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Yumei Zhai
Yumei Zhai
The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China
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Haiming Fu
Haiming Fu
Department of Clinical Laboratory, Baotou Maternal and Child Health Center, Baotou, Inner Mongolia Autonomous Region, P.R. China
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Yu Li
Yu Li
The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China
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Siyuan Li
Siyuan Li
The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China
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Wenchen Zhang
Wenchen Zhang
The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China
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Jianwei Yue
Jianwei Yue
The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China
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Zichao Wang
Zichao Wang
The Second Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia Autonomous Region, P.R. China
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. In a cross-sectional study focusing on the association between different IR surrogates and with nonalcoholic fatty liver, TyG-BMI and METS-IR demonstrated the strongest association with nonalcoholic fatty liver disease, along with the best predictive
Yang Yu
Yang Yu
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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Hairong Hao
Hairong Hao
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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Linghui Kong
Linghui Kong
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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Jie Zhang
Jie Zhang
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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Feng Bai
Feng Bai
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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Fei Guo
Fei Guo
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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Pan Wei
Pan Wei
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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Rui Chen
Rui Chen
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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Wen Hu
Wen Hu
Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China
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de Borst MH Wolak-Dinsmore J Connelly MA Bakker SJL & Dullaart RPF . Non-alcoholic fatty liver disease and risk of incident Type 2 diabetes: role of circulating branched-chain amino acids . Nutrients 2019 11 . ( https://doi.org/10
Devis Pascut
Devis Pascut
Fondazione Italiana Fegato – ONLUS, Trieste, Italy
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Sofia Tamini
Sofia Tamini
Istituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-endocrinological Research, Milan and Piancavallo (VB), Italy
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Silvia Bresolin
Silvia Bresolin
Laboratory of Onco-Hematology, Department of Women’s and Children’s Health, University of Padova, Padova, Italy
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Pablo Giraudi
Pablo Giraudi
Fondazione Italiana Fegato – ONLUS, Trieste, Italy
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Giuseppe Basso
Giuseppe Basso
Laboratory of Onco-Hematology, Department of Women’s and Children’s Health, University of Padova, Padova, Italy
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Alessandro Minocci
Alessandro Minocci
Istituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-endocrinological Research, Milan and Piancavallo (VB), Italy
Division of Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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Division of Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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Claudio Tiribelli
Claudio Tiribelli
Fondazione Italiana Fegato – ONLUS, Trieste, Italy
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Graziano Grugni
Graziano Grugni
Istituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-endocrinological Research, Milan and Piancavallo (VB), Italy
Division of Auxology, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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Division of Auxology, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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Alessandro Sartorio
Alessandro Sartorio
Istituto Auxologico Italiano, IRCCS, Experimental Laboratory for Auxo-endocrinological Research, Milan and Piancavallo (VB), Italy
Division of Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
Division of Auxology, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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Division of Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
Division of Auxology, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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non-alcoholic fatty liver disease, both in children and adults, has been found in PWS ( 12 , 13 ). In recent years, growing evidences have identified miRNAs as important regulators of cellular pathways. They may affect lipid metabolism ( 14
Zheng Chen
Zheng Chen
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Haixia Zeng
Haixia Zeng
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Qiulan Huang
Qiulan Huang
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Cuiping Lin
Cuiping Lin
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Xuan Li
Xuan Li
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Shaohua Sun
Shaohua Sun
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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Jian-ping Liu
Jian-ping Liu
Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China
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, diabetes mellitus (DM), nonalcoholic fatty liver disease (NAFLD), cardiovascular disease, endometrial lesions, and hypertension during pregnancy ( 2 , 3 , 4 , 5 ). The etiology of PCOS is unclear at present, though environmental and genetic factors are
Peter Wolf
Peter Wolf
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
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Yvonne Winhofer
Yvonne Winhofer
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
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Martin Krššák
Martin Krššák
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
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High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
