Xiuhua Liao
Xiuhua Liao
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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Suqin Zhu
Suqin Zhu
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Shumin Qiu
Shumin Qiu
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Hua Cao
Hua Cao
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Wenwen Jiang
Wenwen Jiang
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Huiling Xu
Huiling Xu
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Yan Sun
Yan Sun
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
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Beihong Zheng
Beihong Zheng
Center of Reproductive Medicine, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China
Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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Fujian Maternal-Fetal Clinical Medicine Research Center, Fuzhou, China
Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect, Fuzhou, China
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). Mitochondria are important organelles that play a crucial role in energy production, metabolism, and cell apoptosis. Mitochondrial dynamics, including mitochondrial fusion and fission, are essential for maintaining normal mitochondrial function. Moreover
Zhen-yu Song
Zhen-yu Song
Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China
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Qiuming Yao
Qiuming Yao
Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China
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Zhiyuan Zhuo
Zhiyuan Zhuo
Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China
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Zhe Ma
Zhe Ma
Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China
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Gang Chen
Gang Chen
Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China
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an important role in cellular proliferation ( 4 ), differentiation, apoptosis ( 5 ), angiogenesis ( 6 ) and metastasis ( 7 ). All these processes may regulate the development and progression of cancer. A number of researches have been done to
Ann-Kristin Picke
Ann-Kristin Picke
Institute of Comparative Molecular Endocrinology, Ulm University, Ulm, Germany
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Graeme Campbell
Graeme Campbell
Institute of Biomechanics, TUHH Hamburg University of Technology, Hamburg, Germany
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Nicola Napoli
Nicola Napoli
Diabetes and Bone Network, Department Endocrinology and Diabetes, University Campus Bio-Medico of Rome, Rome, Italy
Division of Bone and Mineral Diseases, Washington University in St Louis, St Louis, Missouri, USA
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Division of Bone and Mineral Diseases, Washington University in St Louis, St Louis, Missouri, USA
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Lorenz C Hofbauer
Lorenz C Hofbauer
Department of Medicine III & Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany
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Martina Rauner
Martina Rauner
Department of Medicine III & Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany
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macrophages and reduced switch into anti-inflammatory M2 macrophages. (4) The network of osteocytes is reduced due to an increased apoptosis rate. They increase their expression of sclerostin, an inhibitor of osteoblast function, and RANKL, a promoter of
Rong Xu
Rong Xu
Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Difei Lian
Difei Lian
Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Yan Xie
Yan Xie
Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Lin Mu
Lin Mu
Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Yali Wu
Yali Wu
Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Zhilei Chen
Zhilei Chen
Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Baoyu Zhang
Baoyu Zhang
Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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Beijing Key Laboratory of Diabetes Research and Care, Beijing, China
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proliferation of osteoblasts through inhibiting the expression of Runx2 and Osterix (Runx2 and Osterix are key transcriptional regulators of osteoblast differentiation) but also negatively affect their activity, viability, and apoptosis, resulting in a decrease
Jian Ding
Jian Ding
Department of Obstetrics and Gynecology, Maternal and Child Health Care Hospital of Shandong Province, Jinan, Shandong Province, China
Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China
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Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China
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Yan Kang
Yan Kang
Department of Obstetrics and Gynecology, Maternal and Child Health Care Hospital of Shandong Province, Jinan, Shandong Province, China
Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China
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Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China
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Yuqin Fan
Yuqin Fan
Department of Obstetrics and Gynecology, Maternal and Child Health Care Hospital of Shandong Province, Jinan, Shandong Province, China
Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China
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Department of Obstetrics and Gynecology, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province, China
