Lizhi Zhang
Lizhi Zhang
Department of Endocrinology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
Department of Endocrinology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Department of Endocrinology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Jinwei He
Jinwei He
Department of Osteoporosis and Bone Disease, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China
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Xiang Sun
Xiang Sun
Shanghai Institute of Technology, Shanghai, China
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Dongyue Pang
Dongyue Pang
Department of Endocrinology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
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Jingjing Hu
Jingjing Hu
Department of Endocrinology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China
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Bo Feng
Bo Feng
Department of Endocrinology, Jiading Branch of Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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on the cell surface. GIPR SNP rs10423928 has been studied frequently. It consists of the major allele T and the minor allele A. Individuals with the T/T genotype who consume a high-carbohydrate/low-fat diet have a lower risk of type 2 diabetes ( 16
Helle Keinicke
Helle Keinicke
Insulin and Device Trial Operations, Novo Nordisk A/S, Søborg, Denmark
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Gao Sun
Gao Sun
Pharmacology and Histopathology, Novo Nordisk A/S, China
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Caroline M Junker Mentzel
Caroline M Junker Mentzel
Department of Experimental Animal Models, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark
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Merete Fredholm
Merete Fredholm
Department of Veterinary Clinical and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark
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Linu Mary John
Linu Mary John
Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark
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Birgitte Andersen
Birgitte Andersen
Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark
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Kirsten Raun
Kirsten Raun
Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark
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Marina Kjaergaard
Marina Kjaergaard
Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark
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manufacturer’s instructions, the reactions were incubated 5 min at 25°C, 30 min at 42°C and 5 min at 85°C. The cDNA was stored at −80°C until use. Primer design Selection of the genes of interest in the liver was focused on lipid and carbohydrate
Teresa Lam
Teresa Lam
School of Medicine, Western Sydney University, Penrith, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, Westmead, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
Department of Diabetes and Endocrinology, Westmead Hospital, Westmead, New South Wales, Australia
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Mark McLean
Mark McLean
School of Medicine, Western Sydney University, Penrith, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
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Amy Hayden
Amy Hayden
Department of Radiation Oncology, Blacktown Hospital, Blacktown, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, Westmead, New South Wales, Australia
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Crown Princess Mary Cancer Centre, Westmead Hospital, Westmead, New South Wales, Australia
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Anne Poljak
Anne Poljak
Bioanalytical Mass Spectrometry Facility and School of Medical Sciences, UNSW Sydney, Sydney, New South Wales, Australia
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Birinder Cheema
Birinder Cheema
School of Science and Health, Western Sydney University, Penrith, New South Wales, Australia
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Howard Gurney
Howard Gurney
Crown Princess Mary Cancer Centre, Westmead Hospital, Westmead, New South Wales, Australia
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Glenn Stone
Glenn Stone
School of Computing, Engineering and Mathematics, Western Sydney University, Penrith, New South Wales, Australia
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Neha Bahl
Neha Bahl
School of Medicine, Western Sydney University, Penrith, New South Wales, Australia
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Navneeta Reddy
Navneeta Reddy
Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
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Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
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Haleh Shahidipour
Haleh Shahidipour
School of Medicine, Western Sydney University, Penrith, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
School of Medicine, UNSW Sydney, Sydney, New South Wales, Australia
Translational Health Research Institute, Penrith, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
School of Medicine, UNSW Sydney, Sydney, New South Wales, Australia
Translational Health Research Institute, Penrith, New South Wales, Australia
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Vita Birzniece
Vita Birzniece
School of Medicine, Western Sydney University, Penrith, New South Wales, Australia
Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
School of Medicine, UNSW Sydney, Sydney, New South Wales, Australia
Translational Health Research Institute, Penrith, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, Blacktown, New South Wales, Australia
Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
School of Medicine, UNSW Sydney, Sydney, New South Wales, Australia
