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David C Llewellyn Department of Endocrinology ASO/EASO COM, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK

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Rajaventhan Srirajaskanthan Neuroendocrine Tumour Unit, Kings Health Partners ENETS Centre of Excellence, Denmark Hill, London, UK
Faculty of Life Sciences and Medicine, Kings College London, London, UK

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Royce P Vincent Faculty of Life Sciences and Medicine, Kings College London, London, UK
Department of Clinical Biochemistry, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK

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Catherine Guy Department of Cellular Pathology, Royal Sussex County Hospital, Eastern Road, Brighton, UK

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Eftychia E Drakou Department of Clinical Oncology, Guy’s Cancer Centre – Guy’s and St Thomas’ NHS Foundation Trust, Great Maze Pond, London, UK

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Simon J B Aylwin Department of Endocrinology ASO/EASO COM, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK
Neuroendocrine Tumour Unit, Kings Health Partners ENETS Centre of Excellence, Denmark Hill, London, UK

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Ashley B Grossman Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
Barts and the London School of Medicine, Centre for Endocrinology, William Harvey Institute, London, UK
Neuroendocrine Tumour Unit, Royal Free Hospital, London, UK

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John K Ramage Neuroendocrine Tumour Unit, Kings Health Partners ENETS Centre of Excellence, Denmark Hill, London, UK
Faculty of Life Sciences and Medicine, Kings College London, London, UK

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Georgios K Dimitriadis Department of Endocrinology ASO/EASO COM, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK
Faculty of Life Sciences and Medicine, School of Life Course Sciences, Obesity Immunometabolism and Diabetes Group, King’s College London, London, UK

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other PNS. Reported symptoms associated with raised CTN could be diarrhoea, flushing, metabolic alkalosis with hypokalaemia, hypocalcaemia, hypomagnesaemia, hypophosphataemia and hyperglycaemia ( 3 , 20 ). Nozières et al. showed that only one

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Bharat Kumar All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Madhukar Mittal All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Maya Gopalakrishnan All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Mahendra K Garg All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Sanjeev Misra All India Institute of Medical Sciences, Jodhpur, Rajasthan, India

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Bergamaschi L D’Angelo EC Barbieri M Rizzo MR Messina V Maggi P Coppola N et al . Negative impact of hyperglycaemia on tocilizumab therapy in Covid-19 patients . Diabetes and Metabolism 2020 46 403 – 405 . ( https://doi.org/10.1016/j

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Rongpeng Gong Medical College, Qinghai University, Xining, People’s Republic of China

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Gang Luo College of Eco-Environmental Engineering, Qinghai University, Xining, People’s Republic of China

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Mingxiang Wang Medical College, Qinghai University, Xining, People’s Republic of China

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Lingbo Ma Medical College, Qinghai University, Xining, People’s Republic of China

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Shengnan Sun Medical College, Qinghai University, Xining, People’s Republic of China

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Xiaoxing Wei Medical College, Qinghai University, Xining, People’s Republic of China

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. Insulin resistance and hyperglycaemia in cardiovascular disease development . Nature Reviews: Endocrinology 2014 10 293 – 302 . ( https://doi.org/10.1038/nrendo.2014.29 ) 8 Adeva-Andany MM Martínez-Rodríguez J González-Lucán M Fernández

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Yuanyuan Li Department of Endocrinology, Inner Mongolia People’s Hospital, Hohhot, Inner Mongolia, China

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Dongmei Li Department of Endocrinology, Inner Mongolia People’s Hospital, Hohhot, Inner Mongolia, China

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Xingbo Cheng Department of Endocrinology, The First Affiliated Hospital of Soochow University, Suzhou, China

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). After a critical point, insufficient insulin secretion and increased insulin requirements could lead to consequent hyperglycaemia in GDM ( 4 ). Although routine examination (via fasting or postprandial blood glucose) can be fast-evolving, this is rarely

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Hong Wang Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Jie Cao Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Jian-bin Su Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Xue-qin Wang Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Dong-mei Zhang Medical Research Center, Affiliated Hospital 2 of Nantong University, and First People’s Hospital of Nantong City, Nantong, China

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Xiao-hua Wang Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Giugliano D . The role of hyperglycaemia-induced alterations of antithrombin III and factor X activation in the thrombin hyperactivity of diabetes mellitus . Diabetic Medicine 1990 7 343 – 348 . ( https://doi.org/10.1111/j.1464-5491.1990.tb01402.x

