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. Allolio et al. demonstrated correlations between serum progesterone and salivary cortisol during pregnancy. They suggest that elevated plasma free cortisol levels may result from the anti-glucocorticoid effects of elevated progesterone concentrations in
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Ruth and Bruce Rappaport School of Medicine, The Technion Institute of Technology, Haifa, Israel
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purified human menopausal gonadotropin alone (Menopur, Ferring, Israel); or (iii) a combination of both. Estrogen and progesterone concentrations were routinely measured at every follow-up visit, including the day of β-hCG (Ovitrelle Merck
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female reproductive events. Further, ovarian tumors are considered sensitive to sex steroid hormones, as they are mediated by specific androgen, estrogen, and progesterone receptors ( 3 ). Additionally, the steroid hormone receptor shows a particular
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele, Rome, Italy
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Medical Department Pronokal Group, Barcelona, Spain
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OH-progesterone, and progesterone) by liquid chromatography-tandem mass spectrometry (LC-MS/MS), at the Center for Applied Biomedical Research of the University of Bologna, S. Orsola Hospital. The same day, a medical examination was made, during
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elements, enhancement of T suppressor cell activity, promotion of TH1 response and activation of CD8C ( 49 ). In addition, progesterone levels may inhibit macrophage proliferation, IL6 synthesis and peripheral antibody production ( 50 ). Also, in vivo and
Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi’an, Shaanxi, People’s Republic of China
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performed. The premature ovarian atrophy was diagnosed by invisibility of both ovaries ( Fig. 4G and H ) accompanied by the atrophy of uterus. Serum sexual hormones were then detected by radioimmunoassay. Estradiol and progesterone levels were low ( Table
Department of Endocrinology, Diabetes and Nutrition, University Hospital of Bordeaux, Bordeaux, France
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Sorbonne Université, F-75013, Paris, France
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). Moreover, estradiol and progesterone receptor levels were also higher in FAs recently detected ( 8 ). The possible role of prolactin has also been suspected ( 9 ). However, no established systemic hormonal imbalance has been demonstrated as of yet ( 9 , 10
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measured, whereas Free Androgen Index (FAI) was calculated on follicular phase. Progesterone levels were measured on luteal phase of menstrual cycle. LH, FSH and testosterone were determined based on Chemiluminescence (Elecsys 2010, Roche Diagnostics
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’ pathway that bypasses the conventional intermediates androstenedione and testosterone ( 8 , 9 , 10 ). In this pathway, progesterone and 17OH-progesterone are subsequently converted to dihydroprogesterone (DHP), allopregnanolone, 17-OH allopregnanolone
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lower levels of progesterone. Data derived from the studies in which sleep was evaluated in relation to pregnancy, phase of menstrual cycle, menopause or hormone replacement therapy, suggests that progesterone has a protective effect against OSA ( 34