St Michael's Hospital, Metabolism Laboratory, School of Medicine and Medical Sciences, Dún Laoghaire, Dublin, Ireland
St Michael's Hospital, Metabolism Laboratory, School of Medicine and Medical Sciences, Dún Laoghaire, Dublin, Ireland
Search for other papers by Malachi J McKenna in
Google Scholar
PubMed
Search for other papers by Barbara F Murray in
Google Scholar
PubMed
-dose oral vitamin D that had falls and fractures as outcome measures, intervention resulted in increased risk of falls and fractures; in a small sample of the treated group, 25OHD levels reached an average concentration of 120 nmol/l that approximates the
Department of Endocrinology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Search for other papers by Lizhi Zhang in
Google Scholar
PubMed
Search for other papers by Jinwei He in
Google Scholar
PubMed
Search for other papers by Xiang Sun in
Google Scholar
PubMed
Search for other papers by Dongyue Pang in
Google Scholar
PubMed
Search for other papers by Jingjing Hu in
Google Scholar
PubMed
Search for other papers by Bo Feng in
Google Scholar
PubMed
884 postmenopausal women was 47.41 years, and 90% of them had osteopenia/osteoporosis and 307 women had a history of fractures. These 307 women were ruled out of diseases and external factors that affect bone metabolism, accounting for approximately 34
Search for other papers by Jiaxin Luo in
Google Scholar
PubMed
Search for other papers by Weili Yin in
Google Scholar
PubMed
Search for other papers by Qiuxia Lin in
Google Scholar
PubMed
Search for other papers by Juqing Wu in
Google Scholar
PubMed
Search for other papers by Pan Chen in
Google Scholar
PubMed
Search for other papers by Yuanna Ling in
Google Scholar
PubMed
Search for other papers by Jing Wang in
Google Scholar
PubMed
Search for other papers by Zhen Li in
Google Scholar
PubMed
Search for other papers by Liqin Pan in
Google Scholar
PubMed
Search for other papers by Yanying Chen in
Google Scholar
PubMed
Search for other papers by Wei Ouyang in
Google Scholar
PubMed
Search for other papers by Huijuan Feng in
Google Scholar
PubMed
soft tissue components; (ii) new SREs (pathological fractures, cord compression, surgery, or EBRT) ( 13 ); (iii) Also, when a bone lesion was measurable (with a soft tissue mass ≥10 mm), an increase of at least 20% (with at least a 5-mm increase) in the
F.I.R.M.O. Italian Foundation for the Research on Bone Diseases, Florence, Italy
Search for other papers by Francesca Marini in
Google Scholar
PubMed
Search for other papers by Francesca Giusti in
Google Scholar
PubMed
Search for other papers by Teresa Iantomasi in
Google Scholar
PubMed
Search for other papers by Federica Cioppi in
Google Scholar
PubMed
Search for other papers by Maria Luisa Brandi in
Google Scholar
PubMed
alteration of the degree of osteoclast–osteoblast coupling, resulting in bone mineral density (BMD) loss ( 9 ). ACTH-secreting adenomas cause Cushing syndrome, of which osteoporosis and increased risk of fragility fracture are well-recognized complications
Search for other papers by Stefan Pilz in
Google Scholar
PubMed
Search for other papers by Armin Zittermann in
Google Scholar
PubMed
Search for other papers by Christian Trummer in
Google Scholar
PubMed
Search for other papers by Verena Theiler-Schwetz in
Google Scholar
PubMed
Search for other papers by Elisabeth Lerchbaum in
Google Scholar
PubMed
Search for other papers by Martin H Keppel in
Google Scholar
PubMed
Search for other papers by Martin R Grübler in
Google Scholar
PubMed
Medical Clinic V (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Ruperto-Carola University of Heidelberg, Heidelberg, Germany
Synlab Medical Center of Human Genetics Mannheim, Mannheim, Germany
Search for other papers by Winfried März in
Google Scholar
PubMed
Search for other papers by Marlene Pandis in
Google Scholar
PubMed
supplementation on falls and fractures, the current meta-analyses of RCTs draw inconsistent conclusions with either a neutral or a small beneficial effect ( 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 ). Beyond methodological issues of
Search for other papers by Kaisu Luiro in
Google Scholar
PubMed
Search for other papers by Kristiina Aittomäki in
