Filter

Refine by collections

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 41 - 50 of 379 items for :

Clear All
Qinglei Yin Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Guangdong Geriatric Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China

Search for other papers by Qinglei Yin in
Google Scholar
PubMed Close
,
Zhou Jin Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Zhou Jin in
Google Scholar
PubMed Close
,
Yulin Zhou Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Yulin Zhou in
Google Scholar
PubMed Close
,
Dalong Song Guangdong Geriatric Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
Reproductive Medicine Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China

Search for other papers by Dalong Song in
Google Scholar
PubMed Close
,
Chenyang Fu Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Chenyang Fu in
Google Scholar
PubMed Close
,
FengJiao Huang Reproductive Medicine Center, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
Division of Endocrinology, Department of Internal Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

Search for other papers by FengJiao Huang in
Google Scholar
PubMed Close
, and
Shu Wang Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Shu Wang in
Google Scholar
PubMed Close

environmental factors trigger the occurrence of GD under genetical background, however, the pathogenesis is still incompletely understood ( 2 ). Advances in cellular immunology have opened a new era of or new insights into exploring the mechanisms of immune

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0373
Volume/Issue:
Volume 9: Issue 12
Open access
Hichem Bouguerra Université Tunis El-Manar, Faculté des Sciences de Tunis, Laboratoire de Génétique, Immunologie et pathologies Humaines, Tunis, Tunisie
Université Côte d'Azur, INSERM, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France

Search for other papers by Hichem Bouguerra in
Google Scholar
PubMed Close
,
Gorrab Amal Université Tunis El-Manar, Faculté des Sciences de Tunis, Laboratoire de Génétique, Immunologie et pathologies Humaines, Tunis, Tunisie

Search for other papers by Gorrab Amal in
Google Scholar
PubMed Close
,
Stephan Clavel Université Côte d'Azur, INSERM, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France

Search for other papers by Stephan Clavel in
Google Scholar
PubMed Close
,
Hamouda Boussen Département d’Oncologie Médicale, Hôpital Abderrahman Mami, Ariana, Tunisia

Search for other papers by Hamouda Boussen in
Google Scholar
PubMed Close
,
Jean-François Louet Université Côte d'Azur, INSERM, C3M, Team Cellular and Molecular Physiopathology of Obesity and Diabetes, Nice, France

Search for other papers by Jean-François Louet in
Google Scholar
PubMed Close
, and
Asma Gati Université Tunis El-Manar, Faculté des Sciences de Tunis, Laboratoire de Génétique, Immunologie et pathologies Humaines, Tunis, Tunisie

Search for other papers by Asma Gati in
Google Scholar
PubMed Close

/ERK 1/2, PI-3K/AKT) and non-canonical signaling pathways (JNK, p38 MAPK, PKC and AMPK), which promote proliferation, migration, and angiogenesis in BC ( 7 ). Yet, few studies have investigated the involvement of leptin on tumor/immune cells conflict. The

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0109
Volume/Issue:
Volume 9: Issue 6
Open access
Zhaoxiang Liu Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Zhaoxiang Liu in
Google Scholar
PubMed Close
,
Mingqiang Zhang Department of Respiratory and Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Mingqiang Zhang in
Google Scholar
PubMed Close
,
Xiaohu Shi Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China

Search for other papers by Xiaohu Shi in
Google Scholar
PubMed Close
,
Wenhui Zhao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Wenhui Zhao in
Google Scholar
PubMed Close
,
Chenxiang Cao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Chenxiang Cao in
Google Scholar
PubMed Close
,
Lixia Jin Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Lixia Jin in
Google Scholar
PubMed Close
,
Yanlei Wang Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Yanlei Wang in
Google Scholar
PubMed Close
, and
Jianzhong Xiao Department of Endocrinology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China

Search for other papers by Jianzhong Xiao in
Google Scholar
PubMed Close

-grade inflammatory disease characterized by increased circulating concentrations of inflammatory cytokines and the recruitment of immune cells, including macrophages and T cells, to metabolic tissues ( 2 ). Myeloid-derived suppressor cells (MDSCs) represent a group

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0218
Volume/Issue:
Volume 12: Issue 9
Open access
Wentao Zhou The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China
Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Wentao Zhou in
Google Scholar
PubMed Close
,
Tiantao Kuang The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Tiantao Kuang in
Google Scholar
PubMed Close
,
Xu Han Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Xu Han in
Google Scholar
PubMed Close
,
Wenqi Chen Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Wenqi Chen in
Google Scholar
PubMed Close
,
Xuefeng Xu The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Xuefeng Xu in
Google Scholar
PubMed Close
,
Wenhui Lou Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Wenhui Lou in
Google Scholar
PubMed Close
, and
Dansong Wang The Research Institution of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Dansong Wang in
Google Scholar
PubMed Close

-to-monocyte (LMR), systemic immune-inflammation (SII) index, NLR, PLR and the counts of lymphocyte, monocyte and neutrophil for prognosis among all curatively resected pNEN patients, the first two of which were rarely paid attention to in the previous research. As

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0541
Volume/Issue:
Volume 9: Issue 4
Open access
Maria Angela D'amico Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy

Search for other papers by Maria Angela D'amico in
Google Scholar
PubMed Close
,
Barbara Ghinassi Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy

Search for other papers by Barbara Ghinassi in
Google Scholar
PubMed Close
,
Pascal Izzicupo Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy

Search for other papers by Pascal Izzicupo in
Google Scholar
PubMed Close
,
Lamberto Manzoli Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy

Search for other papers by Lamberto Manzoli in
Google Scholar
PubMed Close
, and
A Di Baldassarre Section of Human Morphology, Department of Medicine and Aging Sciences, G. d'Annunzio University of Chieti–Pescara, Via Dei Vestini 31, 66013 Chieti, Italy

Search for other papers by A Di Baldassarre in
Google Scholar
PubMed Close

several bioactive fragments, which exert a broad spectrum of regulatory activities by influencing the endocrine, the cardiovascular, and the immune systems and by affecting the glucose or calcium homeostasis ( Fig. 2 A) (20) . Some peptides exert similar

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-14-0027
Volume/Issue:
Volume 3: Issue 2
Open access
Jens F Rehfeld Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Jens F Rehfeld in
Google Scholar
PubMed Close

 Atrial myocytes 10  Ventricular myocytes 2 Mononuclear immune cells b ++ a Orders of magnitude based on measurement of tissue extracts from different mammalian species. b Expression determined only by immunocytochemistry

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-21-0025
Volume/Issue:
Volume 10: Issue 3
Open access
Wenrui Wang Department of Endocrinology, The Second Hospital of Jilin University, Changchun, People’s Republic of China

Search for other papers by Wenrui Wang in
Google Scholar
PubMed Close
and
Chuan Zhang Department of Endocrinology, The Second Hospital of Jilin University, Changchun, People’s Republic of China

Search for other papers by Chuan Zhang in
Google Scholar
PubMed Close

carries risks of hypoglycemic episodes, weight gain, and an increased incidence of cancer ( 5 ). The effectiveness of islet transplantation is limited by a shortage of donor islets and immune rejection ( 6 ). Therefore, new therapeutic strategies are

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-21-0260
Volume/Issue:
Volume 10: Issue 8
Open access
Tiina Vesterinen HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland

Search for other papers by Tiina Vesterinen in
Google Scholar
PubMed Close
,
Teijo Kuopio Department of Biological and Environmental Science, University of Jyväskylä and Department of Pathology, Central Finland Health Care District, Jyväskylä, Finland

Search for other papers by Teijo Kuopio in
Google Scholar
PubMed Close
,
Maarit Ahtiainen Department of Education and Research, Central Finland Central Hospital, Jyväskylä, Finland

Search for other papers by Maarit Ahtiainen in
Google Scholar
PubMed Close
,
Aija Knuuttila Department of Pulmonary Medicine, Heart and Lung Center, and Cancer Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

Search for other papers by Aija Knuuttila in
Google Scholar
PubMed Close
,
Harri Mustonen Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

Search for other papers by Harri Mustonen in
Google Scholar
PubMed Close
,
Kaisa Salmenkivi HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

Search for other papers by Kaisa Salmenkivi in
Google Scholar
PubMed Close
,
Johanna Arola HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

Search for other papers by Johanna Arola in
Google Scholar
PubMed Close
, and
Caj Haglund Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland

Search for other papers by Caj Haglund in
Google Scholar
PubMed Close

). Over recent decades, several studies have shown that the immune system plays a critical role in recognizing and eliminating malignant cells. In particular, elevated levels of cytotoxic CD8 + T cells in the tumor microenvironment have been linked to a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0308
Volume/Issue:
Volume 8: Issue 8
Open access
Trevor Lewis Physiotherapy Department, Aintree University Hospital NHS Foundation Trust, Liverpool, UK

Search for other papers by Trevor Lewis in
Google Scholar
PubMed Close
,
Eva Zeisig Department of Surgical and Perioperative Sciences, Umeå Univerisity, Umeå, Sweden

Search for other papers by Eva Zeisig in
Google Scholar
PubMed Close
, and
Jamie E Gaida University of Canberra Research Institute for Sport and Exercise (UCRISE), Canberra, Australian Capital Territory, Australia

Search for other papers by Jamie E Gaida in
Google Scholar
PubMed Close

). Glucocorticoid hormones regulate an array of physiologic processes including energy homeostasis, inflammatory and immune responses, cardiovascular function, reproduction, and cognition ( 13 , 15 ). While glucocorticoid function has been extensively studied in

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-19-0555
Volume/Issue:
Volume 9: Issue 3
Open access
Erik Rösner Institute of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany

Search for other papers by Erik Rösner in
Google Scholar
PubMed Close
,
Daniel Kaemmerer Department of General and Visceral Surgery, Zentralklinik Bad Berka, Bad Berka, Germany

Search for other papers by Daniel Kaemmerer in
Google Scholar
PubMed Close
,
Elisa Neubauer Institute of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany

Search for other papers by Elisa Neubauer in
Google Scholar
PubMed Close
,
Jörg Sänger Laboratory of Pathology and Cytology Bad Berka, Bad Berka, Germany

Search for other papers by Jörg Sänger in
Google Scholar
PubMed Close
, and
Amelie Lupp Institute of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany

Search for other papers by Amelie Lupp in
Google Scholar
PubMed Close

a downregulation of T-cell activation. Meanwhile, PD-L1 is often overexpressed in neoplastic tissues, where it promotes tumour evasion of the immune system ( 5 , 6 , 7 ). Several anti-PD-1 and anti-PD-L1 antibodies have been developed, such as

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0540
Volume/Issue:
Volume 10: Issue 2
Open access