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Qi Chen
Qi Chen
Department of Obstetrics and Gynecology, Zoucheng People’s Hospital, Zoucheng, Shandong Province, China
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beneficial effects in various cardiovascular diseases ( 12 ). For instance, in rat model of PE, RESV was reported to reduce blood pressure ( 13 ), as well as inhibit trophoblast apoptosis through oxidative stress ( 14 ). In a pregnant mouse model with reduced
Flavia Letícia Martins Peçanha
Flavia Letícia Martins Peçanha
Instituto de Bioquímica Médica Leopoldo de Meis, Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, Rio de Janeiro, Brazil
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Reinaldo Sousa dos Santos
Reinaldo Sousa dos Santos
Instituto de Bioquímica Médica Leopoldo de Meis, Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, Rio de Janeiro, Brazil
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Wagner Seixas da-Silva
Wagner Seixas da-Silva
Instituto de Bioquímica Médica Leopoldo de Meis, Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, Rio de Janeiro, Brazil
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hyperthyroid animals. Excessive TH signaling is known to induce cell apoptosis in several cell lines through the activation of different mechanisms ( 65 , 66 , 67 , 68 ). On the other hand, several studies have demonstrated that the presence of HK bound to
Brenda Anguiano
Brenda Anguiano
Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
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Carlos Montes de Oca
Carlos Montes de Oca
Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
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Evangelina Delgado-González
Evangelina Delgado-González
Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
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Carmen Aceves
Carmen Aceves
Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
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or thyroxine; TRAMP, transgenic adenocarcinoma of the mouse prostate. TRH, thyrotropin releasing hormone; VEGFA, vascular endothelial growth factor; XIAP, X-linked inhibitor of apoptosis. Prostate pathologies Benign prostate
Xianghe Chen
Xianghe Chen
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xinyu Zeng
Xinyu Zeng
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xiao Qiu
Xiao Qiu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Chi Liu
Chi Liu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Pengcheng Lu
Pengcheng Lu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Ziming Shen
Ziming Shen
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xiangxiang Zhou
Xiangxiang Zhou
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Kang Yang
Kang Yang
Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China
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fibrosis in T2DM mice. Studies have found that with the development of T2DM, renal tissue will appear obvious fibrosis in the later stage, while hyperglycemia leads to internal environmental inflammation, oxidative stress and apoptosis, which increases the
Jian Gong
Jian Gong
School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, China
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Yinjuan Lv
Yinjuan Lv
School of Basic Medicine, Hubei University of Chinese Medicine, Wuhan, China
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Yuhao Meng
Yuhao Meng
Hubei University of Chinese Medicine, Wuhan, China
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Weiheng Zhang
Weiheng Zhang
Hubei University of Chinese Medicine, Wuhan, China
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Xiaocui Jiang
Xiaocui Jiang
Hubei University of Chinese Medicine, Wuhan, China
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Min Xiao
Min Xiao
Laboratory Animal Center, Hubei University of Chinese Medicine, Wuhan, China
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of the male offspring's reproductive organs ( 4 ). In animal models, prenatal stress led to apoptosis of testicular cells and reduced sperm quality and fertility in offspring rats ( 5 ). Maternal stress in sheep during late pregnancy affects sperm
Clara Lundetoft Clausen
Clara Lundetoft Clausen
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital, Copenhagen, Denmark
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Trine Holm Johannsen
Trine Holm Johannsen
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
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Linda Maria Hilsted
Linda Maria Hilsted
Department of Clinical Biochemistry, Copenhagen University Hospital, Copenhagen, Denmark
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Niels Erik Skakkebæk
Niels Erik Skakkebæk
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
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Pal Bela Szecsi
Pal Bela Szecsi
Department of Clinical Biochemistry, Holbæk Hospital, Holbæk, Denmark
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Lise Pedersen
Lise Pedersen
Department of Clinical Biochemistry, Holbæk Hospital, Holbæk, Denmark
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Thomas Benfield
Thomas Benfield
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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-derived growth factor-AA (PDGF-AA); PDGF-AB/BB; transforming growth factor-α (TGFA); tumor necrosis factor-α (TNFA); TNF-related apoptosis inducing ligand (TRAIL/TNFSF10); and vascular endothelial growth factor (VEGF). Statistics Data processing and
