Section of Pacing and Electrophysiology, Division of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
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Dalian Medical University, Dalian, Liaoning, China
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Dalian Medical University, Dalian, Liaoning, China
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elevated FT3 and (or) FT4 levels with reduced serum TSH level; hypothyroidism as decreased FT3 and (or) FT4 levels with increased TSH level; subclinical hyperthyroidism as decreased serum TSH level and normal serum FT4 and FT3 levels ( 22 ); and subclinical
University of Alcalá, Madrid, Spain
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24-h urine steroid metabolome in 174 newly diagnosed patients with PA, compared to 162 healthy controls, 56 patients with endocrine inactive adrenal adenoma, 104 patients with mild subclinical, and 47 with clinically overt adrenal cortisol excess
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studies have shown associations between overt or subclinical thyroid dysfunction and clinical endpoints such as cardiovascular disease, atrial fibrillation ( 3 ), dyslipidaemia ( 3 ), hypertension ( 4 ), atherosclerosis ( 5 ), type 2 diabetes ( 3 ) and
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to calculate PWV. A PWV value >10 m/s was considered to be an increased PWV. Evaluation of IMT and subclinical atherosclerosis The Q-LAB special application program (Philips, Eindhoven, The Netherlands) was used for duplex scanning of extracranial
The Clatterbridge Cancer Centre, Wirral, UK
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Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK
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. Patients were considered to have had thyroid dysfunction irrespective of their clinical symptoms (i.e. clinical and subclinical biochemical disturbance). The presentation, clinical course (biochemical and symptomatic) and emerging longitudinal biochemical
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’ (toxic adenoma and toxic multinodular goiter) subclinical/mild thyroid hormone excess and the risk of fractures, particularly in postmenopausal women ( 54 , 55 ). Garin et al. evaluated 4936 individuals of 65 years or older monitored for a median of 12
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affected by overt hypothyroidism, 26 females with subclinical hypothyroidism and a group of healthy individuals. In this research, the assessed parameters included the voice self-assessment by VHI-10 questionnaire, the perceptual evaluation with the use of
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, individuals with incidentally discovered adrenal masses and biochemical work-up consistent with subclinical Cushing’s syndrome also have increased cardiometabolic risk ( 2 , 3 , 4 , 5 , 6 ). Even among individuals with biochemical work-up consistent with
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-Albright syndrome (MAS), a sporadic genetic disease, is caused by an activating mutation of GNAS1 for the Gs alpha membrane-associated protein, mediating the TSH-induced and other hormone-induced activation of adenylyl cyclase; subclinical hyperthyroidism can be
Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
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Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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examined age at menarche and findings were diverse, however, with a trend toward later onset in hyperthyroidism and earlier in hypothyroidism ( 5 ). Turning to menopause, a study of 72 cases of subclinical hypothyroidism and controls found no difference in