Bruno Donadille
Bruno Donadille
Service d’Endocrinologie et Médecine de la Reproduction, Centre de Référence des Maladies Endocrines Rares de la Croissance, Hôpital Saint Antoine, Groupe Hospitalier Universitaire Est, AP-HP, Paris, France
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Muriel Houang
Muriel Houang
Service d’Explorations Fonctionnelles Endocriniennes, Centre de Référence des Maladies Endocrines Rares de la Croissance, Hôpital Trousseau, Groupe Hospitalier Universitaire Est, AP-HP, Paris, France
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Irène Netchine
Irène Netchine
Service d’Explorations Fonctionnelles Endocriniennes, Centre de Référence des Maladies Endocrines Rares de la Croissance, Hôpital Trousseau, Groupe Hospitalier Universitaire Est, AP-HP, Paris, France
Université Pierre et Marie Curie, Sorbonne Université, Paris, France
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
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Jean-Pierre Siffroi
Jean-Pierre Siffroi
Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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INSERM UMR_S933, Paris, France
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Sophie Christin-Maitre
Sophie Christin-Maitre
Service d’Endocrinologie et Médecine de la Reproduction, Centre de Référence des Maladies Endocrines Rares de la Croissance, Hôpital Saint Antoine, Groupe Hospitalier Universitaire Est, AP-HP, Paris, France
Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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severe form of HSD3B2 mutation, male patients present neonatal salt wasting, as well as disorders of sexual development (DSD), with micropenis and severe hypospadias. The external genitalia morphogenesis is impaired due to the diminished testosterone
Shota Dzemaili
Shota Dzemaili
University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland
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Jitske Tiemensma
Jitske Tiemensma
University of California Merced, Psychological Science, Merced, CA, USA
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Richard Quinton
Richard Quinton
Department of Endocrinology, Institute for Human Genetics, University of Newcastle-upon-Tyne, Newcastle-upon-Tyne, United Kingdom
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Nelly Pitteloud
Nelly Pitteloud
Endocrinology, Diabetes & Metabolism Service of the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
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Diane Morin
Diane Morin
University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland
Faculty of Nursing Science, Laval University, Québec City, Canada
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Faculty of Nursing Science, Laval University, Québec City, Canada
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Andrew A Dwyer
Andrew A Dwyer
University of Lausanne, Institute of Higher Education and Research in Healthcare, Lausanne, Switzerland
Endocrinology, Diabetes & Metabolism Service of the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
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Endocrinology, Diabetes & Metabolism Service of the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
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types of congenital hypogonadism (14 with CHH, 7 with 46XX gonadal dysgenesis) whose SF-36 scores were quite similar. A subset of these patients completed the Female Sexual Function Index revealing impaired sexual desire, arousal, lubrication, orgasm and
Lawrence D Hayes
Lawrence D Hayes
Active Ageing Research Group, Department of Medical and Sport Sciences, University of Cumbria, Lancaster, UK
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Peter Herbert
Peter Herbert
School of Sport, Health and Outdoor Education, Trinity Saint David, University of Wales, Carmarthen, UK
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Nicholas F Sculthorpe
Nicholas F Sculthorpe
Institute of Clinical Exercise and Health Science, University of the West of Scotland, Hamilton, UK
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Fergal M Grace
Fergal M Grace
Faculty of Health, Federation University, Victoria, Australia
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. ( doi:10.1210/jcem.84.10.6079 ) 23 Khoo J Tian HH Tan B Chew K Ng CS Leong D Teo RC Chen RY. Comparing effects of low- and high-volume moderate-intensity exercise on sexual function and testosterone in obese men
Jan-Bernd Stukenborg
Jan-Bernd Stukenborg
NORDFERTIL Research Lab Stockholm, Pediatric Endocrinology Unit, Department of Women’s and Children’s Health, Karolinska Institutet and University Hospital, Stockholm, Sweden
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Kirsi Jahnukainen
Kirsi Jahnukainen
NORDFERTIL Research Lab Stockholm, Pediatric Endocrinology Unit, Department of Women’s and Children’s Health, Karolinska Institutet and University Hospital, Stockholm, Sweden
Division of Haematology-Oncology and Stem Cell Transplantation, Children’s Hospital, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Division of Haematology-Oncology and Stem Cell Transplantation, Children’s Hospital, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Marsida Hutka
Marsida Hutka
MRC Centre for Reproductive Health, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK
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Rod T Mitchell
Rod T Mitchell
MRC Centre for Reproductive Health, The Queen’s Medical Research Institute, The University of Edinburgh, Edinburgh, UK
Edinburgh Royal Hospital for Sick Children, Edinburgh, UK
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Edinburgh Royal Hospital for Sick Children, Edinburgh, UK
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presence of functioning somatic cell populations. This unique testicular microenvironment which includes the SSC, supporting somatic cell populations and the presence of specific growth factors is known as the germ-stem cell niche. Cell populations deemed
Pravik Solanki
Pravik Solanki
Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
Alfred Health, Melbourne, Victoria, Australia
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Alfred Health, Melbourne, Victoria, Australia
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Beng Eu
Beng Eu
Prahran Market Clinic, Victoria, Australia
Department of General Practice, Melbourne Medical School, The University of Melbourne, Victoria, Australia
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Department of General Practice, Melbourne Medical School, The University of Melbourne, Victoria, Australia
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Jeremy Smith
Jeremy Smith
Faculty of Science, University of Western Australia, Perth, Australia
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Carolyn Allan
Carolyn Allan
Hudson Institute of Medical Research, Melbourne, Victoria, Australia
