Marco Marino
Marco Marino
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Valentina Cirello
Valentina Cirello
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Valentina Gnarini
Valentina Gnarini
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Carla Colombo
Carla Colombo
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Elisa Pignatti
Elisa Pignatti
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Livio Casarini
Livio Casarini
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Chiara Diazzi
Chiara Diazzi
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Vincenzo Rochira
Vincenzo Rochira
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Katia Cioni
Katia Cioni
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Bruno Madeo
Bruno Madeo
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Cesare Carani
Cesare Carani
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Manuela Simoni
Manuela Simoni
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Laura Fugazzola
Laura Fugazzola
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Introduction Thyroid cancers can be well-differentiated, as papillary and follicular subtypes, or poorly differentiated and anaplastic carcinomas. Papillary thyroid carcinoma (PTC) represents up to 80% of all the thyroid cancer cases. Various
Alessandro Brancatella
Alessandro Brancatella
Endocrine Unit 1, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Claudio Marcocci
Claudio Marcocci
Endocrine Unit 2, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Introduction Thyroid hormones are one of the most prescribed drugs in Western countries, mostly for the management of hypothyroidism either spontaneous or after thyroidectomy for benign diseases and differentiated thyroid cancer (DTC). The aim
Yuntao Song
Yuntao Song
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Jiaxin Wang
Jiaxin Wang
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Yanli Zhu
Yanli Zhu
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Pathology, Peking University Cancer Hospital and Institute, Beijing, China
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Guohui Xu
Guohui Xu
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Tianxiao Wang
Tianxiao Wang
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Bin Zhang
Bin Zhang
Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Department of Head and Neck Surgery, Peking University Cancer Hospital and Institute, Beijing, China
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Introduction The incidence-based mortality rates of thyroid cancer continued to increase over the past few decades, with papillary thyroid cancer (PTC) being the most common histology ( 1 ). Recurrent or persistent metastasis of the neck lymph
Mubashir Mulla
Mubashir Mulla
Department of Endocrine Surgery, King College London, King's Health Partners, King's College Hospital, Denmark Hill, London, SE5 9RS, UK
Department of Endocrine Surgery, King College London, King's Health Partners, King's College Hospital, Denmark Hill, London, SE5 9RS, UK
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Department of Endocrine Surgery, King College London, King's Health Partners, King's College Hospital, Denmark Hill, London, SE5 9RS, UK
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Klaus-Martin Schulte
Klaus-Martin Schulte
Department of Endocrine Surgery, King College London, King's Health Partners, King's College Hospital, Denmark Hill, London, SE5 9RS, UK
Department of Endocrine Surgery, King College London, King's Health Partners, King's College Hospital, Denmark Hill, London, SE5 9RS, UK
Department of Endocrine Surgery, King College London, King's Health Partners, King's College Hospital, Denmark Hill, London, SE5 9RS, UK
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Department of Endocrine Surgery, King College London, King's Health Partners, King's College Hospital, Denmark Hill, London, SE5 9RS, UK
Department of Endocrine Surgery, King College London, King's Health Partners, King's College Hospital, Denmark Hill, London, SE5 9RS, UK
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Introduction Papillary thyroid cancer (PTC) is the most common thyroid cancer. Metastases from PTC most commonly involve the cervical lymph nodes (CLNs). The incidence of CLN metastases (CLNM) is reported between 30 and 80% (1, 2) . Some studies
Thomas Crezee
Thomas Crezee
Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands
Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
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Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
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Mirela Petrulea
Mirela Petrulea
Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
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Doina Piciu
Doina Piciu
Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Martin Jaeger
Martin Jaeger
Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Jan W A Smit
Jan W A Smit
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Theo S Plantinga
Theo S Plantinga
Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands
Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Carmen E Georgescu
Carmen E Georgescu
Department of Endocrinology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Endocrinology Clinic, Cluj County Emergency Hospital, Cluj-Napoca, Romania
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Endocrinology Clinic, Cluj County Emergency Hospital, Cluj-Napoca, Romania
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Romana Netea-Maier
Romana Netea-Maier
Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Background In recent years, the incidence of non-medullary thyroid cancer (NMTC) has steadily increased ( 1 , 2 , 3 , 4 ). Although most NMTC patients have a favorable prognosis, 20–30% of patients with locally advanced or metastatic
Jes Sloth Mathiesen
Jes Sloth Mathiesen
Department of ORL Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Jens Peter Kroustrup
Jens Peter Kroustrup
Department of Clinical Medicine and Endocrinology, Aalborg University Hospital, Aalborg, Denmark
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Peter Vestergaard
Peter Vestergaard
Department of Clinical Medicine and Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Steno Diabetes Center North Jutland, Aalborg, Denmark
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Steno Diabetes Center North Jutland, Aalborg, Denmark
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Per Løgstrup Poulsen
Per Løgstrup Poulsen