Translational Health Research Institute, Penrith, New South Wales, Australia
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are presented as mean ± s.e.m. ; P value is for UC vs PRT group. ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; Cox, carbohydrate oxidation; Fox, fat oxidation; GGT, gamma-glutamyl transferase; HDL, high
Huguette S Brink
Huguette S Brink
Department of Endocrinology, Maasstad Hospital, Rotterdam, The Netherlands
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Aart Jan van der Lely
Aart Jan van der Lely
Department of Endocrinology, Erasmus University MC, Rotterdam, The Netherlands
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Joke van der Linden
Joke van der Linden
Department of Endocrinology, Maasstad Hospital, Rotterdam, The Netherlands
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SH Spijkerman AM Baan C Forouhi NG Herder C Rathmann W. Diabetes in Europe: an update . Diabetes Research and Clinical Practice 2014 103 206 – 217 . ( doi:10.1016/j.diabres.2013.11.007 ) 3 Catalano PM. Carbohydrate
C L Bodinham
C L Bodinham
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L Smith
L Smith
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E L Thomas
E L Thomas
Nutrition, Metabolic and Molecular Imaging Group, Department of Food and Nutritional Sciences, Metabolism and Diabetes Research Group, Faculty of Health and Medical Sciences, University of Surrey, Leggett Building, Guildford, Surrey GU2 7WG, UK
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J D Bell
J D Bell
Nutrition, Metabolic and Molecular Imaging Group, Department of Food and Nutritional Sciences, Metabolism and Diabetes Research Group, Faculty of Health and Medical Sciences, University of Surrey, Leggett Building, Guildford, Surrey GU2 7WG, UK
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J R Swann
J R Swann
Nutrition, Metabolic and Molecular Imaging Group, Department of Food and Nutritional Sciences, Metabolism and Diabetes Research Group, Faculty of Health and Medical Sciences, University of Surrey, Leggett Building, Guildford, Surrey GU2 7WG, UK
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A Costabile
A Costabile
Nutrition, Metabolic and Molecular Imaging Group, Department of Food and Nutritional Sciences, Metabolism and Diabetes Research Group, Faculty of Health and Medical Sciences, University of Surrey, Leggett Building, Guildford, Surrey GU2 7WG, UK
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D Russell-Jones
D Russell-Jones
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A M Umpleby
A M Umpleby
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M D Robertson
M D Robertson
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Randomised Controlled Trial Number 10727538. Study design The study was carried out as a single-blind, randomized dietary intervention crossover study, comparing RS derived from maize with a placebo that was matched for available carbohydrate content
Lesley A Hill
Lesley A Hill
Departments of Cellular and Physiological Sciences and Obstetrics and Gynaecology, The University of British Columbia, Vancouver, British Columbia, Canada
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Zeynep Sumer-Bayraktar
Zeynep Sumer-Bayraktar
School of Life and Environmental Science, Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia
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John G Lewis
John G Lewis
Canterbury Health Laboratories, Christchurch, New Zealand
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Eva Morava
Eva Morava
Mayo Clinic, Department of Clinical Genomics, CIM, Rochester, Minnesota, USA
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Morten Thaysen-Andersen
Morten Thaysen-Andersen
Department of Molecular Sciences, Macquarie University, Sydney, New South Wales, Australia
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Geoffrey L Hammond
Geoffrey L Hammond
Departments of Cellular and Physiological Sciences and Obstetrics and Gynaecology, The University of British Columbia, Vancouver, British Columbia, Canada
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occupied by an ensemble of complex carbohydrates ( 11 ) that contribute to its electrophoretic heterogeneity ( 12 ). Importantly, N -glycosylation at N347 within the RCL of human CBG modulates how efficiently proteases cleave the RCL ( 13 ), and evidence
Benjamin D Maylor
Benjamin D Maylor
Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK
Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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Julia K Zakrzewski-Fruer
Julia K Zakrzewski-Fruer
Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK
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Charlie J Orton
Charlie J Orton
Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK
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Daniel P Bailey
Daniel P Bailey
Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK
Centre for Physical Activity in Health and Disease, Brunel University London, Uxbridge, UK
Division of Sport, Health and Exercise Sciences, Department of Life Sciences, Brunel University London, Uxbridge, UK
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Centre for Physical Activity in Health and Disease, Brunel University London, Uxbridge, UK
Division of Sport, Health and Exercise Sciences, Department of Life Sciences, Brunel University London, Uxbridge, UK
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breakfast meal comprising ecologically valid food items ( 25 , 26 ). The macronutrient composition was 55% carbohydrate, 30% fat, and 15% protein; the meal glycaemic index was 79. Energy requirements for each participant were estimated using the Mifflin
Jukka Koffert
Jukka Koffert
Department of Gastroenterology, Turunmaa Hospital, Turku, Finland
Turku PET Centre, University of Turku, Turku, Finland