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Michael Krebs
Michael Krebs
Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
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Canali G Bertoli L Zoppini G Barbieri E Targher G. Nonalcoholic fatty liver disease is associated with left ventricular dysfunciton in patients with type 2 diabetes . Diabetes Care 2012 35 389 – 395 . ( doi:10.2337/dc11
Fabian Eichelmann
Fabian Eichelmann
Department of Epidemiology, Nutrition, Immunity and Metabolism Start-up Lab, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany
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Cornelia Weikert
Cornelia Weikert
Department of Food Safety, Federal Institute for Risk Assessment
Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany
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Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany
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Romina di Giuseppe
Romina di Giuseppe
Institute of Epidemiology, Christian-Albrechts University Kiel, Kiel, Germany
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Ronald Biemann
Ronald Biemann
Department for Clinical Chemistry and Pathobiochemistry, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
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Berend Isermann
Berend Isermann
Department for Clinical Chemistry and Pathobiochemistry, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
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Matthias B Schulze
Matthias B Schulze
Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany
German Center of Diabetes Research (DZD), München-Neuherberg, Germany
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German Center of Diabetes Research (DZD), München-Neuherberg, Germany
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Heiner Boeing
Heiner Boeing
Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany
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Krasimira Aleksandrova
Krasimira Aleksandrova
Department of Epidemiology, Nutrition, Immunity and Metabolism Start-up Lab, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany
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patients with biopsy-proven nonalcoholic fatty liver disease . Scandinavian Journal of Gastroenterology 2011 46 91 – 97 . ( doi:10.3109/00365521.2010.516452 ) 11 Adrych K Stojek M Smoczynski M Sledzinski T Sylwia SW
Xiaomin Nie
Xiaomin Nie
Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China
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Yiting Xu
Yiting Xu
Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China
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Xiaojing Ma
Xiaojing Ma
Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China
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Yun Shen
Yun Shen
Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China
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Yufei Wang
Yufei Wang
Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China
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Yuqian Bao
Yuqian Bao
Department of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital; Shanghai Clinical Center for Diabetes; Shanghai Key Clinical Center for Metabolic Disease; Shanghai Diabetes Institute; Shanghai Key Laboratory of Diabetes Mellitus, Shanghai, China
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level of FT3 within the reference range was positively related to BMI and waist circumference ( 5 , 6 ). Non-alcoholic fatty liver disease (NAFLD) is one of the most common complications of obesity. In recent years, some studies found that a high level
Julia Otten
Julia Otten
Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
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Andreas Stomby
Andreas Stomby
Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
Region Jönköping County, Jönköping, Sweden
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Region Jönköping County, Jönköping, Sweden
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Maria Waling
Maria Waling
Department of Food, Nutrition and Culinary Science, Umeå University, Umeå, Sweden
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Elin Chorell
Elin Chorell
Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
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Mats Ryberg
Mats Ryberg
Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
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Michael Svensson
Michael Svensson
Department of Community Medicine and Rehabilitation, Section for Sports Medicine, Umeå University, Umeå Sweden
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Jens Juul Holst
Jens Juul Holst
NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
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Tommy Olsson
Tommy Olsson
Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
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. Already at the study start, hepatic insulin sensitivity was associated with postprandial glucagon levels. Thus, postprandial glucagon secretion seems to be tightly related to hepatic insulin sensitivity ( 30 ). Nonalcoholic fatty liver disease has been
Katica Bajuk Studen
Katica Bajuk Studen
Nuclear Medicine Department, University Medical Centre Ljubljana, Ljubljana, Slovenia
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Marija Pfeifer
Marija Pfeifer
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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retrospective longitudinal cohort study in the United Kingdom evaluating nonalcoholic fatty liver disease (NAFLD) rates in 63,120 women with PCOS and 121,064 age-, BMI- and location-matched control women found that women with PCOS have an increased rate of NAFLD
Christine Rode Andreasen
Christine Rode Andreasen
Steno Diabetes Center Copenhagen, Gentofte, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Andreas Andersen
Andreas Andersen
Steno Diabetes Center Copenhagen, Gentofte, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Filip Krag Knop
Filip Krag Knop
Steno Diabetes Center Copenhagen, Gentofte, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Tina Vilsbøll
Tina Vilsbøll
Steno Diabetes Center Copenhagen, Gentofte, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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diseases Non-alcoholic fatty liver disease (NAFLD) including non-alcoholic steatohepatitis (NASH) is highly prevalent in patients with T2D and/or obesity. Currently, there are no FDA-approved treatments for NASH. In a recent phase II trial, patients with