Department of Internal Medicine and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
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Ulla Feldt-Rasmussen
Ulla Feldt-Rasmussen
Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
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Sten Schytte
Sten Schytte
Department of ORL Head & Neck Surgery, Aarhus University Hospital, Aarhus, Denmark
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Stefano Christian Londero
Stefano Christian Londero
Department of ORL Head & Neck Surgery, Aarhus University Hospital, Aarhus, Denmark
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Henrik Baymler Pedersen
Henrik Baymler Pedersen
Department of ORL Head & Neck Surgery, Aalborg University Hospital, Aalborg, Denmark
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Christoffer Holst Hahn
Christoffer Holst Hahn
Department of ORL Head & Neck Surgery, Copenhagen University Hospital, Copenhagen, Denmark
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Jens Bentzen
Jens Bentzen
Department of Oncology, Herlev Hospital, Herlev, Denmark
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Sören Möller
Sören Möller
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Odense Patient data Explorative Network (OPEN), Odense University Hospital, Odense, Denmark
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Odense Patient data Explorative Network (OPEN), Odense University Hospital, Odense, Denmark
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Mette Gaustadnes
Mette Gaustadnes
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
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Maria Rossing
Maria Rossing
Center for Genomic Medicine, Copenhagen University Hospital, Copenhagen, Denmark
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Finn Cilius Nielsen
Finn Cilius Nielsen
Center for Genomic Medicine, Copenhagen University Hospital, Copenhagen, Denmark
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Kim Brixen
Kim Brixen
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Christian Godballe
Christian Godballe
Department of ORL Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark
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Danish Thyroid Cancer Group (DATHYRCA)
Danish Thyroid Cancer Group (DATHYRCA)
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between January 1960 and December 2014, was constructed through three nationwide registries: the Danish Thyroid Cancer Database, the Danish Cancer Registry and the Danish Pathology Register ( 13 , 14 , 15 ). This has been described in detail previously
Jes Sloth Mathiesen
Jes Sloth Mathiesen
Department of ORL Head & Neck Surgery, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Jens Peter Kroustrup
Jens Peter Kroustrup
Department of Clinical Medicine and Endocrinology, Aalborg University Hospital, Aalborg, Denmark
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Peter Vestergaard
Peter Vestergaard
Department of Clinical Medicine and Endocrinology, Aalborg University Hospital, Aalborg, Denmark
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Kirstine Stochholm
Kirstine Stochholm
Department of Internal Medicine and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
Center for Rare Diseases, Aarhus University Hospital, Aarhus N, Denmark
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Center for Rare Diseases, Aarhus University Hospital, Aarhus N, Denmark
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Per Løgstrup Poulsen
Per Løgstrup Poulsen
Department of Internal Medicine and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
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Ulla Feldt-Rasmussen
Ulla Feldt-Rasmussen
Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
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Sten Schytte
Sten Schytte
Department of ORL Head & Neck Surgery, Aarhus University Hospital, Aarhus, Denmark
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Stefano Christian Londero
Stefano Christian Londero
Department of ORL Head & Neck Surgery, Aarhus University Hospital, Aarhus, Denmark
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Henrik Baymler Pedersen
Henrik Baymler Pedersen
Department of ORL Head & Neck Surgery, Aalborg University Hospital, Aalborg, Denmark
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Christoffer Holst Hahn
Christoffer Holst Hahn
Department of ORL Head & Neck Surgery, Copenhagen University Hospital, Copenhagen, Denmark
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Bjarki Ditlev Djurhuus
Bjarki Ditlev Djurhuus
Department of ORL Head & Neck Surgery, Zealand University Hospital, Køge, Denmark
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Jens Bentzen
Jens Bentzen
Department of Oncology, Herlev Hospital, Herlev, Denmark
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Sören Möller
Sören Möller
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Odense Patient data Explorative Network (OPEN), Odense University Hospital, Odense, Denmark
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Odense Patient data Explorative Network (OPEN), Odense University Hospital, Odense, Denmark
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Mette Gaustadnes
Mette Gaustadnes
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
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Maria Rossing
Maria Rossing
Center for Genomic Medicine, Copenhagen University Hospital, Copenhagen, Denmark
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Finn Cilius Nielsen
Finn Cilius Nielsen
Center for Genomic Medicine, Copenhagen University Hospital, Copenhagen, Denmark
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Kim Brixen
Kim Brixen
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Anja Lisbeth Frederiksen
Anja Lisbeth Frederiksen
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
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Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
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Christian Godballe
Christian Godballe
Department of ORL Head & Neck Surgery, Odense University Hospital, Odense, Denmark
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the Danish Thyroid Cancer Group (DATHYRCA)
the Danish Thyroid Cancer Group (DATHYRCA)
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/17801). Methods The MTC cohort was based on the Danish Cancer Registry, the Danish Pathology Register and the Danish Thyroid Cancer Database, which have prospectively collected data since 1943, 1968 and 1996, respectively. The first year, in which registration