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Yuka Goto Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Yoshie Otsuka Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Kenji Ashida Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Ayako Nagayama Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Nao Hasuzawa Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Shimpei Iwata Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Kento Hara Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Munehisa Tsuruta Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Nobuhiko Wada Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Seiichi Motomura Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan
Division of Endocrinology and Metabolism, Diabetes Center, Kurume Medical Center, Kokubu-machi, Kurume-city, Fukuoka, Japan

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Yuji Tajiri Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan
Division of Endocrinology and Metabolism, Diabetes Center, Kurume Medical Center, Kokubu-machi, Kurume-city, Fukuoka, Japan

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Masatoshi Nomura Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition . Diabetologia 2017 60 215 – 225 . ( https://doi.org/10.1007/s00125-016-4157-3 ) 27878313 10.1007/s00125-016-4157-3 22 Jacob S Machann J Rett K

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Ekaterina Koledova Biopharma Global Medical Affairs, General Medicine and Endocrinology, Merck KGaA, Darmstadt, Germany

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George Stoyanov Biopharma Global Medical Affairs, General Medicine and Endocrinology, Merck KGaA, Darmstadt, Germany

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Leroy Ovbude Business & Decision Life Sciences, Brussels, Woluwe-Saint-Lambert, Belgium

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Peter S W Davies Children’s Nutrition Research Centre, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia

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disorder 1 Blood thyroid stimulating hormone increased 1 Death 1 Gynaecomastia 1 Headache 1 Hyperglycaemia 1 Neoplasm recurrence 1 Nephrotic syndrome 1 Scoliosis 1 Sleep apnoea syndrome

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Rongpeng Gong Medical College of Qinghai University, Xining, People’s Republic of China

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Yuanyuan Liu Medical College of Qinghai University, Xining, People’s Republic of China

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Gang Luo Medical College of Qinghai University, Xining, People’s Republic of China

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Jiahui Yin College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China

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Zuomiao Xiao Department of Clinical Laboratory, The Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, China

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Tianyang Hu Precision Medicine Center, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China

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hyperglycaemia in cardiovascular disease development . Nature Reviews: Endocrinology 2014 10 293 – 302 . ( https://doi.org/10.1038/nrendo.2014.29 ) 9 Eckel RH Grundy SM Zimmet PZ . The metabolic syndrome . Lancet 2005 365 1415 – 1428 . ( https

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Alberto Battezzati International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy

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Andrea Foppiani International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy

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Gianfranco Alicandro Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

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Arianna Bisogno Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

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Arianna Biffi Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

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Giorgio Bedogni Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy
Internal Medicine, S. Maria delle Croci Hospital, AUSL Romagna, Ravenna, Italy

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Simona Bertoli International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy
Istituto Auxologico Italiano, IRCCS, Obesity Unit - Laboratory of Nutrition and Obesity Research, Department of Endocrine and Metabolic Diseases, Milan, Italy

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Giulia De Carlo International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy

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Erica Nazzari Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

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Carla Colombo Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy

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hyperglycaemia in cystic fibrosis . European Journal of Pediatrics 1995 154 356 – 361 . ( https://doi.org/10.1007/BF02072102 ) 7 Garagorri JM Rodriguez G Ros L Sanchez A . Early detection of impaired glucose tolerance in patients with cystic fibrosis

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Yanmei Lou Department of Health Management, Beijing Xiaotangshan Hospital, Beijing, People’s Republic of China

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Yanyan Zhang Department of Epidemiology and Health Statistics, Shenzhen University Health Science Center, Shenzhen, Guangdong, People’s Republic of China

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Ping Zhao Department of Health Management, Beijing Xiaotangshan Hospital, Beijing, People’s Republic of China

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Pei Qin Department of Epidemiology and Health Statistics, Shenzhen University Health Science Center, Shenzhen, Guangdong, People’s Republic of China

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Changyi Wang Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, People’s Republic of China

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Jianping Ma Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, People’s Republic of China

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Xiaolin Peng Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, People’s Republic of China

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Hongen Chen Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, People’s Republic of China

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Dan Zhao Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, People’s Republic of China

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Shan Xu Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, People’s Republic of China

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Li Wang Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease, Shenzhen, Guangdong, People’s Republic of China

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Ming Zhang Department of Epidemiology and Health Statistics, Shenzhen University Health Science Center, Shenzhen, Guangdong, People’s Republic of China

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Dongsheng Hu Department of Epidemiology and Health Statistics, Shenzhen University Health Science Center, Shenzhen, Guangdong, People’s Republic of China

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Fulan Hu Department of Epidemiology and Health Statistics, Shenzhen University Health Science Center, Shenzhen, Guangdong, People’s Republic of China

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.88.5.2460 ) 22 World Health Organization & International Diabetes Federation . Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycaemia Report of a WHO/IDF Consultation . World Health Organization , 2006 . 23 Li HY Wei

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