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Yiqiang Huang Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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Lin-ang Wang Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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Qiubo Xie Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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Jian Pang Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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Luofu Wang Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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Yuting Yi Geneplus-Beijing Institute, Beijing, People’s Republic of China

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Jun Zhang Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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Yao Zhang Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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Rongrong Chen Geneplus-Beijing Institute, Beijing, People’s Republic of China

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Weihua Lan Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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Dianzheng Zhang Department of Bio-Medical Sciences, Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA

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Jun Jiang Department of Urology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, People’s Republic of China

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&E-stained tumor specimens ( Fig. 1 ) and tumor-specific expression of CgA (chromogranin A), Syn (synaptophysin), CD56 (neural cell adhesion molecule 1), S-100 (S100 calcium-binding protein B), CK (choline kinase beta), MelanA (protein melan-A), HMB45 (human

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0325
Volume/Issue:
Volume 7: Issue 12
Open access
Emmi Naskali Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

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Katja Dettmer Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

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Peter J Oefner Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

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Pedro A B Pereira Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland

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Kai Krohn Clinical Research Institute HUCH Ltd, Biomedicum Helsinki 1, Helsinki, Finland

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Petri Auvinen Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland

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Annamari Ranki Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

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Nicolas Kluger Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

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chromogranin A and 5-HT ( 9 , 10 , 12 ). We previously observed that severe constipation symptoms were associated with the lack of 5-HT expression in the intestinal tract ( 9 ) and Scarpa and coworkers reported that 5-HT serum levels were significantly lower

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Research Article
DOI:
https://doi.org/10.1530/EC-18-0513
Volume/Issue:
Volume 8: Issue 1
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Xu Han Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Xuefeng Xu Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Hongyun Ma Department of Pancreatic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China

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Yuan Ji Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China

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Dansong Wang Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Tiantao Kuang Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Wenchuan Wu Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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Bin Song Department of Pancreatic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China

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Gang Li Department of Pancreatic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China

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Gang Jin Department of Pancreatic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China

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Wenhui Lou Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

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. ( https://doi.org/10.1038/modpathol.2010.166 ) 22 Kim T Tao-Cheng JH Eiden LE Loh YP . Chromogranin A, an ‘on/off’ switch controlling dense-core secretory granule biogenesis. Cell 2001 106 499 – 509 . ( https://doi.org/10.1016/S0092

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0388
Volume/Issue:
Volume 7: Issue 2
Open access
Sanjeet Kumar Jaiswal Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Vijaya Sarathi Department of Endocrinology, Vydehi Institute of Medical Sciences and Research Center, Bengaluru, Karnataka, India

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Saba Samad Memon Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Robin Garg Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Gaurav Malhotra Department of Nuclear Medicine, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India

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Priyanka Verma Department of Nuclear Medicine, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India

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Ravikumar Shah Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Manjeet Kaur Sehemby Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Virendra A Patil Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Swati Jadhav Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Anurag Ranjan Lila Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Nalini S Shah Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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Tushar R Bandgar Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India

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in DDD a well as PFNMN. The major limitations of our study are the small sample size and retrospective nature; thus MIB1-index, chromogranin A, and 68Ga-DOTATATE-PET/CT values were not available at several time points of follow up. Another major

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0292
Volume/Issue:
Volume 9: Issue 9
Open access
Filippo Ceccato Endocrinology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy

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Diego Cecchin Department of Neuroscience DNS, University of Padova, Padova, Italy
Nuclear Medicine Unit, Department of Medicine – DIMED, University-Hospital of Padova, Padova, Italy
Padova Neuroscience Center PNC, University of Padova, Padova, Italy

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Michele Gregianin Nuclear Medicine Unit, Castelfranco Veneto, Italy

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Giacomo Ricci Department of Neuroscience DNS, University of Padova, Padova, Italy

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Cristina Campi Padova Neuroscience Center PNC, University of Padova, Padova, Italy
Department of Mathematics ‘Tullio Levi-Civita’ DM, University of Padova, Padova, Italy

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Filippo Crimì Radiology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy

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Marta Bergamo Endocrinology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy

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Annibale Versari Nuclear Medicine Unit, Reggio Emilia, Italy

