Avinaash Maharaj
Avinaash Maharaj
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Ruth Kwong
Ruth Kwong
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Jack Williams
Jack Williams
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Christopher Smith
Christopher Smith
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Helen Storr
Helen Storr
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Ruth Krone
Ruth Krone
Birmingham Children’s Hospital, Birmingham, UK
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Debora Braslavsky
Debora Braslavsky
Centro de Investigaciones Endocrinológicas ‘Dr. Cesar Bergadá’ (CEDIE) – CONICET – FEI – División de Endocrinología, Hospital de Niños ‘Ricardo Gutiérrez’, Buenos Aires, Argentina
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Maria Clemente
Maria Clemente
Paediatric Endocrinology, Growth and Development Research Unit, Vall d’Hebron Research Institute (VHIR), Hospital Vall d’Hebron, CIBERER, Instituto de Salud Carlos III, Barcelona, Spain
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Nanik Ram
Nanik Ram
Department of Endocrinology, The Aga Khan University Hospital, Karachi, Pakistan
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Indraneel Banerjee
Indraneel Banerjee
Department of Paediatric Endocrinology, Royal Manchester Children’s Hospital, Manchester, UK
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Semra Çetinkaya
Semra Çetinkaya
Health Sciences University, Dr. Sami Ulus Obstetrics and Gynaecology, Children’s Health and Disease Education and Research Hospital, Ankara, Turkey
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Federica Buonocore
Federica Buonocore
Genetics and Genomic Medicine Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK
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Tülay Güran
Tülay Güran
Department of Paediatric Endocrinology and Diabetes, Marmara University, School of Medicine, Istanbul, Turkey
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John C Achermann
John C Achermann
Genetics and Genomic Medicine Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, University College London, London, UK
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Louise Metherell
Louise Metherell
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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Rathi Prasad
Rathi Prasad
Centre for Endocrinology, John Vane Science Centre, Queen Mary University of London, London, UK
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NCI-H295R (adrenocortical carcinoma) cells increases S1P expression and steroidogenesis ( 32 ). Conversely, sphingolipid intermediates ceramide and sphingosine diminish steroidogenesis, with sphingosine purported to directly attenuate the activity of
Marianna Viukari
Marianna Viukari
Endocrinology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
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Helena Leijon
Helena Leijon
Department of Pathology, University of Helsinki and HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland
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Tiina Vesterinen
Tiina Vesterinen
Department of Pathology, University of Helsinki and HUS Diagnostic Center, Helsinki University Hospital, Helsinki, Finland
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Sanni Söderlund
Sanni Söderlund
Endocrinology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
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Päivi Hämäläinen
Päivi Hämäläinen
Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
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Iina Yliaska
Iina Yliaska
Medical Research Center Oulu, Oulu University Hospital and Research Unit of Internal Medicine, University of Oulu, Oulu, Finland
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Päivi Rautiainen
Päivi Rautiainen
Joint Municipal Authority for North Karelia Social and Health Services (Siun Sote), Joensuu, Finland
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Reeta Rintamäki
Reeta Rintamäki
Department of Endocrinology and Clinical Nutrition, Kuopio University Hospital, Kuopio, Finland
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Minna Soinio
Minna Soinio
Department of Endocrinology, Turku University Hospital, Turku, Finland
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Ilkka Pörsti
Ilkka Pörsti
Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland
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Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland
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Pasi I Nevalainen
Pasi I Nevalainen
Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
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Niina Matikainen
Niina Matikainen
Endocrinology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
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excluded from the study, one due to the finding of adrenocortical carcinoma, two due to nonrepresentative samples, and one due to the patient not having undergone adrenalectomy but postmortem obduction. In addition, 22 samples from a previous prospective
