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Department of Public Health, Environmental Medicine, University of Southern Denmark, Odense, Denmark
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Department of Obstetrics and Gynecology, Herlev Hospital, Copenhagen, Denmark
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Department of Medical Endocrinology, Odense University Hospital, Odense, Denmark
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Hans Christian Andersen Children’s Hospital, Odense University Hospital, Odense, Denmark
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population Participants were included from Odense Child Cohort (OCC), an on-going prospective, observational cohort consisting of mothers and their children. Inclusion criteria of OCC were residence in the Municipality of Odense and newly discovered
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, 39 , 40 , 41 ) in women with PCOS. Although, VAI is not validated in paediatric population, many studies report its usefulness in predicting metabolic syndrome in children ( 42 ) and its association with insulin resistance, adipokines, and
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countries ( 1 ) and the lowest in Japan. Despite the advent of glucocorticoid replacement therapy in the early 1950s, life expectancy remains lower than in the general population ( 2 ), with increased morbidity and impaired quality of life ( 3 , 4
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. However, for the several admissions every week to the children’s wards seen during a personal 3-month attachment to the paediatric department of an east London teaching hospital as a medical student in the late 1950s, this condition (incidence up to 20
Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France
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Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France
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Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France
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Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France
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Department of Endocrinology and Reproductive Medicine, AP-HPIE3M, Hôpital Pitié-Salpêtrière, ICAN, Paris, France
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Department of Endocrinology and Reproductive Medicine, AP-HPIE3M, Hôpital Pitié-Salpêtrière, ICAN, Paris, France
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Centre for Rare Gynecological Disorders, Hospital Universitaire Necker-Enfants Malades, Paediatric Endocrinology, Gynaecology and Diabetology, AP-HP, Université de Paris, Paris, France
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Department of Paediatric Endocrinology, Gynaecology, and Diabetology, AP-HP, Necker-Enfants Malades University Hospital, IMAGINE Institute affiliate, Paris, France
Centre for Rare Gynecological Disorders, Hospital Universitaire Necker-Enfants Malades, Paediatric Endocrinology, Gynaecology and Diabetology, AP-HP, Université de Paris, Paris, France
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study did not find any ovarian abnormality at birth ( 14 , 22 ), feeding the pregnant rats with a high-galactose diet depleted the oocyte population in the embryos ( 17 ). In women, few studies on ovarian histology described a wide range from normal to
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Steno Diabetes Center North Jutland, Aalborg University Hospital, Aalborg, Denmark
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Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
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5529 women in the study population. Information on maternal height and pre-pregnancy weight was used to calculate pre-pregnancy BMI (body weight (in kg) divided by the height (in m 2 )). Concerning thyroid function tests, the free T4 index (ft4 index
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studied in general population with regard to predicting follicular reserve and follicle recruitment ( 29 ) and correlates well with antral follicle count in adults ( 30 ) and adolescents ( 31 ). In younger paediatric patients, reports on this correlation
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St.Anna Kinderspital, Medical University of Vienna, Vienna, Austria
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with CAH were collected in a standardized database. Later, the German Society for Paediatric Endocrinology and Diabetology (DGKED) took responsibility for the registry (DGKED-QS)). Until now 49 centers have participated in the DGKED-QS registry. Centers
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Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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Emma Children’s Hospital, Amsterdam UMC, Department of Pediatrics, Amsterdam, The Netherlands
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University Hospital Würzburg, Department of Nuclear Medicine, Würzburg, Germany
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shows that even in a population at high risk for developing DTC a structured surveillance program will not have an effect on 10-year DTC-specific survival rates. There is no difference in survival of DTC between patients who undergo surveillance and
Department of Endocrinology, St James’s Hospital, Dublin, Ireland
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Department of Endocrinology, University of Manchester, Manchester, UK
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Department of Paediatric Endocrinology & Diabetes, Newcastle-upon-Tyne Hospitals, Newcastle upon Tyne, UK
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Endocrine Research Group, Institute of Genetic Medicine, University of Newcastle-upon-Tyne, Newcastle upon Tyne, UK
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Introduction Delayed puberty is defined by the absence of testicular development 2.5 s.d. later than the population mean – typically 14 years of age in males ( 1 ). Although the majority of cases at age 14 have constitutional delay (CDP