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Kevin Lee
Kevin Lee
Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
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differences in sperm concentration Shephard et al. 1977( 69 ) Cross-sectional Four bodybuilding previous users aged 23–52 years Methandrostenolone 10–15 mg/day 7–10 months 2 weeks–7 months since cessation Sexual function Serum
Anita Hokken-Koelega
Anita Hokken-Koelega
Erasmus University Medical Centre, Rotterdam, The Netherlands
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Aart-Jan van der Lely
Aart-Jan van der Lely
Erasmus University Medical Centre, Rotterdam, The Netherlands
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Berthold Hauffa
Berthold Hauffa
University Children’s Hospital, Essen, Germany
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Gabriele Häusler
Gabriele Häusler
Medical University and General Hospital of Vienna, Vienna, Austria
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Gudmundur Johannsson
Gudmundur Johannsson
Sahlgrenska University Hospital, Göteborg, Sweden
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Mohamad Maghnie
Mohamad Maghnie
Istituto Giannina Gaslini, University of Genova, Genova, Italy
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Jesús Argente
Jesús Argente
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
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Jean DeSchepper
Jean DeSchepper
University Hospital Brussels, Brussels, Belgium
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Helena Gleeson
Helena Gleeson
Queen Elizabeth Hospital, Birmingham, UK
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John W Gregory
John W Gregory
Cardiff University School of Medicine, Cardiff, UK
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Charlotte Höybye
Charlotte Höybye
Department of Molecular Medicine and Surgery, Karolinska Institute and Department of Endocrinology, Metabolism and Diabetology, Karolinska University Hospital, Stockholm, Sweden
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Fahrettin Keleştimur
Fahrettin Keleştimur
Department of Endocrinology, School of Medicine, Erciyes University, Kayseri, Turkey
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Anton Luger
Anton Luger
Sahlgrenska University Hospital, Göteborg, Sweden
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Hermann L Müller
Hermann L Müller
Department of Pediatrics, Klinikum Oldenburg, Medical Campus University Oldenburg, Oldenburg, Germany
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Sebastian Neggers
Sebastian Neggers
University Children’s Hospital, Essen, Germany
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Vera Popovic-Brkic
Vera Popovic-Brkic
Belgrade University School of Medicine, Belgrade, Serbia
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Eleonora Porcu
Eleonora Porcu
University of Bologna, Bologna, Italy
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Lars Sävendahl
Lars Sävendahl
Department of Women’s and Children’s Health, Karolinska Institutet, and Pediatric Endocrinology Unit, Karolinska University Hospital, Stockholm, Sweden
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Stephen Shalet
Stephen Shalet
The Christie Hospital, Manchester, UK
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Bessie Spiliotis
Bessie Spiliotis
University of Patras School of Medicine, Patras, Greece
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Maithé Tauber
Maithé Tauber
Hôpital des Enfants, Toulouse, France
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Introduction Monumental changes in human development occur during adolescence. Teens undergo a period of physical growth and sexual maturation, and pronounced cognitive development, and are eagerly forming their own identities to achieve
Elizabeth Micks
Elizabeth Micks
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Greta B Raglan
Greta B Raglan
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Jay Schulkin
Jay Schulkin
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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related steroid receptors. Research in preterm and normal labor has highlighted the impact of progesterone on immune functioning. Bringing two worlds together Biochemists continue to elucidate the mechanisms of action of different progestins in order to
Silvia Ciancia
Silvia Ciancia
Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium
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Vanessa Dubois
Vanessa Dubois
Basic and Translational Endocrinology (BaTE), Department of Basic and Applied Medical Sciences, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium
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Martine Cools
Martine Cools
Department of Internal Medicine and Pediatrics, Ghent University, Pediatric Endocrinology Service, Ghent University Hospital, Ghent, Belgium
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functioning and well-being, and as such, this represents an additional diagnostic landmark. In these adolescents, puberty suppression, once the diagnosis of persistent GD is confirmed, serves multiple goals: it can provide time and mental space for the
Mei Li
Mei Li
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Yanfei Chen
Yanfei Chen
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Binrong Liao
Binrong Liao
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jing Tang
Jing Tang
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jingzi Zhong
Jingzi Zhong
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Dan Lan
Dan Lan
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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luteinizing hormone (LH) and follicle stimulating hormone (FSH). Central precocious puberty (CPP) is a common pediatric endocrine disease due to premature reactivation of the HPG axis leading to the development of secondary sexual characteristics before the
André Marques-Pinto
André Marques-Pinto
Serviço de Endocrinologia, Departamento de Endocrinologia, Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
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Davide Carvalho
Davide Carvalho
Serviço de Endocrinologia, Departamento de Endocrinologia, Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
Serviço de Endocrinologia, Departamento de Endocrinologia, Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
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Serviço de Endocrinologia, Departamento de Endocrinologia, Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
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diseases and a consequent decline in reproductive function worldwide (3) . Given the short time frame, genetic changes cannot explain it. Thus, environmental substances may be accountable for the observed trends (4, 5) . Indeed, both humans and wildlife
