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Guoquan Zhu, Yuying Deng, Liqin Pan, Wei Ouyang, Huijuan Feng, Juqing Wu, Pan Chen, Jing Wang, Yanying Chen and Jiaxin Luo

40%, especially in patients with intermediate to high recurrence risk ( 6 , 7 , 8 , 9 ). Therefore, identifying the specific features of PTC that correlate with tumor behavior and prognosis has become an important consideration in clinical

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Matilde Calanchini, Michael Tadman, Jesper Krogh, Andrea Fabbri, Ashley Grossman and Brian Shine

decrease the urinary 5-HIAA levels. Thus, we were unable to test the diagnostic sensitivity and specificity of spot urinary 5-HIAA per se and its utility in determining the prognosis and the severity of the CS. However, using the 24-h urinary 5-HIAA as

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Mubashir Mulla and Klaus-Martin Schulte

have concluded that in PTC with no other adverse features, the state of the CLNs does not influence prognosis (3) . Despite the high incidence of metastases, prophylactic CLN dissection has been discouraged because CLNM has not been considered to be a

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Sofia S Pereira, Tiago Morais, Madalena M Costa, Mariana P Monteiro and Duarte Pignatelli

prevalence of more than 4% in the adult population; in contrast, adrenocortical carcinomas (ACCs) are rare, having an incidence of between 0.5 and 2 per million, and are generally highly aggressive, with a poor prognosis that is expressed by a 5-year survival

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Linfei Yang, Xiao Yu and Yongchao Yang

presentation that depends on histological features and disease staging, resulting in widely variable prognoses for different pNENs ( 4 ). Therefore, there is a critical need to better define the molecular features associated with prognosis in these tumours

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Anne Jouinot, Bernard Royer, Etienne Chatelut, Sotheara Moeung, Guillaume Assié, Audrey Thomas-Schoemann, Jérôme Bertherat, François Goldwasser and Benoit Blanchet

Introduction Adrenocortical carcinoma (ACC) is a rare malignancy (1 per million each year) with a poor prognosis ( 1 ). Even after complete surgery, up to 70% of patients will develop recurrence ( 1 ). Medical treatments show limited efficacy

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Hugo R Ramos, Andreas L Birkenfeld and Adolfo J de Bold

–88 pg/ml). These findings posed the question as to why it is that in some patients the plasma levels of cardiac natriuretic peptides (cNP) are unexpectedly low, and what is their value in the prognosis for these patients? The cardiologist's perspective

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Agnieszka Bogusz, Svenja Boekhoff, Monika Warmuth-Metz, Gabriele Calaminus, Maria Eveslage and Hermann L Müller

anatomical proximity of CP to hypothalamic–pituitary axes ( 8 , 9 , 10 ). Improvements of prognosis in terms of QoL and progression-free survival (PFS) will only be achieved by multidisciplinary, risk-adapted neurosurgical and radiooncological treatment

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Flávia O Valentim, Bárbara P Coelho, Hélio A Miot, Caroline Y Hayashi, Danilo T A Jaune, Cristiano C Oliveira, Mariângela E A Marques, José Vicente Tagliarini, Emanuel C Castilho, Paula Soares and Gláucia M F S Mazeto

diagnosis and prognosis of neoplastic lesions ( 3 ). Computerized image analysis is an objective and highly reproducible tool in daily practice and has proven to be a promising resource for assessing thyroid lesions. More widely used for assessing

Open access

Alberto Bongiovanni, Federica Recine, Flavia Foca, Valentina Fausti, Nada Riva, Greta Fabbri, Stefano Severi, Chiara Liverani, Alessandro De Vita, Chiara Spadazzi, Giacomo Miserocchi, Laura Mercatali, Dino Amadori and Toni Ibrahim

benefits and side effects, as well as life expectancy, differ from those of their younger counterparts ( 16 ). For these reasons, little information is available on prognosis and on the risks of treatment in this subgroup, especially for those with NEN