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Turku PET Centre, University of Turku, Turku, Finland
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Henri Honka
Henri Honka
Turku PET Centre, University of Turku, Turku, Finland
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Jarmo Teuho
Jarmo Teuho
Department of Gastroenterology, Turunmaa Hospital, Turku, Finland
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Saila Kauhanen
Saila Kauhanen
Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland
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Saija Hurme
Saija Hurme
Institute of Biostatistics, University of Turku, Turku, Finland
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Riitta Parkkola
Riitta Parkkola
Turku PET Centre, University of Turku, Turku, Finland
Department of Radiology, University of Turku and Turku University Hospital, Turku, Finland
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Department of Radiology, University of Turku and Turku University Hospital, Turku, Finland
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Vesa Oikonen
Vesa Oikonen
Turku PET Centre, University of Turku, Turku, Finland
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Andrea Mari
Andrea Mari
Institute of Neuroscience, National Research Council, Padua, Italy
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Andreas Lindqvist
Andreas Lindqvist
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Nils Wierup
Nils Wierup
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Leif Groop
Leif Groop
Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden
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Pirjo Nuutila
Pirjo Nuutila
Turku PET Centre, University of Turku, Turku, Finland
Department of Endocrinology, Turku University Hospital, Turku, Finland
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Department of Endocrinology, Turku University Hospital, Turku, Finland
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Nutrition, Amsterdam, Netherlands) contained 250 kcal energy, and consisted of 40, 6 and 9 g of carbohydrates, fat and protein, respectively. During the 90-min time period 15 O-water and 15 O-carbon monoxide PET-scans were repeated twice ( Supplementary
Wolfgang Koechling
Wolfgang Koechling
Ferring Pharmaceuticals A/S, Copenhagen, Denmark
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Daniel Plaksin
Daniel Plaksin
Bio-Technology General Israel Ltd, Ferring Pharmaceuticals, Kiryat Malachi, Israel
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Glenn E Croston
Glenn E Croston
Croston Consulting, San Diego, California, USA
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Janni V Jeppesen
Janni V Jeppesen
The Laboratory of Reproductive Biology, The Department of Fertility at The Juliane Marie Centre, Rigshospitalet, Copenhagen University Hospital and The University of Copenhagen, Copenhagen, Denmark
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Kirsten T Macklon
Kirsten T Macklon
The Laboratory of Reproductive Biology, The Department of Fertility at The Juliane Marie Centre, Rigshospitalet, Copenhagen University Hospital and The University of Copenhagen, Copenhagen, Denmark
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Claus Yding Andersen
Claus Yding Andersen
The Laboratory of Reproductive Biology, The Department of Fertility at The Juliane Marie Centre, Rigshospitalet, Copenhagen University Hospital and The University of Copenhagen, Copenhagen, Denmark
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A Damm JB Kamerling JP de Boer W Wijnands RA Vliegenthart JF. Isolation and structure determination of the intact sialylated N-linked carbohydrate chains of recombinant human follitropin expressed in Chinese hamster ovary cells
R Solomon-Zemler
R Solomon-Zemler
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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L Basel-Vanagaite
L Basel-Vanagaite
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
Felsenstein Medical Research Center, Petach Tikva, Israel
Pediatric Genetics, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
Felsenstein Medical Research Center, Petach Tikva, Israel
Pediatric Genetics, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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D Steier
D Steier
Day Hospitalization Department, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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S Yakar
S Yakar
David B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, New York, USA
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E Mel
E Mel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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M Phillip
M Phillip
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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L Bazak
L Bazak
Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
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D Bercovich
D Bercovich
Tel-Hai College, Tel-Hai, Israel
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H Werner
H Werner
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Shalom and VardaYoran Institute for Human Genome Research, Tel Aviv University, Tel Aviv, Israel
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Shalom and VardaYoran Institute for Human Genome Research, Tel Aviv University, Tel Aviv, Israel
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L de Vries
L de Vries
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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hypoglycemic events occurred day and night and persisted despite frequent feedings with carbohydrate-enriched meals and Proglycem (diazoxide) treatment. A percutaneous feeding gastrostomy was also inserted as the gastro-esophageal reflux was associated with