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Carmelo Lacognata Radiology Department, University-Hospital of Padova, Padova, Italy

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Federico Rea Thoracic Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University Hospital of Padova, Padova, Italy

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Mattia Barbot Endocrinology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy

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Carla Scaroni Endocrinology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy

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elevation of chromogranin A, 5/15 of NSE and 5/13 of CYFRA. Overweight or obesity was found in 9 patients, weight loss in 3, hypertension in 15, diabetes mellitus or impaired fasting glucose in 14, hypokalaemia in 15, osteoporosis or fracture in 13

Article Type:
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DOI:
https://doi.org/10.1530/EC-20-0089
Volume/Issue:
Volume 9: Issue 4
Open access
Catherine Cardot Bauters CHU Lille, Service d’Endocrinologie, Diabétologie, Métabolisme-Nutrition, Hôpital Claude Huriez, Lille, France

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Emmanuelle Leteurtre Univ. Lille, Inserm, CHU Lille, UMR-S 1277-CANTHER, Cancer Heterogeneity, Plasticity & Resistance to Therapies, Lille, France

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Bruno Carnaille CHU Lille, Service de Chirurgie Endocrine, Hôpital Claude Huriez, Lille, France

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Christine Do Cao CHU Lille, Service d’Endocrinologie, Diabétologie, Métabolisme-Nutrition, Hôpital Claude Huriez, Lille, France

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Stéphanie Espiard CHU Lille, Service d’Endocrinologie, Diabétologie, Métabolisme-Nutrition, Hôpital Claude Huriez, Lille, France

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Malo Penven CHU Lille, Service de Biochimie Hormonologie, Métabolisme, Nutrition-Oncologie, Centre de Biologie Pathologie Génétique, Lille, France

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Evelyne Destailleur CHU Lille, Service de Biochimie Hormonologie, Métabolisme, Nutrition-Oncologie, Centre de Biologie Pathologie Génétique, Lille, France

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Isabelle Szuster CHU Lille, Service de Biochimie Hormonologie, Métabolisme, Nutrition-Oncologie, Centre de Biologie Pathologie Génétique, Lille, France

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Tonio Lovecchio CHU Lille, Service de Biochimie Hormonologie, Métabolisme, Nutrition-Oncologie, Centre de Biologie Pathologie Génétique, Lille, France

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Julie Leclerc Univ. Lille, Inserm, CHU Lille, UMR-S 1277-CANTHER, Cancer Heterogeneity, Plasticity & Resistance to Therapies, Lille, France
CHU Lille, Service de Biochimie Hormonologie, Métabolisme, Nutrition-Oncologie, Centre de Biologie Pathologie Génétique, Lille, France

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Fredéric Frénois Univ. Lille, CHU Lille, EA-7364 RADEME, Faculté de Médecine, Lille, France

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Emmanuel Esquivel Dept Medicine, Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

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Patricia L M Dahia Dept Medicine, Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

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Emilie Ait-Yahya CHU Lille, Institut de Biochimie & Biologie Moléculaire, Centre de Biologie Pathologie Génétique, Lille, France

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Michel Crépin CHU Lille, Service de Biochimie Hormonologie, Métabolisme, Nutrition-Oncologie, Centre de Biologie Pathologie Génétique, Lille, France

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Pascal Pigny CHU Lille, Service de Biochimie Hormonologie, Métabolisme, Nutrition-Oncologie, Centre de Biologie Pathologie Génétique, Lille, France

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or adrenomedullary nodule. Plasma free normetanephrines were at the upper limit of the normal values. Pre-operatively, patient I-1 had high urinary normetanephrines (5x the upper limit range) and chromogranin-A levels (x3 the upper limit range). By

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Research Article
DOI:
https://doi.org/10.1530/EC-20-0460
Volume/Issue:
Volume 9: Issue 10
Open access
Tiina Vesterinen HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland

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Teijo Kuopio Department of Biological and Environmental Science, University of Jyväskylä and Department of Pathology, Central Finland Health Care District, Jyväskylä, Finland

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Maarit Ahtiainen Department of Education and Research, Central Finland Central Hospital, Jyväskylä, Finland

