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, 18 ). A small internal study of a single tertiary care centre in Lombardy, Italy, suggested a more than 5 times higher incidence of COVID-19 infection in a subgroup of 61 patients with Cushing’s disease (CD) and 15 patients with active
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. Journal of Clinical Endocrinology and Metabolism 2019 104 1978 – 1988 . ( https://doi.org/10.1210/jc.2018-01979 ) 31 Colao A De Block C Gaztambide MS Kumar S Seufert J Casanueva FF . Managing hyperglycemia in patients with Cushing’s disease
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mutation carriers were identified. Finally, Chasseloup et al. studied germline CDKN1B loss-of-function variants in mostly pediatric Cushing’s disease patients with or without a MEN4 phenotype ( 40 ). Five variants of interest were found. Genetic
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Green Templeton College, University of Oxford, Oxford, UK
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review of literature . Medicine 2019 98 e17772. ( https://doi.org/10.1097/MD.0000000000017772 ) 7 Gezer E Selek A Cetinarslan B Canturk Z Tarkun I Ceylan S The coexistence of infundibular pituicytoma and Cushing’s disease due to
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patients with Cushing’s disease due to excess pituitary ACTH or Cushing’s syndrome caused by ectopic ACTH production. It is important, however, to reiterate that many genes that are transcriptionally regulated by ACTH encode factors which are subject to non
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catecholamine excess or MRI of pituitary gland (in order to exclude Cushing’s disease) are useful in establishing the cause of hypokalemia. Moreover, an abdominal CT scan should be performed if clinical and laboratory features of VIPoma are present, such as
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Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland
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causes of NAFLD. Hormone Gland of origin Example of disease Cortisol - Pituitary gland (ACTH) - Adrenal gland (cortisol) - Cushing’s disease - Cushing’s syndrome - Exogenous corticoid administration Thyroxine (T4
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of fracture, independently from BMD ( 36 , 37 ), as often seen in some endocrine disorders, namely acromegaly, Cushing’s disease, hyperparathyroidism and hyperthyroidism ( 38 , 39 , 40 ). Another classical example is glucocorticoid
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diseases (e.g. Cushing’s disease, hyperthyroidism or primary hyperparathyroidism), inflammatory diseases (e.g. rheumatoid arthritis or inflammatory bowel diseases) or medication (e.g. glucocorticoids or cancer treatments) ( 15 ). Vertebral fractures
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pregnancy because of potential adverse effects on mother and fetus. Salivary cortisol/cortisone has emerged as an alternative tool in the assessment of cortisol exposure and is used as a diagnostic tool in Cushing’s disease ( 111 ) and more recently