Li Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

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-infiltrating immune cells (TIICs) was analyzed by the Tumor Immune Estimation Resource (TIMER). TIMER is a widely used tool for analyzing gene expression and infiltration of six immune cell types (B cells, CD4+ T cells, CD8+ T cells, neutrophils, macrophages, and

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Cleofas Marcial-Medina Departamento de Biologia Celular, Cinvestav-IPN, Mexico City, Mexico

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Alejandra Ordoñez-Moreno Departamento de Biologia Celular, Cinvestav-IPN, Mexico City, Mexico

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Christian Gonzalez-Reyes Departamento de Biologia Celular, Cinvestav-IPN, Mexico City, Mexico

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Pedro Cortes-Reynosa Departamento de Biologia Celular, Cinvestav-IPN, Mexico City, Mexico

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Eduardo Perez Salazar Departamento de Biologia Celular, Cinvestav-IPN, Mexico City, Mexico

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partly inhibited migration induced by OA in MDA-MB-231 cells. Figure 1 FFAR1 and FFAR4 mediate migration induced by OA in breast cancer cells. Panel (A), (B) and (D) Cultures of MDA-MB-231 and MCF-7 cells were treated with DC260126 or AH7614

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Jasmin Asberger Department of Obstetrics and Gynecology, Medical Center – University of Freiburg, Freiburg, Germany
Faculty of Medicine, University of Freiburg, Freiburg, Germany

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Thalia Erbes Department of Obstetrics and Gynecology, Medical Center – University of Freiburg, Freiburg, Germany
Faculty of Medicine, University of Freiburg, Freiburg, Germany

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Markus Jaeger Department of Obstetrics and Gynecology, Medical Center – University of Freiburg, Freiburg, Germany
Faculty of Medicine, University of Freiburg, Freiburg, Germany

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Gerta Rücker Institute of Medical Biometry and Statistics, Medical Center – University of Freiburg, Freiburg, Germany

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Claudia Nöthling Department of Obstetrics and Gynecology, Medical Center – University of Freiburg, Freiburg, Germany
Faculty of Medicine, University of Freiburg, Freiburg, Germany

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Andrea Ritter Department of Obstetrics and Gynecology, Medical Center – University of Freiburg, Freiburg, Germany
Faculty of Medicine, University of Freiburg, Freiburg, Germany

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Kai Berner Department of Obstetrics and Gynecology, Medical Center – University of Freiburg, Freiburg, Germany
Faculty of Medicine, University of Freiburg, Freiburg, Germany

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Ingolf Juhasz-Böss Department of Obstetrics and Gynecology, Medical Center – University of Freiburg, Freiburg, Germany
Faculty of Medicine, University of Freiburg, Freiburg, Germany

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Marc Hirschfeld Department of Obstetrics and Gynecology, Medical Center – University of Freiburg, Freiburg, Germany
Faculty of Medicine, University of Freiburg, Freiburg, Germany
Institute of Veterinary Medicine, Georg-August-University Goettingen, Goettingen, Germany

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Box plot diagram of mRNA expression levels of DDX1 (A), DDX5 (B), DDX17 (C) and ERα (D) in response to endoxifen and fulvestrant. mRNA expression levels of DDX1, DDX5, DDX17 and ESR- α in breast cancer cell lines are displayed under anti

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Chanyang Kim Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, Korea

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Seungjoon Park Department of Pharmacology and Medical Research Center for Bioreaction to ROS and Biomedical Science Institute, School of Medicine, Kyung Hee University, Seoul, Korea

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survival factor for SH-SY5Y cells, we assayed the effect of IGF-1 on cell death induced by MPP + insult. As shown in Fig. 1B , MPP + -induced cell death was partially but significantly attenuated by pretreatment of cells with 10 nM IGF-1. The LDH activity

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Qinglei Yin Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Guangdong Geriatric Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China

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Zhou Jin Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Yulin Zhou Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Dalong Song Guangdong Geriatric Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
Reproductive Medicine Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China

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Chenyang Fu Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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FengJiao Huang Reproductive Medicine Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
Division of Endocrinology, Department of Internal Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

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Shu Wang Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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+ T cells (Supplementary Table 4). The results of hierarchical cluster analyses showed distinguishable lncRNA and mRNA expression profiles between the healthy control CD4+ T cells and GD CD4+ T cells ( Fig. 1A and B ). To visualize the

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Elham Barazeghi Department of Surgical Sciences, Uppsala University, Uppsala University Hospital, Rudbeck Laboratory, Uppsala, Sweden

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Per Hellman Department of Surgical Sciences, Uppsala University, Uppsala University Hospital, Rudbeck Laboratory, Uppsala, Sweden

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Gunnar Westin Department of Surgical Sciences, Uppsala University, Uppsala University Hospital, Rudbeck Laboratory, Uppsala, Sweden

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Peter Stålberg Department of Surgical Sciences, Uppsala University, Uppsala University Hospital, Rudbeck Laboratory, Uppsala, Sweden

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observed in the absence of the primary antibody, and chromogranin A-positive cells in the normal small intestine stained positive for PTPRM ( Fig. 2A and B ). These cells likely represent the enterochromaffin cell of origin of SI-NETs. Figure 1

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Simon Schimmack European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany

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Yongchao Yang European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China
Department of Burns and Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China

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Klaus Felix European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany

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Markus Herbst European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany

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Yixiong Li Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China

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Miriam Schenk European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany

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Frank Bergmann Institute of Pathology, Heidelberg University, Heidelberg, Germany

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Thilo Hackert European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany

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Oliver Strobel European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany

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 G2 43  G3 12 Resection  R0 67  R1 16  R2 6 a Overlapping samples; b FFPE, formalin-fixed paraffin-embedded tissue. pNEN cell lines BON1 and QGP1 The human metastasized adherent

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