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Aija Knuuttila Department of Pulmonary Medicine, Heart and Lung Center, and Cancer Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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Harri Mustonen Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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Kaisa Salmenkivi HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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Johanna Arola HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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Caj Haglund Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland

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confirmed by routine immunohistochemical labeling for chromogranin A, synaptophysin and pan-cytokeratin. One hundred and thirty-one patients (78%) were diagnosed with TC and 37 (22%) with AC tumors. Surgery was the first-line treatment for all patients

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DOI:
https://doi.org/10.1530/EC-19-0308
Volume/Issue:
Volume 8: Issue 8
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Logan Mills Institute of Liver Studies, King’s College Hospital, London, UK

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Panagiotis Drymousis Department of Surgery and Cancer, Imperial College, London, UK

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Yogesh Vashist Department of General, Visceral and Thoracic Surgery, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany

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Christoph Burdelski Department of General, Visceral and Thoracic Surgery, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany

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Andreas Prachalias Department of Surgery, King’s College Hospital, London, UK

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Parthi Srinivasan Department of Surgery, King’s College Hospital, London, UK

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Krishna Menon Department of Surgery, King’s College Hospital, London, UK

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Corina Cotoi Department of Histopathology, King’s College Hospital, London, UK

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Saboor Khan Department of Surgery, University Hospitals Coventry and Warwickshire, Coventry, UK

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Judith Cave Department of Oncology, University Hospital, Southampton, UK

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Thomas Armstrong Department of Surgery, University Hospital, Southampton, UK

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Martin O Weickert Department of Endocrinology, University Hospitals Coventry and Warwickshire, Coventry, UK

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Jakob Izbicki Department of General, Visceral and Thoracic Surgery, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany

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Joerg Schrader Departments of Gastroenterology and Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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Andreja Frilling Department of Surgery and Cancer, Imperial College, London, UK

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John K Ramage Institute of Liver Studies, King’s College Hospital, London, UK

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Raj Srirajaskanthan Institute of Liver Studies, King’s College Hospital, London, UK

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defined as local invasion, vascular invasion, lymph node metastasis or distant metastasis (synchronous or metachronous); d CgA = chromogranin A. * P  < 0.05. ** P  < 0.005. Tumours >2 cm were significantly more likely to have local invasion

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DOI:
https://doi.org/10.1530/EC-17-0293
Volume/Issue:
Volume 6: Issue 8
Open access
Jean-Benoît Corcuff Department of Nuclear Medicine, Haut Lévêque Hospital, Pessac, France
Nutrition et Neurobiologie intégrée, UMR 1286, University of Bordeaux, Bordeaux, France
Groupe de Biologie Spécialisée, Société Française de Médecine Nucléaire, Paris, France

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Laurence Chardon Department of Biochemistry, Edouard Herriot Hospital, Lyon, France

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Ines El Hajji Ridah Biomnis, Lyon, France

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Julie Brossaud Department of Nuclear Medicine, Haut Lévêque Hospital, Pessac, France
Nutrition et Neurobiologie intégrée, UMR 1286, University of Bordeaux, Bordeaux, France
Groupe de Biologie Spécialisée, Société Française de Médecine Nucléaire, Paris, France

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:10.1177/000456329603300106 ) 37 Joy T Walsh G Tokmakejian S Van Uum SH. Increase of urinary 5-hydroxyindoleacetic acid excretion but not serum chromogranin. A following over-the-counter 5-hydroxytryptophan intake . Canadian Journal

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DOI:
https://doi.org/10.1530/EC-17-0071
Volume/Issue:
Volume 6: Issue 6
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E T Aristizabal Prada Department of Internal Medicine IV, Campus Grosshadern, University-Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany

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C J Auernhammer Department of Internal Medicine IV, Campus Grosshadern, University-Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany

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and decreases secretion of neuroendocrine markers as neuron-specific enolase, synaptophysin, chromogranin A, represses tryptophan hydroxylase 1 expression and decreases serotonin and 5-hydroxytryptamine secretion ( 166 , 169 ). Ascl1 has been

Article Type:
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DOI:
https://doi.org/10.1530/EC-17-0286
Volume/Issue:
Volume 7: Issue 1
Open access