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Maurício Martins da Silva Laboratory of Endocrine Physiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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Lueni Lopes Felix Xavier Laboratory of Endocrine Physiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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Carlos Frederico Lima Gonçalves Laboratory of Endocrine Physiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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Ana Paula Santos-Silva Laboratory of Endocrine Physiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil
NUMPEX, Campus Duque de Caxias, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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Francisca Diana Paiva-Melo Laboratory of Endocrine Physiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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Mariana Lopes de Freitas Laboratory of Endocrine Physiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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Rodrigo Soares Fortunato Laboratory of Molecular Radiobiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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Leandro Miranda-Alves Laboratory of Endocrine Physiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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Andrea Claudia Freitas Ferreira Laboratory of Endocrine Physiology, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil
NUMPEX, Campus Duque de Caxias, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

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negative association with free T4 levels ( 8 ), thus suggesting an impact also in thyroid axis. Furthermore, BPA has been shown to increase oxidative stress, leading to oxidative damage of proteins, lipids and nucleic acids in liver, central nervous system

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0348
Volume/Issue:
Volume 7: Issue 11
Open access
Caroline Serrano-Nascimento Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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Rafael Barrera Salgueiro Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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Kaio Fernando Vitzel Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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Thiago Pantaleão Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Vânia Maria Corrêa da Costa Carlos Chagas Filho Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Maria Tereza Nunes Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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.05 vs 5× (ANOVA, Student–Newman–Keuls). Effects of maternal IE exposure on thyroid oxidative stress Both doses of IE treatment (5× and 50×) augmented the oxidative stress in the thyroid gland of exposed rat dams. Indeed, as shown in Fig

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0106
Volume/Issue:
Volume 6: Issue 7
Open access
Neil R Chappell Reproductive Endocrinology and Infertility Division, Department of Obstetrics and Gynecology, Baylor College of Medicine and Family Fertility Center, Texas Children’s Hospital, Houston, Texas, USA

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Beth Zhou Reproductive Endocrinology and Infertility Division, Department of Obstetrics and Gynecology, Baylor College of Medicine and Family Fertility Center, Texas Children’s Hospital, Houston, Texas, USA

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Amy K Schutt Reproductive Endocrinology and Infertility Division, Department of Obstetrics and Gynecology, Baylor College of Medicine and Family Fertility Center, Texas Children’s Hospital, Houston, Texas, USA

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William E Gibbons Reproductive Endocrinology and Infertility Division, Department of Obstetrics and Gynecology, Baylor College of Medicine and Family Fertility Center, Texas Children’s Hospital, Houston, Texas, USA

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Chellakkan S Blesson Reproductive Endocrinology and Infertility Division, Department of Obstetrics and Gynecology, Baylor College of Medicine and Family Fertility Center, Texas Children’s Hospital, Houston, Texas, USA

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mechanisms in PCOS oocytes. Our recent study in androgen programmed neonatal ovaries showed similar mitochondrial damage possibly due to increased oxidative stress with increased basal ATP production ( 49 ). It is possible that persistent exposure to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0553
Volume/Issue:
Volume 9: Issue 3
Open access
Shane M Regnier Committee on Molecular Metabolism and Nutrition, Chicago, Illinois, USA
Pritzker School of Medicine, Chicago, Illinois, USA
University of Chicago, Chicago, Illinois, USA

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Andrew G Kirkley University of Chicago, Chicago, Illinois, USA
Committee on Molecular Pathogenesis and Molecular Medicine, Chicago, Illinois, USA

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Daniel Ruiz Committee on Molecular Metabolism and Nutrition, Chicago, Illinois, USA
University of Chicago, Chicago, Illinois, USA

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Wakanene Kamau University of Chicago, Chicago, Illinois, USA

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Qian Wu Wadsworth Center, New York Department of Health, Albany, New York, USA

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Kurunthachalam Kannan Wadsworth Center, New York Department of Health, Albany, New York, USA

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Robert M Sargis Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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preference and energy expenditure High dietary sugar consumption is a potent metabolic stressor with the capacity to disrupt insulin–glucose homeostasis and promote obesity development ( 25 ). Mice fed an HSD with TF exhibited reduced weight gain relative

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0320
Volume/Issue:
Volume 7: Issue 1
Open access
B Fabre Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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G Maccallini Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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A Oneto Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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D Gonzalez Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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V Hirschler Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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C Aranda Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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G Berg Clinical Biochemistry Department, Hospital Carlos G. Durand Laboratory, TCba Salguero Laboratory, Hospital Carlos G. Durand Nutrition Unit, INFIBIOC, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina

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Introduction Saliva is a useful sample as a source of hormones for the diagnosis of different diseases, particularly in pediatric patients and aged individuals; the collection of saliva offers a noninvasive and stress-free alternative compared to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0024
Volume/Issue:
Volume 1: Issue 2
Open access
Mette Marie Baunsgaard Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark

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Anne Sophie Lind Helligsoe Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark

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Louise Tram Henriksen Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark

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Torben Stamm Mikkelsen Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark

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Michael Callesen Department of Paediatrics, Odense University Hospital, Odense, Funen, Denmark

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Britta Weber The Danish Center for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark

