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hypergonadotropic hypogonadism, small testes, and infertility ( 17 ). Moreover, other manifestations include neurocognitive, psychosocial, cardiovascular, metabolic, malignancies, venous thromboembolism, and bone-related conditions ( 1 , 17 ). This review deals
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Johannesdottir SA Horvath-Puho E Dekkers OM Cannegieter SC Jorgensen JO Ehrenstein V Vandenbroucke JP Pedersen L & Sorensen HT . Use of glucocorticoids and risk of venous thromboembolism: a nationwide population-based case-control study
K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway
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K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden
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Department of Sleep, Landspitali University Hospital Reykjavík, Reykjavik, Iceland
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Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia
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Albacete Faculty of Medicine, Castilla-La Mancha University, Albacete, Spain
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The National Research Center for the Working Environment, Copenhagen, Denmark
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K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Bergen, Norway
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cancer and venous thromboembolism in HRT users, resulting in a marked decrease in prescription the following years ( 46 , 47 ). We found no evidence that age at menarche is a predictor of the timing of menopause. It seems intriguing that these two
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was 15.9 months (range, 8–36), with a median follow-up of 28 months (range, 13–36) ( 23 ). No information on bone health was provided. Cardiac failure was observed in 7.1% of the population and venous thromboembolism (VTE) in 27.7%, which is not
Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK
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Centre for Endocrinology, William Harvey Research Institute, Barts and The London Medical School, Queen Mary University of London, London, UK
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Department of Paediatric Endocrinology, Makarios Children's Hospital, Nicosia, Cyprus
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Sussex Community NHS Trust, Brighton, UK
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Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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The University of Dublin, Trinity College Dublin, Dublin, Republic of Ireland
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options such as oestradiol valerate, or less preferably synthetic oestrogens such as ethinyloestradiol, are best avoided because of the increased risk of hypertension and venous thromboembolism. Available preparations can be found in the British National