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, locally advanced or metastatic PPGL, symptomatic or progressive disease is usually treated with chemotherapy, radionuclide therapy ( 131 I-metaiodobenzylguanidine ( 131 I-MIBG) and peptide receptor radionuclide therapy (PRRT)), external radiotherapy
Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Department of Radiology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center, Lundlaan, EA Utrecht, The Netherlands
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Effects of Childhood Cancer Guideline Harmonization Group (IGHG) recommends screening of bone problems in all CCS treated with cranial radiotherapy ( 2 ). For children with LGG, rarely treated with radiotherapy, there is no surveillance protocol for bone
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Green Templeton College, University of Oxford, Oxford, UK
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antigen; GFAP, glial fibrillary acid protein; IHC, immunohistochemistry; RT, radiotherapy; TSS, transsphenoidal surgery; TTF-1, thyroid transcription factor-1. Table 3 Comparative analysis of TTF-1 positive spindle cell oncocytomas (SCO) in
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suspicion of AI); - a history of radiotherapy (RT, at least 3 months before the suspicion of AI); - signs or symptoms consistent with AI: orthostatic hypotension (fall in systolic > 20 mmHg and diastolic > 10 mmHg within 3 min upon standing
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Amsterdam UMC, Emma’s Children’s Hospital, Amsterdam, The Netherlands
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radiotherapy exposure or high cumulative chemotherapy doses in newer treatment approaches, which are anticipated to be associated with improved life expectancy as a consequence of fewer, life-threatening late effects. However, despite these important adaptions
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and dacarbazine; EBRT, external beam radiotherapy; MIBG, metaiodobenzyl guanidine; PRRT, peptide receptor based radiotherapy. The baseline characteristics of benign and malignant PCC/PGL are summarised in Table 2 . In the benign group, 31
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unclear if this is due to GHD per se , or to confounding factors often found in acquired GHD (other pituitary hormone deficiencies, inadequate replacements and pituitary surgery or radiotherapy) (7, 8) . A model of isolated GHD (IGHD) would be preferable
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randomisation The baseline biopsy was obtained at least 1 month after radiotherapy, corresponding to 5months or more after initiation of ADT depending on the duration of the neo-adjuvant part of ADT. Thereafter, the ADT-treated PCa patients were randomly
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any patient with grade 2–3 disease, any patient with an advanced stage disease and any patient with heterologous elements ( 20 ). Radiotherapy is of unknown beneficial value. None of the patients in our study were subjected to chemo- or radiotherapy
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absence of metastatic disease on preoperative CT scan of chest and abdomen and complete resection during surgery (R0). Furthermore, data regarding treatment details of ACC were collected, including type of surgical approach, radiotherapy, chemotherapy and