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Henrik Hasle Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark

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Niels Birkebæk Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark

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summary, our study illustrates that there is room for improvements regarding the diagnostic process of GHD and stresses the need for GH testing in adult radiated brain tumor survivors with less than two hormonal deficiencies in addition to GHD

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0365
Volume/Issue:
Volume 12: Issue 2
Open access
Stan Ursem Department of Clinical Chemistry, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, Vrije Universiteit Amsterdam, Endocrine Laboratory, Amsterdam, Netherlands

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Vito Francic Division of Endocrinology and Diabetology, Department of Internal Medicine, Endocrinology Lab Platform, Medical University of Graz, Graz, Austria

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Martin Keppel University Institute for Medical and Chemical Laboratory Diagnostics, Paracelsus Medical University, Salzburg, Austria

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Verena Schwetz Division of Endocrinology and Diabetology, Department of Internal Medicine, Endocrinology Lab Platform, Medical University of Graz, Graz, Austria

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Christian Trummer Division of Endocrinology and Diabetology, Department of Internal Medicine, Endocrinology Lab Platform, Medical University of Graz, Graz, Austria

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Marlene Pandis Division of Endocrinology and Diabetology, Department of Internal Medicine, Endocrinology Lab Platform, Medical University of Graz, Graz, Austria

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Felix Aberer Division of Endocrinology and Diabetology, Department of Internal Medicine, Endocrinology Lab Platform, Medical University of Graz, Graz, Austria

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Martin R Grübler Division of Endocrinology and Diabetology, Department of Internal Medicine, Endocrinology Lab Platform, Medical University of Graz, Graz, Austria

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Nicolas D Verheyen Division of Cardiology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Winfried März Synlab Academy, Synlab Holding Germany GmbH, München, Germany

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Andreas Tomaschitz Specialist Clinic of Rehabilitation Bad Gleichenberg, Bad Gleichenberg, Austria

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Stefan Pilz Division of Endocrinology and Diabetology, Department of Internal Medicine, Endocrinology Lab Platform, Medical University of Graz, Graz, Austria

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Barbara Obermayer-Pietsch Division of Endocrinology and Diabetology, Department of Internal Medicine, Endocrinology Lab Platform, Medical University of Graz, Graz, Austria

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Annemieke C Heijboer Department of Clinical Chemistry, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, Vrije Universiteit Amsterdam, Endocrine Laboratory, Amsterdam, Netherlands
Department of Clinical Chemistry, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Endocrine Laboratory, Amsterdam, Netherlands

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large fraction of circulating PTH is oxidised, this total PTH (tPTH) may rather reflect oxidative stress-related pathology ( 9 ). Tepel et al. showed that haemodialysis patients with higher n-oxPTH concentrations had an increased survival. Per contra

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0097
Volume/Issue:
Volume 8: Issue 5
Open access
Riying Liang Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China
Department of Ultrasound, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China

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Meijun Wang Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Chang Fu Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Hua Liang Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Hongrong Deng Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Ying Tan Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Fen Xu Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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Mengyin Cai Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China

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play a vital role in maintaining the balance of blood glucose, blood lipid, and energy metabolism ( 14 ). The protective effects of SIRT1, such as regulation of energy metabolism, anti-fibrosis, and anti-oxidative stress, have been detected in various

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0294
Volume/Issue:
Volume 9: Issue 9
Open access
Joanna Klubo-Gwiezdzinska National Institute of Health, NIDDK, Office 10 Center Drive, Bethesda, Maryland, USA
Division of Endocrinology, Department of Medicine, Medstar Washington Hospital Center, Washington Hospital Center, Northwest, Washington, District of Columbia, USA

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John Costello Jr Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

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Kirk Jensen Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

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Aneeta Patel Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

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Rok Tkavc Department of Pathology, Uniformed Services University of the Health Sciences, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA

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Douglas Van Nostrand Division of Endocrinology, Department of Medicine, Medstar Washington Hospital Center, Washington Hospital Center, Northwest, Washington, District of Columbia, USA

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Kenneth D Burman Division of Endocrinology, Department of Medicine, Medstar Washington Hospital Center, Washington Hospital Center, Northwest, Washington, District of Columbia, USA

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Leonard Wartofsky Division of Endocrinology, Department of Medicine, Medstar Washington Hospital Center, Washington Hospital Center, Northwest, Washington, District of Columbia, USA

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Vasyl Vasko Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

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measured the comet score in 200 randomly selected cells per slide. Results were expressed as the percentage of each stage of comets per slide. Results WR-1065 did not protect thyroid cancer cells against DNA damage in an oxidative stress model

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0138
Volume/Issue:
Volume 6: Issue 7
Open access
Milena Kloter Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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Claudia Gregoriano Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Ellen Haag Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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Alexander Kutz Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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Beat Mueller Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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Philipp Schuetz Medical University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland
Faculty of Medicine, University of Basel, Basel, Switzerland

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endocrine stress response and stabilize blood hemostasis through vasoconstrictive effects and the overwhelming immune response through immunomodulatory effects ( 5 ). While pharmacological treatment of sepsis patients with vasopressin did not appear to lower

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0211
Volume/Issue:
Volume 10: Issue 9
Open access