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-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment-insulin resistance; IR, insulin resistance; LH, luteinizing hormone; OR, odds ratio; PCOS, polycystic ovary syndrome; SHBG, sex hormone-binding globulin. Since insulin resistance is a
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oscillometric monitor, following standards of BP measurements. Serum biochemical measurements (glucose, insulin, sex hormone-binding globulin (SHBG)) and serum hormone levels (follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), T
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formation. More evidence for the important role of estrogens in bone health of older men comes from several large studies showing that low levels of E2 and high levels of sex hormone-binding globulin (SHBG) are associated with reduced BMD, the occurrence of
Department of Endocrinology, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
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Medical Clinic, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
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Department of Gastroenterology, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
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K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Trondheim, Norway
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Medical Clinic, Trondheim University Hospital (St Olavs Hospital), Trondheim, Norway
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-terminal propeptide type 1 collagen; PTH, parathyroid hormone; SHBG, sex hormone-binding globulin. Bone mineral density, trabecular bone score and bone material strength index Men with T1D exhibited lower Z-scores than controls at all sites but was
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Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK
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as a marker of peripheral dihydrotestosterone production, but we have not attempted this. Mitotane increases hepatic production of sex hormone binding globulin (SHBG) (23) , so this may be another factor. Trial of the androgen analogue, nandrolone
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tube RIA (DiaSorin S. p. A., Salluggia, Italy and Diagnostic Products Corporation, Los Angeles, CA, USA, respectively). Within and between assays, coefficients of variation for testosterone were 1.05 and 5.75%. Sex hormone-binding globulin (SHBG
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Growth and Reproduction. Serum levels of FSH, LH, sex hormone-binding globulin (SHBG), testosterone and estradiol were measured by time-resolved immunofluorometric assays (Delfia, PerkinElmer). Intra-assay and interassay CVs for FSH and LH were 3 and 5
Department of Diabetes and Endocrinology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, UK
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The Leicester Biomedical Research Centre, Leicester and Loughborough, UK
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.3) Sex Hormone Binding Globulin (mmol/L) 47.0 (40.3) 56.9 (48.4) Free Androgen Index (%) 6.5 (6.0) 6.8 (5.4) Physical activity Steps (counts/day) 6294 (4785–8478) 6353 (5147–7521) Light PA (min/day) 262.3 (226
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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concentration. Thus, the biological activity of circulating T depends on the concentration of total T, albumin and sex hormone-binding globulin (SHBG), the transendothelial transport to target tissues, as well as the peripheral conversion rate of T into
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, abnormal glucose disposal, relative postprandial hyperinsulinemia and increased hepatic fat content compared to normal-weight controls were reported ( 37 ). PCOS patients often have lower sex-hormone-binding globulin (SHBG) levels, which could be further