Caishun Zhang
Caishun Zhang
Special Medicine Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Junhua Yuan
Junhua Yuan
Special Medicine Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Qian Lin
Qian Lin
Special Medicine Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Manwen Li
Manwen Li
Special Medicine Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Liuxin Wang
Liuxin Wang
Hyperbaric Oxygen Therapy Department, Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China
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Rui Wang
Rui Wang
Special Medicine Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Xi Chen
Xi Chen
Physiology Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Zhengyao Jiang
Zhengyao Jiang
Physiology Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Kun Zhu
Kun Zhu
Intensive Care Unit Department, Affiliated Hospital of Qingdao University, Qingdao, China
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Xiaoli Chang
Xiaoli Chang
Institute of Acupuncture, Shandong University of Traditional Chinese Medicine, Jinan, China
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Bin Wang
Bin Wang
Special Medicine Department, College of Basic Medicine, Qingdao University, Qingdao, China
Medical Microbiology Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Medical Microbiology Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Jing Dong
Jing Dong
Special Medicine Department, College of Basic Medicine, Qingdao University, Qingdao, China
Physiology Department, College of Basic Medicine, Qingdao University, Qingdao, China
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Physiology Department, College of Basic Medicine, Qingdao University, Qingdao, China
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intake, body weight and enhance uncoupling protein1 (UCP-1) expression in brown adipose tissue (BAT) ( 20 ). However, the acute and chronic effects and mechanisms of ghrelin in the LPBN on feeding behavior and energy expenditure are yet to be elucidated
Xingrong Tan
Xingrong Tan
Department of Endocrinology, 9th People’s Hospital of Chongqing, Beibei City, Chongqong, China
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Wenjing Hu
Wenjing Hu
Chongqing Prevention and Treatment Hospital for Occupational Diseases, Chongqing, China
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Shan Yang
Shan Yang
Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China
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Han Dai
Han Dai
Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China
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Shangcheng Xu
Shangcheng Xu
Chongqing Prevention and Treatment Hospital for Occupational Diseases, Chongqing, China
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Gangyi Yang
Gangyi Yang
Department of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China
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Ling Li
Ling Li
Department of Endocrinology, 9th People’s Hospital of Chongqing, Beibei City, Chongqong, China
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Shiguo Tang
Shiguo Tang
Department of Endocrinology, 9th People’s Hospital of Chongqing, Beibei City, Chongqong, China
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Yi Wang
Yi Wang
Department of Endocrinology, 9th People’s Hospital of Chongqing, Beibei City, Chongqong, China
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pressure . Hypertension Research 2015 38 244 – 251 . ( https://doi.org/10.1038/hr.2014.165 ) 36 Elattar S Dimri M Satyanarayana A The tumor secretory factor ZAG promotes white adipose tissue browning and energy wasting . FASEB Journal 2018
Pernille Bækgaard Udesen
Pernille Bækgaard Udesen
The Fertility Clinic, Department of Gynecology and Obstetrics, Zealand University Hospital, Køge, Denmark
Department of Science and Environment, Roskilde University, Roskilde, Denmark
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Department of Science and Environment, Roskilde University, Roskilde, Denmark
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Dorte Glintborg
Dorte Glintborg
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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Anja Elaine Sørensen
Anja Elaine Sørensen
Department of Science and Environment, Roskilde University, Roskilde, Denmark
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Rikke Svendsen
Rikke Svendsen
Department of Science and Environment, Roskilde University, Roskilde, Denmark
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Nanna Louise Skov Nielsen
Nanna Louise Skov Nielsen
Department of Science and Environment, Roskilde University, Roskilde, Denmark
Department of Clinical Immunology, Næstved Hospital, Næstved, Denmark
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Department of Clinical Immunology, Næstved Hospital, Næstved, Denmark
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Marie Louise Muff Wissing
Marie Louise Muff Wissing
Aleris Hamlet Hospital Group, The Fertility Clinic, Søborg, Denmark
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Marianne Skovsager Andersen
Marianne Skovsager Andersen
Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark
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Anne Lis Mikkelsen Englund
Anne Lis Mikkelsen Englund
The Fertility Clinic, Department of Gynecology and Obstetrics, Zealand University Hospital, Køge, Denmark
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Louise Torp Dalgaard
Louise Torp Dalgaard
Department of Science and Environment, Roskilde University, Roskilde, Denmark
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-sensitive tissues of obese patients ( 10 , 11 ) and in patients with T2D ( 12 , 13 , 14 ). The role of miRNAs in metabolism and diabetes is quite complex ( 15 ) and involves many different tissues for example, liver, beta-cells, white and brown adipose tissue, as
David P Sonne
David P Sonne
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Asger Lund
Asger Lund
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Jens Faber
Jens Faber
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Jens J Holst
Jens J Holst
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Tina Vilsbøll
Tina Vilsbøll
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Filip K Knop
Filip K Knop
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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Department of Medicine, Department of Biomedical Sciences, Department of Endocrinology, Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, DK-2900 Hellerup, Denmark
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-coupled receptor TGR5 (2, 3, 4) . A study by Watanabe et al . (4) carried out in mice showed that cholic acid supplementation augmented energy expenditure in brown adipose tissue, caused weight reduction and improved insulin sensitivity. The effects were
Karim Gariani
Karim Gariani
Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals and Geneva University, Geneva, Switzerland
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François R Jornayvaz
François R Jornayvaz
Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals and Geneva University, Geneva, Switzerland
Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland
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lipogenesis and adipose tissue lipolysis, leading to an increased flux of fatty acids to the liver ( 30 ). Insulin resistance will also lead to adipose tissue dysfunction inducing secretion of inflammatory cytokines ( 31 ). Intrahepatic accumulation of fatty
Sebastião Freitas de Medeiros
Sebastião Freitas de Medeiros
Department of Gynecology and Obstetrics, Medical School, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Cinthia Marenza Ormond
Cinthia Marenza Ormond
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Matheus Antônio Souto de Medeiros
Matheus Antônio Souto de Medeiros
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Nayara de Souza Santos
Nayara de Souza Santos
