Yuegui Wang
Yuegui Wang
Department of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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Liwei Hong
Liwei Hong
Department of Nuclear Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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Caiyun Yang
Caiyun Yang
Department of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
School of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian, China
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School of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian, China
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Guorong Lv
Guorong Lv
School of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian, China
Quanzhou Medical College, Quanzhou, Fujian, China
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Quanzhou Medical College, Quanzhou, Fujian, China
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Kangjian Wang
Kangjian Wang
Department of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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Xuepeng Huang
Xuepeng Huang
Department of Nuclear Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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Haolin Shen
Haolin Shen
Department of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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triiodothyronine, and thyrotropin receptor antibody Levels of free triiodothyronine (FT3), free thyroxine (FT4), and thyrotropin receptor antibody (TRAb) in patients' venous blood were measured using an electroluminescent immunoassay (Beckman, DXI800) after
Yun Cai
Yun Cai
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Jieni Yan
Jieni Yan
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Yong Gu
Yong Gu
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Heng Chen
Heng Chen
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Yang Chen
Yang Chen
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Xinyu Xu
Xinyu Xu
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Mei Zhang
Mei Zhang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Liping Yu
Liping Yu
Barbara Davis Center for Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA
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Xuqin Zheng
Xuqin Zheng
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Tao Yang
Tao Yang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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.2%) – <0.0001* <0.0001* <0.0001* >0.05* – – FT3 (pmol/L) 13.3 ± 11.5 4.63 ± 2.50 5.37 ± 4.28 – <0.0001 ‡ <0.0001 § <0.0001 § >0.05 § – – FT4 (pmol/L) 33.9 ± 26.0 15.3 ± 8.85 20.9 ± 14.0 – <0.0001 ‡ <0
W J Bom
W J Bom
Department of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands
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F B M Joosten
F B M Joosten
Department of Radiology, Rijnstate Hospital, Arnhem, the Netherlands
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M M G J van Borren
M M G J van Borren
Department of Clinical Chemistry, Rijnstate Hospital, Arnhem, the Netherlands
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E P Bom
E P Bom
Department of Radiology, Rijnstate Hospital, Arnhem, the Netherlands
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R R J P van Eekeren
R R J P van Eekeren
Department of Surgery, Rijnstate Hospital, Arnhem, the Netherlands
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H de Boer
H de Boer
Department of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands
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–50 mm, (3) degree of cystic degeneration <50%, (4) serum TSH, FT4, and FT3 levels within the normal range, and (5) benign cytology or histology. The study was approved by the local ethical committee, and all patients gave their informed consent
T Grimmichova
T Grimmichova
Institute of Endocrinology, Narodni, Prague, Czech Republic
2nd Department of Internal Medicine, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University in Prague, Srobarova, Prague, Czech Republic
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2nd Department of Internal Medicine, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University in Prague, Srobarova, Prague, Czech Republic
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M Haluzik
M Haluzik
Institute of Endocrinology, Narodni, Prague, Czech Republic
Diabetes Centre, Institute for Clinical and Experimental Medicine (IKEM), Videnska, Prague, Czech Republic
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Diabetes Centre, Institute for Clinical and Experimental Medicine (IKEM), Videnska, Prague, Czech Republic
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K Vondra
K Vondra
Institute of Endocrinology, Narodni, Prague, Czech Republic
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P Matucha
P Matucha
Institute of Endocrinology, Narodni, Prague, Czech Republic
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M Hill
M Hill
Institute of Endocrinology, Narodni, Prague, Czech Republic
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hypo- or hyperthyroidism were re-checked for glucose disorders after reaching a euthyroid state. Basal blood samples for the determination of TSH, fT4, fT3, anti-thyroid peroxidase antibodies (anti-TPO), anti-thyroglobulin (anti-Tg), thyrotropin
Xuechao Jiang
Xuechao Jiang
Scientific Research Center, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Pediatric Cardiology, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Department of Pediatric Cardiology, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Yonghui Wang
Yonghui Wang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Xiaoying Li
Xiaoying Li
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Leqi He
Leqi He
Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Qian Yang
Qian Yang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Wei Wang
Wei Wang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Jun Liu
Jun Liu
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Bingbing Zha
Bingbing Zha
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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of GD patients. Subject Age range (years) Duration of clinical manifestation (days) Hormone Autoantibody FT3 (pmol/L) FT4 (pmol/L) TSH (mIU/L) TGAb (IU/mL) TPOAb (IU/mL) TRAb (IU/L) 1 60–65 30 37
M Krause
M Krause
Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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H Frederiksen
H Frederiksen
Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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K Sundberg
K Sundberg
Center of Fetal Medicine and Pregnancy, Department of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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F S Jørgensen
F S Jørgensen
Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark
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L N Jensen
L N Jensen
Center of Fetal Medicine and Pregnancy, Department of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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P Nørgaard
P Nørgaard
Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark
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C Jørgensen
C Jørgensen
Center of Fetal Medicine and Pregnancy, Department of Obstetrics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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P Ertberg
P Ertberg
Fetal Medicine Unit, Department of Obstetrics and Gynecology, Copenhagen University Hospital, Hvidovre, Denmark
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J H Petersen
J H Petersen
Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Section of Biostatistics, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark
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Section of Biostatistics, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark
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U Feldt-Rasmussen
U Feldt-Rasmussen
Department of Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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A Juul
A Juul
Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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K T Drzewiecki
K T Drzewiecki
Department of Plastic Surgery, Breast Surgery and Burns Treatment, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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N E Skakkebaek
N E Skakkebaek
Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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A M Andersson
A M Andersson
Department of Growth and Reproduction & International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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exception of two samples, which were analyzed for thyroid hormones in March 2017. The thyroid hormones triiodothyronine (T 3 ), free triiodothyronine (fT 3 ), thyroxine (T 4 ) and free thyroxine (fT 4 ) were measured by competitive electrochemiluminescence
Kusum Lata
Kusum Lata
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Pinaki Dutta
Pinaki Dutta
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Subbiah Sridhar
Subbiah Sridhar
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Minakshi Rohilla
Minakshi Rohilla
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Anand Srinivasan
Anand Srinivasan
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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G R V Prashad
G R V Prashad
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Viral N Shah
Viral N Shah
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Anil Bhansali
Anil Bhansali
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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vacutainers at the initial visit. Each blood sample was analysed for TSH, free tri-iodothyronine (FT 3 ), free T 4 (FT 4 ) and anti-TPO by electro-chemiluminescence immunoassay (ELECSYS-2010, Roche–Hitachi Diagnostics). The reference range for the above
Qingrong Pan
Qingrong Pan
Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
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Shuxin Gao
Shuxin Gao
Department of General Practice, Cangzhou Central Hospital, Cangzhou, Hebei Province, China
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Xia Gao
Xia Gao
Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
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Ning Yang
Ning Yang
Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
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Zhi Yao
Zhi Yao
Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
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Yanjin Hu
Yanjin Hu
Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
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Li Miao
Li Miao
Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
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Zhe Chen
Zhe Chen
Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
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Guang Wang
Guang Wang
Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Beijing, China
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normal ranges. The normal values for TSH, free triiodothyronine (FT3) and free thyroxine (FT4) were 0.55–4.78 μIU/mL, 2.3–4.2 pg/mL and 8.9–17.6 pg/mL, respectively. Exclusion criteria were as follows: patients under treatment with thyroxine, or anti
Ayse Nurcan Cebeci
Ayse Nurcan Cebeci
Paediatric Endocrinology, Department of Friedrich-Alexander University Hospital, Erlangen, Germany
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Vera Schempp
Vera Schempp
Paediatric Endocrinology, University Hospital, Bonn, Germany
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Katharina Förtsch
Katharina Förtsch
Paediatric Endocrinology, University Hospital, Düsseldorf, Germany
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Bettina Gohlke
Bettina Gohlke
Paediatric Endocrinology, University Hospital, Bonn, Germany
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Michaela Marx
Michaela Marx
Paediatric Endocrinology, Department of Friedrich-Alexander University Hospital, Erlangen, Germany
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Helmuth-Guenther Dörr
Helmuth-Guenther Dörr
Paediatric Endocrinology, Department of Friedrich-Alexander University Hospital, Erlangen, Germany
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Joachim Woelfle
Joachim Woelfle
Paediatric Endocrinology, Department of Friedrich-Alexander University Hospital, Erlangen, Germany
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‘block and replace’ varied between doctors in each centre. The remission of the disease was defined as the absence of symptoms of hyperthyroidism along with normalisation of laboratory measurements (fT3, fT4, and TSH concomitantly negative TSHRab) at
Ru-Xuan Zhao
Ru-Xuan Zhao
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Ting-Ting Shi
Ting-Ting Shi
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Sha Luo
Sha Luo
Department of Nuclear Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Yun-Fu Liu
Yun-Fu Liu
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Zhong Xin
Zhong Xin
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Jin-Kui Yang
Jin-Kui Yang
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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drug use, and history of smoking were recorded. Clinical data including serum free triiodothyronine 3 (FT3), free triiodothyronine 4 (FT4), thyroid-stimulating hormone (TSH), and thyrotropin receptor antibody (TRAb) levels were measured to assess
