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Aldo Bonaventura, Fabrizio Montecucco and Franco Dallegri

and compliance with achieving good glycemic control that minimizes the risk of diabetic complications, with a consequent increase in cardiovascular (CV) and neurological morbidities. In this review, based on the material searched for and obtained via

Open access

A Al-Sharefi, P Perros and R A James

-threatening cardiovascular complications due to phaeochromocytoma crises triggered by tumour manipulation, anaesthesia, drugs, pregnancy ( 8 ) or rarely, metastatic disease. Given the uncertainty regarding the value of screening, we reviewed the literature for evidence of

Open access

Ana Carolina de Jesus Paniza, Thais Biude Mendes, Matheus Duarte Borges Viana, Débora Mota Dias Thomaz, Paula B O Chiappini, Gabriel A Colozza-Gama, Susan Chow Lindsey, Marcos Brasilino de Carvalho, Venâncio Avancini Ferreira Alves, Otavio Curioni, André Uchimura Bastos and Janete Maria Cerutti

time of macroscopic examination. To confirm the histological diagnosis and to ensure that representative tumor material was present, the routine hematoxylin and eosin (H&E)-stained sections were reviewed by a specialized pathologist (ACJP). The series

Open access

Joana Simões-Pereira, Daniel Macedo and Maria João Bugalho

analysis. Finally, clinical records were reviewed to evaluate the demographic characteristics, clinical presentation, diagnostic approach, therapeutic modalities and clinical outcome. The results presented herein resulted from a retrospective study based

Open access

M L M Barreto-Chaves, N Senger, M R Fevereiro, A C Parletta and A P C Takano

process, in order to identify possible novel therapeutic targets, is clear. In this context, this review will describe the basic aspects of TH action, focusing on the molecular and cellular mechanisms associated with cardiac hypertrophy, and the

Open access

Frederic Schrøder Arendrup, Severine Mazaud-Guittot, Bernard Jégou and David Møbjerg Kristensen

the bile and later intestines ( 7 ). Several experimental and epidemiological studies have in recent years investigated a possible link between prenatal mild analgesics exposure and effects on the male reproductive system (reviewed in 2 ). Studies

Open access

K Amrein, A Papinutti, E Mathew, G Vila and D Parekh

clinical practice if the on-going trials show benefit. Declaration of interest The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of this review. Funding K A received speaker

Open access

Adriano N Cury, Verônica T Meira, Osmar Monte, Marília Marone, Nilza M Scalissi, Cristiane Kochi, Luís E P Calliari and Carlos A Longui

a fixed dose for all patients, aiming to induce remission of the disease and achieve hypothyroidism or euthyroidism (12) . Patients and methods We reviewed the medical records of 65 patients who were followed between 1985 and 2005 with

Open access

E T Aristizabal Prada and C J Auernhammer

. This review is focused on novel putative targeted therapies for well-differentiated NETs with G1/G2 grading of the GEP system ( 19 , 20 ). We review current preclinical and early clinical data on several putative novel targets and future challenges for

Open access

Legh Wilkinson, Nicolette J D Verhoog and Ann Louw

development of further GC insensitivity. This review begins by briefly describing the types of GC resistance and then discusses reductions in the GRα pool in various pathological and psychological conditions, in terms of acquired GC resistance. Primary focus