Department of Gynecology and Obstetrics, Medical School, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Camila Regis Banhara
Camila Regis Banhara
Department of Gynecology and Obstetrics, Medical School, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Márcia Marly Winck Yamamoto
Márcia Marly Winck Yamamoto
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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( 36 ). Furthermore, the adipose tissue product leptin may also inhibit 3β-HSD II activity and increase 17-OHPE levels ( 37 , 38 ). The positive correlation between 17-OHPE and markers of dysglycemia found in the present study is in agreement with the
Melony C Fortuin-de Smidt
Melony C Fortuin-de Smidt
Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa
Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa
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Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa
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Amy E Mendham
Amy E Mendham
Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa
Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa
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Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa
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Jon Hauksson
Jon Hauksson
Department of Radiation Sciences, Radiation Physics and Biomedical Engineering, Umea University, Umea, Sweden
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Ali Alhamud
Ali Alhamud
Department of Human Biology, MRC/UCT Medical Imaging Research Unit, University of Cape Town, Cape Town, South Africa
The Modern Pioneer Center and ArSMRM for MRI Training and Development, Tripoli, Libya
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The Modern Pioneer Center and ArSMRM for MRI Training and Development, Tripoli, Libya
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Darko Stefanovski
Darko Stefanovski
Department of Clinical Studies, New Bolton Centre, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania, USA
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Olah Hakim
Olah Hakim
Department of Diabetes, Faculty of Life Sciences and Medicine, School of Life Course Sciences, King’s College London, London, UK
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Jeroen Swart
Jeroen Swart
Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa
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Louise M Goff
Louise M Goff
Department of Diabetes, Faculty of Life Sciences and Medicine, School of Life Course Sciences, King’s College London, London, UK
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Steven E Kahn
Steven E Kahn
Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, Veterans Affairs Puget Sound Health Care System, University of Washington, Seattle, Washington, USA
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Tommy Olsson
Tommy Olsson
Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden
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Julia H Goedecke
Julia H Goedecke
Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa
Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa
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Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa
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, muscle and adipose tissue, amongst others. However, the association of peripheral insulin clearance (CLp) with β-cell function needs further clarification. Few studies have assessed associations between measures of β-cell function and VAT ( 7 , 8 , 9
Huguette S Brink
Huguette S Brink
Department of Endocrinology, Maasstad Hospital, Rotterdam, The Netherlands
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Aart Jan van der Lely
Aart Jan van der Lely
Department of Endocrinology, Erasmus University MC, Rotterdam, The Netherlands
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Joke van der Linden
Joke van der Linden
Department of Endocrinology, Maasstad Hospital, Rotterdam, The Netherlands
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). Further prospective studies are required to investigate the predictive value of TNF& in GD, adjusting for measures of adiposity. High-sensitivity C-reactive protein (hsCRP) hsCRP is an acute-phase protein and is produced in response to tissue
Liselot Koelman
Liselot Koelman
Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany
Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
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Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
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Robin Reichmann
Robin Reichmann
Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
Department of Epidemiological Methods and Etiological Research, Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany
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Department of Epidemiological Methods and Etiological Research, Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany
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Claudia Börnhorst
Claudia Börnhorst
Department of Biometry and Data Management, Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany
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Matthias B Schulze
Matthias B Schulze
Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany
Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
German Center for Diabetes Research (DZD), Neuherberg, Germany
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Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
German Center for Diabetes Research (DZD), Neuherberg, Germany
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Cornelia Weikert
Cornelia Weikert
Department of Food Safety, German Federal Institute for Risk Assessment, Berlin, Germany
Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany
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Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany
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Ronald Biemann
Ronald Biemann
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany
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Berend Isermann
Berend Isermann
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany
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Andreas Fritsche
Andreas Fritsche
Division of Endocrinology, Diabetology, Nephrology, Vascular Disease and Clinical Chemistry, Department of Internal Medicine, University of Tübingen, Tübingen, Germany
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Krasimira Aleksandrova
Krasimira Aleksandrova
Department of Epidemiological Methods and Etiological Research, Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany
Faculty of Human and Health Sciences, University of Bremen, Bremen, Germany
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Faculty of Human and Health Sciences, University of Bremen, Bremen, Germany
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other inflammation markers such as CRP as shown in our data. However, CRP is a non-specific biomarker of inflammation and may also reflect obesity-associated inflammatory phenotype. Indeed, the enlarged adipose tissue is one important source of secretion
Valeria Hirschler
Valeria Hirschler
University of Buenos Aires, Buenos Aires, Argentina
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Claudia Molinari
Claudia Molinari
University of Buenos Aires, Buenos Aires, Argentina
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Silvia Lapertosa
Silvia Lapertosa
UNNE, Corrientes, Argentina
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Gustavo Maccallini
Gustavo Maccallini
Hidalgo Laboratories, Buenos Aires, Argentina
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Claudio D Gonzalez
Claudio D Gonzalez
CEMIC, Buenos Aires, Argentina
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with high secretory adipose tissue or increased responsiveness to the effects of adipokines ( 16 ). A review proposed that excess caloric intake leads to an increase in body fat. The expansion ability of the s.c. fat tissue determines the lipid
