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Introduction Fanconi anemia (FA), dyskeratosis congenita (DC), and Diamond–Blackfan anemia (DBA) are inherited bone marrow failure syndromes (IBMFS) associated with high risks of bone marrow failure (BMF), myelodysplastic syndrome, leukemia
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-induced decline in bone formation is associated with an increased fracture risk related both to the dose and duration of GC treatment ( 2 ). Recent studies on bone mineral density (BMD) in PAI and CAH patients showed different results. This may be not only due to
Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK
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Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK
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importance of cancer treatment late effects and survivorship is being increasingly recognised. Bone toxicity, and more specifically radiotherapy-related insufficiency fractures (RRIFs), are well-established late effects of pelvic radiotherapy, with
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Jan van Goyen Medical Center, Department of Internal Medicine, Amsterdam, the Netherlands
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Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
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Introduction Pregnancy and lactation are challenging situations for the mother’s skeletal homeostasis. Significant changes in maternal calcium and bone metabolism must occur to fulfill the calcium requirements to build the fetal skeleton
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Introduction X-linked hypophosphataemia (XLH) is a rare genetic condition affecting phosphate homeostasis, which results in debilitating bone deformation from an early age with lifelong consequences. The condition is caused by a pathogenic
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Department of Clinical Research Center, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China
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Introduction Osteoporosis, characterized by a reduced bone mass and deterioration in the microarchitecture of bone ( 1 ), is a growing concern in aging societies ( 2 ). Osteoporosis is diagnosed using bone mineral density (BMD) measurements
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Department of Clinical Nutrition, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
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GA Steven MS Hosking DJ . Correction of vitamin D deficiency in elderly long-stay patients by sunlight exposure . Bone 1990 12 296 – 297 . 14 Hirani V Primatesta P . Vitamin D concentrations among people aged 65 years and over living in
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Department of Endocrinology, Diabetes and Metabolic diseases, Elias Hospital, Bucharest, Romania
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involvement, have been proposed. IBD is associated with decreased bone mineral density (BMD), with the prevalence of osteoporosis and osteopenia reported to be between 22 and 77%, depending on the study ( 1 ). Sheth et al. found that the prevalence of
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). Earlier studies on effects of HT in trans people focused on bone mineral density (BMD) and body composition. These studies found an increase in lean body mass in transmen and a decrease in lean body mass in transwomen ( 4 , 5 ). BMD increased in both
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Introduction Osteoporosis is a metabolic bone disease characterized by decreased bone mineral density (BMD) and perturbation of bone quality. World Health Organization (WHO) guidelines use dual-energy X-ray absorptiometry (DXA) scans to