Department of Endocrinology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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884 postmenopausal women was 47.41 years, and 90% of them had osteopenia/osteoporosis and 307 women had a history of fractures. These 307 women were ruled out of diseases and external factors that affect bone metabolism, accounting for approximately 34
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soft tissue components; (ii) new SREs (pathological fractures, cord compression, surgery, or EBRT) ( 13 ); (iii) Also, when a bone lesion was measurable (with a soft tissue mass ≥10 mm), an increase of at least 20% (with at least a 5-mm increase) in the
F.I.R.M.O. Italian Foundation for the Research on Bone Diseases, Florence, Italy
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alteration of the degree of osteoclast–osteoblast coupling, resulting in bone mineral density (BMD) loss ( 9 ). ACTH-secreting adenomas cause Cushing syndrome, of which osteoporosis and increased risk of fragility fracture are well-recognized complications
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Medical Clinic V (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Ruperto-Carola University of Heidelberg, Heidelberg, Germany
Synlab Medical Center of Human Genetics Mannheim, Mannheim, Germany
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supplementation on falls and fractures, the current meta-analyses of RCTs draw inconsistent conclusions with either a neutral or a small beneficial effect ( 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 ). Beyond methodological issues of
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Department of Obstetrics and Gynecology, University of Oulu and Oulu University Hospital, Medical Research Center, PEDEGO Research Unit, Oulu, Finland
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due to CVD, osteoporosis and fractures. In addition, impairment of cognitive functions, dementia, Parkinsonism, and reduced sexual function and psychological well-being have been reported ( 12 ). Most of the evidence comes from observational studies of
Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Section for Endocrinology, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
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Section for Endocrinology, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
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Endocrine Out-Patient Clinic, Carlanderska Hospital, Gothenburg, Sweden
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doses, laboratory analyses, blood pressure, and the occurrence of other comorbidities and complications, such as renal failure and soft tissue calcifications, as well as fracture history were recorded. Patients were divided into two different groups
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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Department of Paediatric Endocrinology, Astrid Lindgren Children Hospital, Karolinska University Hospital, Stockholm, Sweden
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Department of Pediatric Endocrinology, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France
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disorders in addition to decreased bone health with increased fracture incidence for all groups ( 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ). A healthy lifestyle can modify and prevent many of these
Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
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Department of General Surgery, St. Elisabeth’s Hospital, Graz, Austria
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) Bone Limited available data in ICU survivors suggest impaired bone health and high fracture risk ( 38 , 39 , 40 , 41 , 83 ). 1,25(OH)(2)D(3) is known primarily as a regulator of calcium, but it also controls phosphate (re)absorption at the
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/3 radius or low-energy fracture, glomerular filtration rate (GFR) of <60 mL/min, nephrocalcinosis, renal stones or high stone risk). Table 1 presents the latest guidelines in comparison with older ones for the management of asymptomatic pHPT. Data from
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Introduction Osteoporosis is a systemic bone disease characterized by decrease in bone mass and damage to the microstructure of bone tissue, resulting in increased bone fragility and susceptibility to fracture ( 1 ). Pain due to osteoporosis