Google Scholar
PubMed
Search for other papers by Pekka Jousilahti in
Google Scholar
PubMed
Department of Obstetrics and Gynecology, University of Oulu and Oulu University Hospital, Medical Research Center, PEDEGO Research Unit, Oulu, Finland
Search for other papers by Juha S Tapanainen in
Google Scholar
PubMed
due to CVD, osteoporosis and fractures. In addition, impairment of cognitive functions, dementia, Parkinsonism, and reduced sexual function and psychological well-being have been reported ( 12 ). Most of the evidence comes from observational studies of
Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Search for other papers by Georgios Kontogeorgos in
Google Scholar
PubMed
Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Search for other papers by Zoi Mamasoula in
Google Scholar
PubMed
Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden
Search for other papers by Emily Krantz in
Google Scholar
PubMed
Section for Endocrinology, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Search for other papers by Penelope Trimpou in
Google Scholar
PubMed
Section for Endocrinology, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Search for other papers by Kerstin Landin-Wilhelmsen in
Google Scholar
PubMed
Endocrine Out-Patient Clinic, Carlanderska Hospital, Gothenburg, Sweden
Search for other papers by Christine M Laine in
Google Scholar
PubMed
doses, laboratory analyses, blood pressure, and the occurrence of other comorbidities and complications, such as renal failure and soft tissue calcifications, as well as fracture history were recorded. Patients were divided into two different groups
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Henrik Falhammar in
Google Scholar
PubMed
Search for other papers by Hedi Claahsen-van der Grinten in
Google Scholar
PubMed
Search for other papers by Nicole Reisch in
Google Scholar
PubMed
Search for other papers by Jolanta Slowikowska-Hilczer in
Google Scholar
PubMed
Department of Paediatric Endocrinology, Astrid Lindgren Children Hospital, Karolinska University Hospital, Stockholm, Sweden
Search for other papers by Anna Nordenström in
Google Scholar
PubMed
Search for other papers by Robert Roehle in
Google Scholar
PubMed
Department of Pediatric Endocrinology, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France
Search for other papers by Claire Bouvattier in
Google Scholar
PubMed
Search for other papers by Baudewijntje P C Kreukels in
Google Scholar
PubMed
Search for other papers by Birgit Köhler in
Google Scholar
PubMed
Search for other papers by on behalf of the dsd-LIFE group in
Google Scholar
PubMed
disorders in addition to decreased bone health with increased fracture incidence for all groups ( 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ). A healthy lifestyle can modify and prevent many of these
Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
Search for other papers by K Amrein in
Google Scholar
PubMed
Search for other papers by A Papinutti in
Google Scholar
PubMed
Department of General Surgery, St. Elisabeth’s Hospital, Graz, Austria
Search for other papers by E Mathew in
Google Scholar
PubMed
Search for other papers by G Vila in
Google Scholar
PubMed
Search for other papers by D Parekh in
Google Scholar
PubMed
) Bone Limited available data in ICU survivors suggest impaired bone health and high fracture risk ( 38 , 39 , 40 , 41 , 83 ). 1,25(OH)(2)D(3) is known primarily as a regulator of calcium, but it also controls phosphate (re)absorption at the
Search for other papers by Maria Mizamtsidi in
Google Scholar
PubMed
Search for other papers by Constantinos Nastos in
Google Scholar
PubMed
Search for other papers by George Mastorakos in
Google Scholar
PubMed
Search for other papers by Roberto Dina in
Google Scholar
PubMed
Search for other papers by Ioannis Vassiliou in
Google Scholar
PubMed
Search for other papers by Maria Gazouli in
Google Scholar
PubMed
Search for other papers by Fausto Palazzo in
Google Scholar
PubMed
/3 radius or low-energy fracture, glomerular filtration rate (GFR) of <60 mL/min, nephrocalcinosis, renal stones or high stone risk). Table 1 presents the latest guidelines in comparison with older ones for the management of asymptomatic pHPT. Data from