Mahmoud Al-Masri
Mahmoud Al-Masri
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Tawfiq Al-Shobaki
Tawfiq Al-Shobaki
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Hani Al-Najjar
Hani Al-Najjar
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Rafal Iskanderian
Rafal Iskanderian
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Enas Younis
Enas Younis
Department of Internal Medicine, Endocrine, King Hussein Cancer Center, Amman, Jordan
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Niveen Abdallah
Niveen Abdallah
Department of Cell Therapy & Applied Genomics, King Hussein Cancer Center, Amman, Jordan
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Abdelghani Tbakhi
Abdelghani Tbakhi
Department of Cell Therapy & Applied Genomics, King Hussein Cancer Center, Amman, Jordan
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Hussam Haddad
Hussam Haddad
Department of Pathology & Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan
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Mohammad Al-Masri
Mohammad Al-Masri
School of Medicine, University of Jordan, Amman, Jordan
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Zeinab Obeid
Zeinab Obeid
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Awad Jarrar
Awad Jarrar
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Introduction Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer accounting for approximately 85–88% of cases. The incidence of PTC is rapidly increasing, in contrast to other subtypes ( 1 ). The increase in the
Philippe Thuillier
Philippe Thuillier
Department of Endocrinology, University Hospital of Brest, Brest, France
EA GETBO 3878, University Hospital of Brest, Brest, France
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EA GETBO 3878, University Hospital of Brest, Brest, France
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Nathalie Roudaut
Nathalie Roudaut
Department of Endocrinology, University Hospital of Brest, Brest, France
EA GETBO 3878, University Hospital of Brest, Brest, France
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EA GETBO 3878, University Hospital of Brest, Brest, France
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Geneviève Crouzeix
Geneviève Crouzeix
Department of Endocrinology, University Hospital of Brest, Brest, France
EA GETBO 3878, University Hospital of Brest, Brest, France
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EA GETBO 3878, University Hospital of Brest, Brest, France
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Marie Cavarec
Marie Cavarec
EA GETBO 3878, University Hospital of Brest, Brest, France
Department of Nuclear Medicine, University Hospital of Brest, Brest, France
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Department of Nuclear Medicine, University Hospital of Brest, Brest, France
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Philippe Robin
Philippe Robin
EA GETBO 3878, University Hospital of Brest, Brest, France
Department of Nuclear Medicine, University Hospital of Brest, Brest, France
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Department of Nuclear Medicine, University Hospital of Brest, Brest, France
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Ronan Abgral
Ronan Abgral
EA GETBO 3878, University Hospital of Brest, Brest, France
Department of Nuclear Medicine, University Hospital of Brest, Brest, France
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Department of Nuclear Medicine, University Hospital of Brest, Brest, France
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Véronique Kerlan
Véronique Kerlan
Department of Endocrinology, University Hospital of Brest, Brest, France
EA GETBO 3878, University Hospital of Brest, Brest, France
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EA GETBO 3878, University Hospital of Brest, Brest, France
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Pierre-Yves Salaun
Pierre-Yves Salaun
EA GETBO 3878, University Hospital of Brest, Brest, France
Department of Nuclear Medicine, University Hospital of Brest, Brest, France
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Department of Nuclear Medicine, University Hospital of Brest, Brest, France
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clinical thyroid cancer risk factors (age >65 years, male gender), PET–CT parameters (SUVmax median), US characteristics (4 majors malignancy criteria defined as presence of marked hypoechogenicity, irregular margins, more tall than wide dimension and
M Ingenwerth
M Ingenwerth
Institute of Pathology, University Hospital of Essen, University of Duisburg–Essen, Essen, Germany
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T Brandenburg
T Brandenburg
Division of Laboratory Research, Department of Endocrinology, Diabetes and Metabolism and Clinical Chemistry, University Hospital Essen, University of Duisburg-Essen, Germany
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D Führer-Sakel
D Führer-Sakel
Division of Laboratory Research, Department of Endocrinology, Diabetes and Metabolism and Clinical Chemistry, University Hospital Essen, University of Duisburg-Essen, Germany
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M Goetz
M Goetz
Institute of Pathology, University Hospital of Essen, University of Duisburg–Essen, Essen, Germany
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F Weber
F Weber
Department of General, Visceral and Transplantation Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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H Dralle
H Dralle
Department of General, Visceral and Transplantation Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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H-U Schildhaus
H-U Schildhaus
Institute of Pathology, University Hospital of Essen, University of Duisburg–Essen, Essen, Germany
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K W Schmid
K W Schmid
Institute of Pathology, University Hospital of Essen, University of Duisburg–Essen, Essen, Germany
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S Theurer
S Theurer
Institute of Pathology, University Hospital of Essen, University of Duisburg–Essen, Essen, Germany
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thyroid cancer-associated deaths ( 1 , 2 ). They can occur either as part of hereditary syndromes (<30% of all MTC) in multiple endocrine neoplasias (MEN) 2A or 2B with germline mutations in the RET proto-oncogene or as sporadic tumors with approximately
