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,554,830 people aged ≥ 40 years with T2DM underwent a health examination. Patients who had at least one service claim with a diagnosis of T2DM based on ICD-10 (E11–E14) and patients prescribed at least one antidiabetic drug at any time over 1 year were classified
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Department of Endocrinology and Metabolism, Peking University People’s Hospital, Beijing, China
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Chinese with T2DM ( 6 ). Participants with the following conditions were enrolled: (1) aged 50 years or older with a diagnosis of T2DM and at least one of the following risk factors: history of cardiovascular disease or cerebrovascular disease
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University Hospital, Krakow, Poland
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University Hospital, Krakow, Poland
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University Hospital, Krakow, Poland
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University Hospital, Krakow, Poland
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pathways and the analysis was performed by Q-PCR methods. Recently, we conducted an analysis in which we characterized transcriptome wide gene expression profile using Illumina microarrays in patients with type 2 diabetes (T2DM) and DFU in comparison with
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Background:
Evidence has demonstrated that visceral fat area (VFA) and subcutaneous fat area (SFA) had different influences on cardiovascular disease (CVD) risk in patients with type 2 diabetes mellitus (T2DM). We aimed to investigate the relationship between the visceral fat area (VFA) to subcutaneous fat area (SFA) ratio (V/S) and carotid atherosclerosis (CAS) in patients with T2DM.
Methods:
From January 2018 to May 2023, 1,838 patients with T2DM admitted to the National Metabolic Management Centre in our hospital were assigned to two groups based on comorbid CAS. Dual bioelectrical impedance analysis was used to measure the VAF and SFA, and the V/S was calculated. Patient characteristics and serum biochemical indices were compared between groups. Factors influencing comorbid CAS were determined, and correlations between V/S and other clinical indices were analyzed.
Results:
The group with comorbid CAS included 858 individuals and 980 without comorbid CAS. Those with comorbid CAS were older and had a longer disease duration, more significant systolic blood pressure, and greater V/S. The proportions of patients with comorbid hypertension increased significantly with the V/S ratio. The V/S ratio positively correlated with triglyceride (TG), low-density lipoprotein cholesterol levels, and waist circumference. According to binary logistic regression analysis, V/S was an independent risk factor for CAS.
Conclusion:
Elevated V/S is an independent risk factor for CAS in patients with T2DM.
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, HbA1c levels of 6.5–9.0%, and 45–75 years old. The control group consisted of patients without T2DM and with no clinical CVD. The patients with diabetes and the controls were selected from a larger population-based study (Strazhesko ID, Tkacheva ON
Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fujian Province University, Fuzhou, Fujian Province, China
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Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fujian Province University, Fuzhou, Fujian Province, China
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Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fujian Province University, Fuzhou, Fujian Province, China
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Introduction Type 2 diabetes mellitus (T2DM) is considered as a metabolic disease with hyperglycemia and vascular and/or nervous complications. In China, the reported prevalence of T2DM is 11.6% ( 1 ), which appears to have increased in the
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Introduction Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes mellitus (T2DM), but the adverse metabolic consequences of obesity vary between individuals (1) . The mechanisms underlying obesity
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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and the scheduled radiotherapy. Endpoints The primary endpoint was DM defined as two random plasma glucose measurements ≥11.1 mmol/L. The WHO diagnostic criteria for DM are fasting plasma glucose ≥7.0 mmol/L or 2-h plasma glucose ≥11.1 mmol
Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China
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(35.5 million, aged ≥60 years) ( 2 ). Impaired glucose tolerance (IGT) is a marked risk factor for T2DM, with an estimated 374 million people aged 18–99 years having IGT in 2017, and approximately half of these adults were above the age of 50 years ( 1
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Introduction Diabetes is a public health issue, and there are over 0.4 billion people suffering from diabetes over the world, and its prevalence is still increasing remarkably every year ( 1 ). Type 2 diabetes mellitus (T2DM) is the major type
